Zobrazeno 1 - 10
of 21 488
pro vyhledávání: '"A E, JOHNSON"'
RNA mis‐splicing in children with congenital myotonic dystrophy is associated with physical function
Autor:
Julia M. Hartman, Kobe Ikegami, Marina Provenzano, Kameron Bates, Amanda Butler, Aileen S. Jones, Kiera N. Berggren, Jeanne Dekdebrun, Marnee J. McKay, Jennifer N. Baldwin, Kayla M. D. Cornett, Joshua Burns, Michael Kiefer, Nicholas E. Johnson, Melissa A. Hale, the DMCRN Consortium
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 12, Pp 3175-3191 (2024)
Abstract Objectives Dysregulated RNA alternative splicing is the hallmark of myotonic dystrophy type 1 (DM1). However, the association between RNA mis‐splicing and physical function in children with the most severe form of disease, congenital myoto
Externí odkaz:
https://doaj.org/article/39ea475afc2640619fc2a601ba893d7c
Autor:
John D. Arena, Douglas H. Smith, Ramon Diaz Arrastia, D. Kacy Cullen, Rui Xiao, Jiaxin Fan, Danielle C. Harris, Cillian E. Lynch, Victoria E. Johnson
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Mild traumatic brain injury (mTBI) or concussion is a substantial health problem globally, with up to 15% of patients experiencing persisting symptoms that can significantly impact quality of life. Currently, the diagnosis of mTBI relies on
Externí odkaz:
https://doaj.org/article/865cf888570340b89bcbcc8ee4ccade3
Autor:
Joel S. Burma, Matthew G. Neill, Elizabeth K. S. Fletcher, Brooke E. Dennett, Nathan E. Johnson, Raelyn Javra, James K. Griffiths, Jonathan D. Smirl
Publikováno v:
Experimental Physiology, Vol 109, Iss 12, Pp 2100-2121 (2024)
Abstract There are differences within the literature regarding the upper frequency cut‐off point of the dynamic cerebral autoregulation (CA) high‐pass filter. The projection pursuit regression approach has demonstrated that the upper frequency li
Externí odkaz:
https://doaj.org/article/f5cc0ec1d5814694acff8b09282573f5
Autor:
Bianca L. Myers, Kathryn J. Brayer, Luis E. Paez-Beltran, Estrella Villicana, Matthew S. Keith, Hideaki Suzuki, Jessie Newville, Rebekka H. Anderson, Yunee Lo, Conner M. Mertz, Rahul K. Kollipara, Mark D. Borromeo, Q. Richard Lu, Robert M. Bachoo, Jane E. Johnson, Tou Yia Vue
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Glioblastomas (GBMs) are highly aggressive, infiltrative, and heterogeneous brain tumors driven by complex genetic alterations. The basic-helix-loop-helix (bHLH) transcription factors ASCL1 and OLIG2 are dynamically co-expressed in GBMs; how
Externí odkaz:
https://doaj.org/article/f09687967c2f4c7785ccf9936e989d72
Autor:
Maji Hailemariam, Lauren M. Weinstock, Rodlescia S. Sneed, Brandon Taylor, Patrick W. Corrigan, Jennifer E. Johnson
Publikováno v:
Pilot and Feasibility Studies, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Background Criminal legal system-involved individuals with serious mental illness (SMI) experience more challenges accessing mental health and other community services than those without a history of criminal legal system involvement. A form
Externí odkaz:
https://doaj.org/article/7004ab01cbbb448280b4f41282e91c44
Autor:
Minghui Tan, Xiwen (Simon) Qin, Claire E. Johnson, Lin Xiao, Angus Cook, Jinfeng Ding, Juan Wang
Publikováno v:
BMC Palliative Care, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background The prevalence of dementia is increasing worldwide and many people with the condition require some level of palliative care. However, the trajectories of function and symptom burden in palliative care services at the end of life r
Externí odkaz:
https://doaj.org/article/186606dad9d741edb630f93e8b8579a4
Autor:
Mohammed Nooruzzaman, Katherine E. E. Johnson, Ruchi Rani, Eli J. Finkelsztein, Leonardo C. Caserta, Rosy P. Kodiyanplakkal, Wei Wang, Jingmei Hsu, Maria T. Salpietro, Stephanie Banakis, Joshua Albert, Lars F. Westblade, Claudio Zanettini, Luigi Marchionni, Rosemary Soave, Elodie Ghedin, Diego G. Diel, Mirella Salvatore
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract We investigated the impact of antiviral treatment on the emergence of SARS-CoV-2 resistance during persistent infections in immunocompromised patients (n = 15). All patients received remdesivir and some also received nirmatrelvir-ritonavir (
Externí odkaz:
https://doaj.org/article/359a8d7b87204768a8ba85f87952dbe3
Autor:
Jennifer M. Belus, Natalie E. Johnson, Grace H. Yoon, Nadine Tschumi, Malebanye Lerotholi, Irene Falgas-Bague, Tristan T. Lee, Pearl Letsoela, Jessica F. Magidson, Alain Amstutz, Niklaus D. Labhardt
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background The World Health Organization’s (WHO) Mental Health Gap Action Programme (mhGAP) is a validated intervention that can be provided by non-specialised healthcare workers to individuals with unhealthy alcohol use. However, it typic
Externí odkaz:
https://doaj.org/article/74a01b70b0b9487c9d15f4fb2294cda7
Autor:
Guiyun Wang, Maya Ebrahimi Zanjani, Angus Cook, Yunyun Dai, Minghui Tan, Xinwen Simon Qin, Claire E. Johnson, Jinfeng Ding
Publikováno v:
BMC Palliative Care, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Most people diagnosed with dementia live and die in community settings. This study aimed to: (i) describe the palliative care needs of patients with dementia at commencement of community palliative care; (ii) compare palliative ca
Externí odkaz:
https://doaj.org/article/bb87da68a7644e9ebb31bcb9e5277d14
Autor:
Dave P. Onorato, Mark W. Cunningham, Mark Lotz, Marc Criffield, David Shindle, Annette Johnson, Bambi C. F. Clemons, Colin P. Shea, Melody E. Roelke-Parker, Warren E. Johnson, Brett T. McClintock, Kristine L. Pilgrim, Michael K. Schwartz, Madan K. Oli
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Genetic rescue—an increase in population fitness following the introduction of new alleles—has been proven to ameliorate inbreeding depression in small, isolated populations, yet is rarely applied as a conservation tool. A lingering ques
Externí odkaz:
https://doaj.org/article/088e990bf097407e97185ff42748e656