Zobrazeno 1 - 10
of 2 665
pro vyhledávání: '"A E, Dixon"'
Autor:
Zhi-Qiang Xu, Slobodan Jergic, Allen T. Y. Lo, Alok C. Pradhan, Simon H. J. Brown, James C. Bouwer, Harshad Ghodke, Peter J. Lewis, Gökhan Tolun, Aaron J. Oakley, Nicholas E. Dixon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Ring-shaped DNA sliding clamps are essential for DNA replication and genome maintenance. Clamps need to be opened and chaperoned onto DNA by clamp loader complexes (CLCs). Detailed understanding of the mechanisms by which CLCs open and place
Externí odkaz:
https://doaj.org/article/9e8880c9aa2c40dbb2212545d9c48737
Autor:
Resa M. Jones, Jennifer G. Andrews, Alexandra F. Dalton, Brian E. Dixon, Bari J. Dzomba, Shane I. Fernando, Kristen M. Pogreba-Brown, Miguel Reina Ortiz, Vinita Sharma, Nicole Simmons, Sharon H. Saydah, for the Track PCC Study Group
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Track PCC includes five geographic surveillance sites to conduct standardized population-based surveillance to estimate and track Post-COVID Conditions (PCC) by age, sex, race/ethnicity, geographic area, severity of initial infect
Externí odkaz:
https://doaj.org/article/c8c372674dd942d79412572b9c3cd19c
Autor:
Paul Y. Takahashi, MD, MPH, Euijung Ryu, PhD, Katherine S. King, MS, Rachel E. Dixon, BA, Julie C. Porcher, MS, Philip H. Wheeler, Chung Il Wi, MD, Young J. Juhn, MD, MPH
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 2, Pp 259-269 (2024)
Objective: To identify geographic locations with high numbers of medically attended falls (ie, hotspots) by older adults and to test the associations between fall hotspots and resident/housing characteristics. Patients and Methods: In this cohort stu
Externí odkaz:
https://doaj.org/article/bc0ffbde8d9445c5abfc330484952988
Autor:
Daniel P. Riggins, Jill Inderstrodt, John Price, Shaun J. Grannis, Titus Schleyer, Jennifer Crago, Stephen O'Brien, Brian E. Dixon
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
Indiana faces significant challenges in maternal and infant health, ranking 45th worst in infant mortality with a rate of 6.5 deaths per 1,000 live-births, and 21st in stillbirths. Indiana further has the 3rd highest rate of maternal mortality with 4
Externí odkaz:
https://doaj.org/article/bf9224c509db4f1da8ac68cc9293a7ae
Autor:
Maartje Westhoff, Silvia G. del Villar, Taylor L. Voelker, Phung N. Thai, Heather C. Spooner, Alexandre D. Costa, Padmini Sirish, Nipavan Chiamvimonvat, Eamonn J. Dickson, Rose E. Dixon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cardiac dysfunction is a hallmark of aging in humans and mice. Here we report that a two-week treatment to restore youthful Bridging Integrator 1 (BIN1) levels in the hearts of 24-month-old mice rejuvenates cardiac function and substantially
Externí odkaz:
https://doaj.org/article/b0477fcf8cac487d9b9bce149837c365
Autor:
Marcos N. Barcellona, Tara Ní Néill, Fergal J. O’Brien, James E. Dixon, Caroline M. Curtin, Conor T. Buckley
Publikováno v:
Advanced NanoBiomed Research, Vol 4, Iss 7, Pp n/a-n/a (2024)
Back pain is a global epidemiological and socioeconomic problem affecting up to 80% of people at some stage during their life and is often due to degeneration of the intervertebral disc (IVD). Therapies aimed at restoring the intradiscal space have p
Externí odkaz:
https://doaj.org/article/59d2e2835cd3478b85ce7e0126b73ff1
Autor:
Haojia Wu, Eryn E. Dixon, Qiao Xuanyuan, Juanru Guo, Yasuhiro Yoshimura, Chitnis Debashish, Anezka Niesnerova, Hao Xu, Morgane Rouault, Benjamin D. Humphreys
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Emerging spatially resolved transcriptomics technologies allow for the measurement of gene expression in situ at cellular resolution. We apply direct RNA hybridization-based in situ sequencing (dRNA HybISS, Cartana part of 10xGenomics) to co
Externí odkaz:
https://doaj.org/article/227cd3e034c34e63baed1ad49c0fbc42
Mosaic loss of Y chromosome is associated with aging and epithelial injury in chronic kidney disease
Autor:
Parker C. Wilson, Amit Verma, Yasuhiro Yoshimura, Yoshiharu Muto, Haikuo Li, Nicole P. Malvin, Eryn E. Dixon, Benjamin D. Humphreys
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-27 (2024)
Abstract Background Mosaic loss of Y chromosome (LOY) is the most common chromosomal alteration in aging men. Here, we use single-cell RNA and ATAC sequencing to show that LOY is present in the kidney and increases with age and chronic kidney disease
Externí odkaz:
https://doaj.org/article/551e6c9819dd473baf7dff771a4e8c17
Publikováno v:
ACS Omega, Vol 9, Iss 4, Pp 5014-5023 (2024)
Externí odkaz:
https://doaj.org/article/ffefe7a5989e4c12b3cfbfd407b980a3
Autor:
Jeong Han Lee, Maria C. Perez-Flores, Seojin Park, Hyo Jeong Kim, Yingying Chen, Mincheol Kang, Jennifer Kersigo, Jinsil Choi, Phung N. Thai, Ryan L. Woltz, Dolores Columba Perez-Flores, Guy Perkins, Choong-Ryoul Sihn, Pauline Trinh, Xiao-Dong Zhang, Padmini Sirish, Yao Dong, Wayne Wei Feng, Isaac N. Pessah, Rose E. Dixon, Bernd Sokolowski, Bernd Fritzsch, Nipavan Chiamvimonvat, Ebenezer N. Yamoah
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The inner ear is the hub where hair cells (HCs) transduce sound, gravity, and head acceleration stimuli to the brain. Hearing and balance rely on mechanosensation, the fastest sensory signals transmitted to the brain. The mechanoelectrical t
Externí odkaz:
https://doaj.org/article/2460730132124905aa50c50a2faffa24