Zobrazeno 1 - 10
of 1 080
pro vyhledávání: '"A E, Dobson"'
Autor:
R. Mohindra, L. E. Dobson, D. Schlosshan, P. Khan, B. Campbell, M. Garbi, B. Chambers, J. B. Chambers
Publikováno v:
Echo Research and Practice, Vol 11, Iss 1, Pp 1-10 (2024)
Abstract Background Outpatient care for patients with heart valve disease (HVD) is best provided by valve clinics delivered by specialists. Modern day practice in the United Kingdom (UK) is currently poorly understood and has not been evaluated for n
Externí odkaz:
https://doaj.org/article/ebdc4296cce24635b3d65833fce34049
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Despite significant advances in immune checkpoint blockade (ICB), immunosuppression mediated by tumor-associated myeloid cells (TAMCs) poses a major barrier to cancer immunotherapy. In addition, while immunogenic cell death (ICD) provides a
Externí odkaz:
https://doaj.org/article/bdd41061df664c3ba88533a3b50f245e
Autor:
Thomas P. Craven, Pei G. Chew, Laura E. Dobson, Miroslawa Gorecka, Martine Parent, Louise A. E. Brown, Christopher E. D. Saunderson, Arka Das, Amrit Chowdhary, Nicholas Jex, David M. Higgins, Erica Dall’Armellina, Eylem Levelt, Dominik Schlosshan, Peter P. Swoboda, Sven Plein, John P. Greenwood
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 25, Iss 1, Pp 1-17 (2023)
Abstract Background When feasible, guidelines recommend mitral valve repair (MVr) over mitral valve replacement (MVR) to treat primary mitral regurgitation (MR), based upon historic outcome studies and transthoracic echocardiography (TTE) reverse rem
Externí odkaz:
https://doaj.org/article/a60fe25d253940788c580e76c997d697
Autor:
Wuji Zhang, Brendon Y. Chua, Kevin J. Selva, Lukasz Kedzierski, Thomas M. Ashhurst, Ebene R. Haycroft, Suzanne K. Shoffner-Beck, Luca Hensen, David F. Boyd, Fiona James, Effie Mouhtouris, Jason C. Kwong, Kyra Y. L. Chua, George Drewett, Ana Copaescu, Julie E. Dobson, Louise C. Rowntree, Jennifer R. Habel, Lilith F. Allen, Hui-Fern Koay, Jessica A. Neil, Matthew J. Gartner, Christina Y. Lee, Patiyan Andersson, Sadid F. Khan, Luke Blakeway, Jessica Wisniewski, James H. McMahon, Erica E. Vine, Anthony L. Cunningham, Jennifer Audsley, Irani Thevarajan, Torsten Seemann, Norelle L. Sherry, Fatima Amanat, Florian Krammer, Sarah L. Londrigan, Linda M. Wakim, Nicholas J. C. King, Dale I. Godfrey, Laura K. Mackay, Paul G. Thomas, Suellen Nicholson, Kelly B. Arnold, Amy W. Chung, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Thi H. O. Nguyen, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The immune response to SARS-CoV-2 infection is variable but has been linked to prognosis and the development of severe immunopathology. Here the authors assess a range of immune parameters in both peripheral blood and respiratory samples, providing a
Externí odkaz:
https://doaj.org/article/3dbf74c705f948919beba2c6dc7dada4
Autor:
Tiago R. Ferreira, Ehud Inbar, Jahangheer Shaik, Brendan M. Jeffrey, Kashinath Ghosh, Deborah E. Dobson, Stephen M. Beverley, David Sacks
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Genetic exchange between different Leishmania strains in the sand fly vector has been experimentally demonstrated and is supported by population genetic studies. In nature, opportunities for Leishmania interstrain mating are restricted to fl
Externí odkaz:
https://doaj.org/article/e411654cf8044b90ba50e2c8e4780d56
Autor:
Therese Woodring, Colin N. Dewey, Lucas Dos Santos Dias, Xin He, Hannah E. Dobson, Marcel Wüthrich, Bruce Klein
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104934- (2022)
Summary: Memory T cells underpin vaccine-induced immunity but are not yet fully understood. To distinguish features of memory cells that confer protective immunity, we used single cell transcriptome analysis to compare antigen-specific CD4+T cells re
Externí odkaz:
https://doaj.org/article/79de89eeb6af4dca8e37a56c8143f1ce
Autor:
Marcel Wüthrich, Hannah E. Dobson, Cleison Ledesma Taira, Uju Joy Okaa, Lucas dos Santos Dias, Marcos Isidoro-Ayza, Nikolai Petrovsky, Bruce S. Klein
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT The development of effective vaccines against fungal infections requires the induction of protective, pathogen-specific cell-mediated immune responses. Here, we asked whether combination adjuvants based on delta inulin (Advax) formulated wit
Externí odkaz:
https://doaj.org/article/56e44bbade2946e58ea31d694fa2764b
Autor:
Cheng Xu, Hannah E. Dobson, Mengjie Yu, Wang Gong, Xiaoqi Sun, Kyung Soo Park, Andrew Kennedy, Xingwu Zhou, Jin Xu, Yao Xu, Andrew W. Tai, Yu Leo Lei, James J. Moon
Publikováno v:
Journal of Controlled Release. 357:84-93
Autor:
Tonie E. Rocke, Brock Kingstad-Bakke, Marcel Wüthrich, Ben Stading, Rachel C. Abbott, Marcos Isidoro-Ayza, Hannah E. Dobson, Lucas dos Santos Dias, Kevin Galles, Julia S. Lankton, Elizabeth A. Falendysz, Jeffrey M. Lorch, J. Scott Fites, Jaime Lopera-Madrid, J. Paul White, Bruce Klein, Jorge E. Osorio
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract White-nose syndrome (WNS) caused by the fungus, Pseudogymnoascus destructans (Pd) has killed millions of North American hibernating bats. Currently, methods to prevent the disease are limited. We conducted two trials to assess potential WNS
Externí odkaz:
https://doaj.org/article/6d8f3b480a084707931474796061c861
Autor:
Lucas Dos Santos Dias, Hannah E Dobson, Brock Kingstad Bakke, Gregory C Kujoth, Junfeng Huang, Elaine M Kohn, Cleison Ledesma Taira, Huafeng Wang, Nitin T Supekar, J Scott Fites, Daisy Gates, Christina L Gomez, Charles A Specht, Stuart M Levitz, Parastoo Azadi, Lingjun Li, Marulasiddappa Suresh, Bruce S Klein, Marcel Wüthrich
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009324 (2021)
The development of safe subunit vaccines requires adjuvants that augment immunogenicity of non-replicating protein-based antigens. Current vaccines against infectious diseases preferentially induce protective antibodies driven by adjuvants such as al
Externí odkaz:
https://doaj.org/article/fc7f3feb47ae4cc8a5f6edd4c6048362