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The expression of the glutamate re-uptake transporter excitatory amino acid transporter 1 (EAAT1) in the normal human CNS and in motor neurone disease: an immunohistochemical study

Autor: Anne E. Fray, M Steward, Mark R. Cookson, Paul G. Ince, Steven J. Banner, Pamela J. Shaw

Publikováno v: Neuroscience. 109:27-44

A monoclonal antibody to excitatory amino acid transporter 1 (EAAT1) has been generated which robustly stains paraffin-embedded, formaldehyde-fixed as well as snap-frozen human post-mortem brain tissue. We have used this antibody to map the distribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b61b64cd6738ead7cc432d6dbc62c16
https://doi.org/10.1016/s0306-4522(01)00437-7

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Glutamine synthetase activity and expression are not affected by the development of motor neuronopathy in the G93A SOD-1/ALS mouse

Autor: Pamela J. Shaw, Mark R. Cookson, Susan Dempster, Rebecca Williams, Anne E. Fray

Publikováno v: Molecular Brain Research. 94:131-136

The expression and activity of the enzyme glutamine synthetase (GS) were examined in the G93A/SOD-1 transgenic mouse model of progressive motor neuronopathy to investigate the mechanisms underlying degeneration of the motor neurones. Clinical signs a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e8562f25963bb25c29f58d3ace77de
https://doi.org/10.1016/s0169-328x(01)00228-5

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The expression of the glial glutamate transporter protein EAAT2 in motor neuron disease: an immunohistochemical study

Autor: Ian D. Milton, Mark R. Cookson, Steven J. Banner, Pamela J. Shaw, Philip A. Usher, Paul G. Ince, Anne E. Fray

Publikováno v: European Journal of Neuroscience. 10:2481-2489

Emerging evidence suggests that a disturbance of the glutamate neurotransmitter system may be a contributory factor to motor neuron injury in motor neuron disease. Previous autoradiographic and immunoblotting studies have suggested that there may be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1812e7a17713a3e3cdea8653894539ee
https://doi.org/10.1046/j.1460-9568.1998.00273.x

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Extracellular glucose turnover in the striatum of unanaesthetized rats measured by quantitative microdialysis

Autor: Anne E. Fray, Marianne Fillenz, Martyn G. Boutelle

Publikováno v: The Journal of Physiology. 504:721-726

1. Steady-state and time-resolved quantitative microdialysis was used to measure dialysate concentration, extracellular concentration and the in vivo recovery of glucose in rat striatum. 2. The extracellular concentration of glucose, determined by th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2cd42c3a7e42a4486fb8b2b37b702d
https://doi.org/10.1111/j.1469-7793.1997.721bd.x

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Ultra-Deepwater and Unconventional Natural Gas and Other Petroleum Resources

Autor: Russell E. Fray

RPSEA is currently in its first year of performance under contract DE-AC26-07NT42677, Ultra-Deepwater and Unconventional Natural Gas and Other Petroleum Resources Program Administration. Progress continues to be made in establishing the program admin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69d9658cbb37cbfb7e241fe2a9a19e8d
https://doi.org/10.2172/909177

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Physical and mechanical behavior of electron-beam irradiated and ethylene oxide sterilized multiblock polyester

Autor: M E, Fray, A, Bartkowiak, P, Prowans, J, Slonecki

Publikováno v: Journal of materials science. Materials in medicine. 11(11)

The effect of two sterilization treatments (electron-beam radiation and ethylene oxide gas) on the structure and mechanical properties of a multiblock copolymer were investigated to establish the effects of the sterilizing procedures on potential bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3e6e91e126d74da5aa00d3eb5323c5b
https://pubmed.ncbi.nlm.nih.gov/15348082

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Changes in motor cortex activation after recovery from spinal cord inflammation

Autor: M C Stein, Steven C. Cramer, Peter Riskind, Bruce R. Rosen, Robert A. Parker, E Fray, A. Tievsky, Van J. Wedeen

Publikováno v: Multiple sclerosis (Houndmills, Basingstoke, England). 7(6)

Diseases of the spinal cord are associated with reactive changes in cerebral cortex organization. Many studies in this area have examined spinal cord conditions not associated with recovery, making it difficult to consider the value of these cortical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef15e16a7835140e84051f6d60f4434
https://pubmed.ncbi.nlm.nih.gov/11795457

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