Zobrazeno 1 - 10 of 74 pro vyhledávání: '"A E, Crozier"'
1
Akademický článek
Relationship between self-stigma about alcohol dependence and severity of alcohol drinking and craving
Autor: Susan Persky, Lorenzo Leggio, Madeline E Crozier, Mehdi Farokhnia, Brenda Curtis
Publikováno v: BMJ Mental Health, Vol 26, Iss 1 (2023)
Background The correlates and consequences of stigma surrounding alcohol use are complex. Alcohol use disorder (AUD) is typically accompanied by self-stigma, due to numerous factors, such as shame, guilt and negative stereotypes. Few studies have emp
Externí odkaz: https://doaj.org/article/05415f57e49b4535b5de39a5cc717d5f
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2
Akademický článek
Differential association between the GLP1R gene variants and brain functional connectivity according to the severity of alcohol use
Autor: Mehdi Farokhnia, Samantha J. Fede, Erica N. Grodin, Brittney D. Browning, Madeline E. Crozier, Melanie L. Schwandt, Colin A. Hodgkinson, Reza Momenan, Lorenzo Leggio
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Growing evidence suggests that the glucagon-like peptide-1 (GLP-1) system is involved in mechanisms underlying alcohol seeking and consumption. Accordingly, the GLP-1 receptor (GLP-1R) has begun to be studied as a potential pharmacotherapeut
Externí odkaz: https://doaj.org/article/3d80a92a9efe45a9bf8ea0eb75a58636
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4
Understanding Plea Bargaining in a New Progressive DA’s Office: How Line Prosecutors Understand and Implement Progressive Goals Through Plea Decisions
Autor: Catherine A. Grodensky, William E. Crozier, Elizabeth J. Gifford, Brandon L. Garrett
Publikováno v: Criminal Justice and Behavior. 50:429-453
Plea deals resolve the vast majority of prosecuted criminal cases in the U.S. legal system. Prosecutors hold disproportionate power in plea bargaining and have been blamed for driving punitiveness and racial disparities. Progressive prosecutors aim t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e63ec913feb8e88773e91b5dd1cbe804
https://doi.org/10.1177/00938548221140356
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6
JNK signaling during IL-3–mediated differentiation contributes to the c-kit–potentiated allergic inflammatory capacity of mast cells
Autor: Natalie J Hicks, Robert W E Crozier, Adam J MacNeil
Publikováno v: Journal of Leukocyte Biology.
Mast cells are leukocytes that mediate various aspects of immunity and drive allergic hypersensitivity pathologies. Mast cells differentiate from hematopoietic progenitor cells in a manner that is largely IL-3 dependent. However, molecular mechanisms
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cda09ec44f0de24f83b219026a411981
https://doi.org/10.1093/jleuko/qiad050
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8
Targeting glycogen synthase kinase 3 with CHIR99021 negatively regulates allergen-induced mast cell activation
Autor: Robert W. E. Crozier, Val A. Fajardo, Adam J. MacNeil
Publikováno v: European journal of immunology.
Mast cells are granulated immune sentinels responsible for allergic inflammation. Allergen-induced FcεRI-signaling leads to rapid degranulation in the early-phase and sustained production and release of pro-inflammatory mediators in the late-phase.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d419bfc01f3b42f9480b0cfb99d076
https://pubmed.ncbi.nlm.nih.gov/36349527
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9
Zika Virus Replication in a Mast Cell Model is Augmented by Dengue Virus Antibody-Dependent Enhancement and Features a Selective Immune Mediator Secretory Profile
Autor: Jeremia M. Coish, Robert W. E. Crozier, John S. Schieffelin, Jens R. Coorssen, Fiona F. Hunter, Adam J. MacNeil
Publikováno v: Microbiology spectrum. 10(4)
Antibodies generated against one dengue serotype can enhance infection of another by a phenomenon called antibody-dependent enhancement (ADE). Additionally, antigenic similarities between Zika and dengue viruses can promote Zika virus infection by wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0382fd10308d5d923197e7f4fd2bb854
https://pubmed.ncbi.nlm.nih.gov/35862953
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10
The glucagon-like peptide-1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a post-mortem brain study
Autor: Mehdi Farokhnia, Brittney D. Browning, Madeline E. Crozier, Hui Sun, Fatemeh Akhlaghi, Lorenzo Leggio
Publikováno v: Addiction biologyREFERENCES. 27(5)
Growing evidence suggests that the glucagon-like peptide-1 (GLP-1) system modulates alcohol seeking and consumption, and GLP-1 analogues may represent novel pharmacotherapies for alcohol use disorder (AUD). Accordingly, it is important to understand
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ff20ac13ec76854d424f4c062450b7
https://pubmed.ncbi.nlm.nih.gov/36001436
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