Zobrazeno 1 - 10
of 11
pro vyhledávání: '"A E, Meekhof"'
Publikováno v:
Experimental Physiology. 98:1164-1177
It has been recently shown that various stress-inducing manipulations in isolated ventricular myocytes may lead to significant remodeling of t-tubules. Osmotic stress is one of the most common complications in various experimental and clinical settin
Publikováno v:
Human Molecular Genetics. 20:3346-3355
The abnormal glycosylation and loss of extracellular matrix receptor function of the protein dystroglycan (DG) lead to the development of muscular dystrophy and cardiomyopathy. Dystroglycan is an important receptor for extracellular matrix proteins,
Autor:
Alison E. Meekhof, Stefan M.V. Freund
Publikováno v:
Journal of Molecular Biology. 286:579-592
The energy landscape for the denatured state of a protein provides a key to understanding early folding events. We have attempted to map this landscape for the third fibronectin type III domain from human tenascin (TNfn3), a compact 9.5 kDa beta-sand
Autor:
Stefan M.V. Freund, Alison E. Meekhof
Publikováno v:
Journal of Biomolecular NMR. 14:13-22
In proteins, dynamic mobility is an important feature of structure, stability, and biomolecular recognition. Uniquely sensitive to motion throughout the milli- to picosecond range, rates of transverse relaxation, R2, are commonly obtained for the cha
Publikováno v:
Journal of Molecular Biology. 282:181-194
The third fibronectin type III domain from human tenascin adopts a compact beta-sandwich fold. Its boundaries were originally selected to encode a 90-residue domain (TNfn31-90). We conclude that the dynamic properties of TNfn3 are more accurately rep
Publikováno v:
Journal of Physical Organic Chemistry. 10:499-513
Thermodynamic stability properties of 11 p-substituted trityl and seven 9-phenylxanthyl carbocations are reported in sulfolane and of their conjugate carbanions in DMSO. The cations are compared by calorimetric heats of hydride transfer from cyanobor
Publikováno v:
Journal of Physical Organic Chemistry. 7:663-671
A calorimetric method is described for the determination of the hydride affinities, ΔH(R+) of seven dioxolenium ions from the title compounds and also tropylium, trityl and 9-phenyl xanthylium cations by hydride transfer to the carbocations from BH3
Autor:
A E, Meekhof, S M, Freund
Publikováno v:
Journal of biomolecular NMR. 14(1)
In proteins, dynamic mobility is an important feature of structure, stability, and biomolecular recognition. Uniquely sensitive to motion throughout the milli- to picosecond range, rates of transverse relaxation, R2, are commonly obtained for the cha
Autor:
A E, Meekhof, S M, Freund
Publikováno v:
Journal of molecular biology. 286(2)
The energy landscape for the denatured state of a protein provides a key to understanding early folding events. We have attempted to map this landscape for the third fibronectin type III domain from human tenascin (TNfn3), a compact 9.5 kDa beta-sand
Publikováno v:
Biochemistry. 37(22)
Correct selection of domain boundaries is critical for structural analysis of single domains from multimodular proteins. Folding and stability studies of the third fibronectin type III domain from human tenascin (TNfn31-90) have shown that it is mode