Zobrazeno 1 - 10
of 4 694
pro vyhledávání: '"A E, Shaw"'
Autor:
Stephen R. Spellman, Rodney Sparapani, Martin Maiers, Bronwen E. Shaw, Purushottam Laud, Caitrin Bupp, Meilun He, Steven M. Devine, Brent R. Logan
Publikováno v:
Blood Advances, Vol 8, Iss 23, Pp 6082-6087 (2024)
Abstract: We investigated the impact of donor characteristics on outcomes in allogeneic hematopoietic cell transplantation (HCT) recipients using a novel machine learning approach, the Nonparametric Failure Time Bayesian Additive Regression Trees (NF
Externí odkaz:
https://doaj.org/article/07e273514c88493a938c0aede2fe6584
Autor:
Md Hamidul Huque, Scherazad Kootar, Kim M. Kiely, Craig S. Anderson, Martin van Boxtel, Henry Brodaty, Perminder S. Sachdev, Michelle Carlson, Annette L. Fitzpatrick, Rachel A. Whitmer, Miia Kivipelto, Louisa Jorm, Sebastian Köhler, Nicola T. Lautenschlager, Oscar L. Lopez, Jonathan E. Shaw, Fiona E. Matthews, Ruth Peters, Kaarin J. Anstey
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background We aimed to develop risk tools for dementia, stroke, myocardial infarction (MI), and diabetes, for adults aged ≥ 65 years using shared risk factors. Methods Data were obtained from 10 population-based cohorts (N = 41,755) with m
Externí odkaz:
https://doaj.org/article/dd6e1671c0034757a51e4b8545b5d355
Mutations in the tail and rod domains of the neurofilament heavy‐chain gene increase the risk of ALS
Autor:
Heather Marriott, Thomas P. Spargo, Ahmad Al Khleifat, Peter M Andersen, Nazli A. Başak, Johnathan Cooper‐Knock, Philippe Corcia, Philippe Couratier, Mamede deCarvalho, Vivian Drory, Marc Gotkine, John E. Landers, Russell McLaughlin, Jesús S. Mora Pardina, Karen E. Morrison, Susana Pinto, Christopher E. Shaw, Pamela J. Shaw, Vincenzo Silani, Nicola Ticozzi, Philip vanDamme, Leonard H. van denBerg, Patrick Vourc'h, Markus Weber, Jan H. Veldink, Project MinE ALS Sequencing Consortium, Richard J. Dobson, Patrick Schwab, Ammar Al‐Chalabi, Alfredo Iacoangeli
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 7, Pp 1775-1786 (2024)
Abstract Objective Neurofilament heavy‐chain gene (NEFH) variants are associated with multiple neurodegenerative diseases, however, their relationship with ALS has not been robustly explored. Still, NEFH is commonly included in genetic screening pa
Externí odkaz:
https://doaj.org/article/3bcb8a1d9b3c4724a5b304747dd4abc5
Autor:
Hassane Alami, Pascale Lehoux, Chrysanthi Papoutsi, Sara E. Shaw, Richard Fleet, Jean-Paul Fortin
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-24 (2024)
Abstract Background Artificial intelligence (AI) technologies are expected to “revolutionise” healthcare. However, despite their promises, their integration within healthcare organisations and systems remains limited. The objective of this study
Externí odkaz:
https://doaj.org/article/3f7e2271f0464ed3901692d003865aec
Autor:
Pascal Buri, Simone Fatichi, Thomas E. Shaw, Catriona L. Fyffe, Evan S. Miles, Michael J. McCarthy, Marin Kneib, Shaoting Ren, Achille Jouberton, Stefan Fugger, Li Jia, Jing Zhang, Cong Shen, Chaolei Zheng, Massimo Menenti, Francesca Pellicciotti
Publikováno v:
Geo-spatial Information Science, Vol 27, Iss 3, Pp 703-727 (2024)
Mountains are important suppliers of freshwater to downstream areas, affecting large populations in particular in High Mountain Asia (HMA). Yet, the propagation of water from HMA headwaters to downstream areas is not fully understood, as interactions
Externí odkaz:
https://doaj.org/article/e02cb7759bd8486386e68717b525a79a
Autor:
Ingrid M. Saldana-Guerrero, Luis F. Montano-Gutierrez, Katy Boswell, Christoph Hafemeister, Evon Poon, Lisa E. Shaw, Dylan Stavish, Rebecca A. Lea, Sara Wernig-Zorc, Eva Bozsaky, Irfete S. Fetahu, Peter Zoescher, Ulrike Pötschger, Marie Bernkopf, Andrea Wenninger-Weinzierl, Caterina Sturtzel, Celine Souilhol, Sophia Tarelli, Mohamed R. Shoeb, Polyxeni Bozatzi, Magdalena Rados, Maria Guarini, Michelle C. Buri, Wolfgang Weninger, Eva M. Putz, Miller Huang, Ruth Ladenstein, Peter W. Andrews, Ivana Barbaric, George D. Cresswell, Helen E. Bryant, Martin Distel, Louis Chesler, Sabine Taschner-Mandl, Matthias Farlik, Anestis Tsakiridis, Florian Halbritter
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Early childhood tumours arise from transformed embryonic cells, which often carry large copy number alterations (CNA). However, it remains unclear how CNAs contribute to embryonic tumourigenesis due to a lack of suitable models. Here we empl
Externí odkaz:
https://doaj.org/article/869f81138e26465185ec2a1246dd0cf6
Autor:
Cynthia Iglesias, Gary Abel, Claire Reidy, Jackie van Dael, Luis Beltran Galindo, Helene Raynsford, Sara E Shaw, John Campbell, Vijay Gc, Trisha Greenhalgh, Stuart D Faulkner, Michele Siciliano, Chrysanthi Papoutsi
Publikováno v:
NIHR Open Research, Vol 4 (2024)
Background General practice is facing an unprecedented challenge in managing the consequences of the pandemic. In the midst of a policy drive to balance remote and in-person service provision, substantial workload pressures remain, together with incr
Externí odkaz:
https://doaj.org/article/7322da9311c0490397121f4a2786a5fa
Autor:
Kirsten E. Shaw, Kevin M. Harris, Amy Diedrich, Amy K. Holbrook, Larissa Stanberry, Michelle D. Carlson, Retu Saxena
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 16 (2024)
Externí odkaz:
https://doaj.org/article/67d1fd441c5e42bea77aa8ad6fab3b05
Autor:
Anjana Rajendra, Nicola P. Bondonno, Liezhou Zhong, Simone Radavelli-Bagatini, Kevin Murray, Stephanie R. Rainey-Smith, Samantha L. Gardener, Lauren C. Blekkenhorst, Dianna J. Magliano, Jonathan E. Shaw, Robin M. Daly, Kaarin J. Anstey, Joshua R. Lewis, Jonathan M. Hodgson, Catherine P. Bondonno
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionDietary nitrate is potentially beneficial for cardiovascular, cerebrovascular, and nervous systems due to its role as a nitric oxide (NO) precursor. Increased nitrate intake improves cardiovascular health and therefore could protect again
Externí odkaz:
https://doaj.org/article/701a5ff71a674806bd13f51ff1358f91
Autor:
Michelle Guppy, Paul Glasziou, Mark Jones, Elaine Beller, Jonathan E Shaw, Elizabeth Barr, Jenny Doust
Publikováno v:
BJGP Open, Vol 8, Iss 2 (2024)
Background: The stages of chronic kidney disease (CKD) and estimated glomerular filtration rate (eGFR) reference ranges are currently determined without considering age. Aim: To determine whether a chart that graphs age with eGFR helps GPs make bette
Externí odkaz:
https://doaj.org/article/6781ed7c1f2142b19c26cafa4c81b698