GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection.

Autor: Juan M Ortiz Wilczyñski, Cinthia M Olexen, Andrea E Errasti, Mirta Schattner, Carla V Rothlin, Jorge Correale, Eugenio A Carrera Silva

Publikováno v: PLoS Pathogens, Vol 16, Iss 12, p e1009176 (2020)

Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are known to modulate the severity a

Externí odkaz: https://doaj.org/article/1e5b86274b5c4e95a7c7920372f4e2dc

Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi.

Autor: Chantal Reigada, Edward A Valera-Vera, Melisa Sayé, Andrea E Errasti, Carla C Avila, Mariana R Miranda, Claudio A Pereira

Publikováno v: PLoS Neglected Tropical Diseases, Vol 11, Iss 3, p e0005472 (2017)

Polyamines are essential compounds to all living organisms and in the specific case of Trypanosoma cruzi, the causative agent of Chagas disease, they are exclusively obtained through transport processes since this parasite is auxotrophic for polyamin

Externí odkaz: https://doaj.org/article/31e4abbe1b7b4a12aef8db606edfb6d2

Peer Review #3 of 'Epitope-based chimeric peptide vaccine design against S, M and E proteins of SARS-CoV-2, the etiologic agent of COVID-19 pandemic: an in silico approach (v0.2)'

Autor: E Errasti-Murugarren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::319851dacc7829a613216bf262586caa
https://doi.org/10.7287/peerj.9572v0.2/reviews/3

Junin Virus Triggers Macrophage Activation and Modulates Polarization According to Viral Strain Pathogenicity

Autor: Aída Oryza López Ortiz, Víctor Romanowski, Andrea E. Errasti, Juan Pablo Gorgojo, María Florencia Ferrer, Eugenio Antonio Carrera Silva, Ricardo Martín Gómez, María Eugenia Rodríguez, Pablo Javier Thomas, Nancy Charo

Publikováno v: Frontiers in Immunology, Vol 10 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Immunology
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

The New World arenavirus Junin (JUNV) is the etiological agent of Argentine hemorrhagic fever (AHF). Previous studies of human macrophage infection by the Old-World arenaviruses Mopeia and Lassa showed that while the non-pathogenic Mopeia virus repli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32607f60f886d5b42fe5ed6fede99a08
https://www.frontiersin.org/article/10.3389/fimmu.2019.02499/full

Structural Properties of Macrodontain I, a Cysteine Protease from Pseudananas macrodontes (Morr.) Harms (Bromeliaceae)

Autor: Bruno Maras, Alejandra Ester Rotelli, Claudia L. Natalucci, Laura M. I. López, Néstor O. Caffini, Adriana Brullo, María E. Errasti, Sebastián A. Trejo

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

The primary structure of macrodontain I, a peptidase from Pseudananas macrodontes fruits, was determined using Edman's degradation. The enzyme is a non-glycosylated peptidase composed by 213 amino acids with a calculated molecular weight of 23,486.18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbd6ebfc6d11ea6d073c2da7db16d42
http://link.springer.com/10.1007/s12010-018-2725-3