Zobrazeno 1 - 10
of 55
pro vyhledávání: '"A E, New"'
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The brain is responsible for maintaining whole-body energy homeostasis by changing energy input and availability. The hypothalamus and dorsal vagal complex (DVC) are the primary sites of metabolic control, able to sense both hormones and nutrients an
Externí odkaz:
https://doaj.org/article/5ca24a1da1be47f7a99e3fa5be5c7ca5
Autor:
Arianna Fozzato, Lauryn E. New, Joanne C. Griffiths, Bianca Patel, Susan A. Deuchars, Beatrice M. Filippi
ObjectivesBrown adipose tissue (BAT) is a potent thermogenic organ, activated by the central nervous system (CNS) through direct noradrenergic sympathetic innervation. Dysregulation of signalling modules in selective CNS areas such as the nucleus of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee3584d82aa34745edc5d3b3efd1fc7
https://doi.org/10.1101/2023.01.04.522581
https://doi.org/10.1101/2023.01.04.522581
Autor:
Kristy Kikly, Howard Barff Broughton, William Chang, Selma Sapmaz, Richard Morphy, Holly A. Bina, Jim D. Durbin, Sherry Y Guo, Timothy Ivo Richardson, Jimmy P Steele, Ryan Edward Stites, Brian G. Getman, Vaught Grant Matthews, Veavi Ching-Yun Chang, Pamela K. Shetler, Greg L Durst, Denise D Edmondson, Rob Barr, Helene Rudyk, Charles Willis Lugar, Nita J. Patel, Christian Alexander Clarke, Kelly Wayne Furness, Nicole E New, David K. Clawson, Keith R. Stayrook, Mark Chambers, Brian Michael Mathes, Stephanie L. Stout, Wendy H. Gough
Publikováno v:
Journal of Medicinal Chemistry. 64:5470-5484
The Th17 pathway has been implicated in autoimmune diseases. The retinoic acid receptor-related orphan receptor C2 (RORγt) is a master regulator of Th17 cells and controls the expression of IL-17A. RORγt is expressed primarily in IL-17A-producing l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a80dc241f7e50c8ddb367cc37ea913c
https://doi.org/10.1021/acs.jmedchem.0c01918
https://doi.org/10.1021/acs.jmedchem.0c01918
Autor:
E.H. Lim, A. Lim, J.S. Khara, J. Cheong, J. Fong, S. Sivanesan, M. Griffiths, E. New, S.C. Lee
Publikováno v:
ESMO Open. 8:101324
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a88ac31d077ac09045d53f9f618cc6c
https://doi.org/10.1016/j.esmoop.2023.101324
https://doi.org/10.1016/j.esmoop.2023.101324
Manipulation of neural stem cell proliferation and differentiation in the postnatal CNS is receiving significant attention due to therapeutic potential. In the spinal cord, such manipulations may promote repair in conditions such as multiple sclerosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd620b20e8fa3cf69849465eafcdf5a
https://doi.org/10.1101/2022.04.21.489053
https://doi.org/10.1101/2022.04.21.489053
Autor:
Charles W, Lugar, Christian A, Clarke, Richard, Morphy, Helene, Rudyk, Selma, Sapmaz, Ryan E, Stites, Grant M, Vaught, Kelly, Furness, Howard B, Broughton, Greg L, Durst, David K, Clawson, Stephanie L, Stout, Sherry Y, Guo, Jim D, Durbin, Keith R, Stayrook, Denise D, Edmondson, Kristy, Kikly, Nicole E, New, Holly A, Bina, Mark G, Chambers, Pamela, Shetler, William Y, Chang, Veavi Ching-Yun, Chang, Rob, Barr, Wendy H, Gough, Jimmy P, Steele, Brian, Getman, Nita, Patel, Brian M, Mathes, Timothy I, Richardson
Publikováno v:
Journal of medicinal chemistry. 64(9)
The Th17 pathway has been implicated in autoimmune diseases. The retinoic acid receptor-related orphan receptor C2 (RORγt) is a master regulator of Th17 cells and controls the expression of IL-17A. RORγt is expressed primarily in IL-17A-producing l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef03d39fb502b855beadc34c7a19e1e7
https://pubmed.ncbi.nlm.nih.gov/33852312
https://pubmed.ncbi.nlm.nih.gov/33852312
Publikováno v:
Molecular Metabolism
Objectives The dorsal vagal complex (DVC) senses insulin and controls glucose homeostasis, feeding behaviour and body weight. Three-days of high-fat diet (HFD) in rats are sufficient to induce insulin resistance in the DVC and impair its ability to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e4f51cf83adc0dfa4623b965fe0717
https://doi.org/10.1016/j.molmet.2020.101123
https://doi.org/10.1016/j.molmet.2020.101123
Autor:
Alyn H. Morice, Steven J. Compton, Jennifer E. Mitchell, S A Mulrennan, Jack A Kastelik, Laura R. Sadofsky, Norman E. New, Anne Campbell
Publikováno v:
Experimental Lung Research. 31:295-306
TRPV1 is a modulator of noxious stimuli known to be important in the cough reflex. We have compared the expression of TRPV1 in normal human airways and those from patients with chronic cough and found that there is up regulation in airways smooth mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772d33f7a2b47769403e037d74984f18
https://doi.org/10.1080/01902140590918803
https://doi.org/10.1080/01902140590918803
Autor:
George E. New
Publikováno v:
Journal of Managerial Psychology. 11:44-51
Provides a framework for the assessment of a person’s competencies. Describes three types of competence: job specific (JSC), general management (GMC) and corporate specific (CSC). JSCs and GMCs relate to performance in a particular job, while CSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db2bc2bec36392864d1f3c9207a2c5d9
https://doi.org/10.1108/02683949610150051
https://doi.org/10.1108/02683949610150051
Publikováno v:
Bulletin of Health Research, Vol 6, Iss 1 Mar (2012)
Penyakit rabies telah dikenal di Indonesia sejak tahun 1889, dan mengingat tidak adanya data yang diteliti mengenai penderita rabies, maka perlu dilakukan suatu penelitian. Penelitian dilakukan oleh NAMRU-2 bersama Departemen Kesehatan dari tahun 197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::cae22ea285d8281c865b5f68f2eb8793
http://ejournal.litbang.kemkes.go.id/index.php/BPK/article/view/341
http://ejournal.litbang.kemkes.go.id/index.php/BPK/article/view/341