Zobrazeno 1 - 10
of 40
pro vyhledávání: '"A E, Bukatina"'
Publikováno v:
Biophysics. 51:789-792
We assessed the effect of phalloidin, known to detach nebulin from actin in skeletal myofibrils, on the isometric force of skinned lamprey cardiac muscle, which has nebulin in amounts comparable to that in skeletal muscle. In contrast to mammalian ca
Publikováno v:
Journal of Applied Physiology. 87:1861-1876
A relatively simple method is presented for incorporating cross-bridge mechanisms into a muscle model. The method is based on representing force in a half sarcomere as the product of the stiffness of all parallel cross bridges and their average disto
Publikováno v:
Journal of Muscle Research and Cell Motility. 19:515-523
Phalloidin, an F-actin stabilizing peptide, is known to enhance Ca2+ responsiveness in skinned cardiac muscle. Here we studied the effects of dethiophalloidin (DTPH), a phalloidin derivative which, binding much more weakly to F-actin, has no phalloid
Autor:
Eileen M. McMahon, T R Lombari, Marek Belohlavek, Anna E Bukatina, Naomi M. Gades, Minako Katayama, P Jiamsripong
Publikováno v:
Laboratory animals. 47(2)
Pharmacokinetics of drugs may differ between small and large mammals (including humans); therefore, drug testing in animal models must be carefully designed. Sprague–Dawley rats were used in cardiac experiments, during which the lopinavir concentra
Autor:
Anna E Bukatina, Ronald J. Marler, Minako Katayama, Theresa R. Lombari, Marek Belohlavek, Qing Wu, Panupong Jiamsripong, Eileen M. McMahon
Publikováno v:
Ultrasound in medicinebiology. 38(9)
Myocardial reperfusion following ischemia may paradoxically cause additional injury, including microvascular damage and edema. These structural alterations augment tissue echogenicity, which is measurable by ultrasonic integrated backscatter (IB). We
Publikováno v:
Neuroscience and Behavioral Physiology. 23:83-89
As many as 88 patients with Alzheimer's type senile dementia were followed up. Of these, 28 patients suffered from marked and 60 from unpronounced dementia. 74 patients received amiridine and 14 made up a control group. Amiridine was administered per
Publikováno v:
The FASEB Journal. 21
Publikováno v:
Biofizika. 51(5)
The effect of phalloidin, an agent detaching nebulin from actin in skeletal muscle, on the isometric force in lamprey skinned cardiac muscle, which has nebulin in amounts comparable to that in skeletal muscle, has been studied. We found that, unlike
Autor:
A E, Bukatina, G S, Sik
Publikováno v:
Biofizika. 48(6)
The contraction of myofibrils is regulated by the coordinated action of Ca2+ and myosin cross-bridges. Phallotoxins induce a variety of specific changes in myofibrillar functioning and are therefore a potentially valuable tool for muscle research. Th
Publikováno v:
Tsitologiia. 42(1)
Phalloidin, a toxic product of the mushroom Amanita phalloides, binds specifically to F-actin resulting in strong stabilization of F-actin structure (for review, see; Wieland, 1986). Binding to a specific site on the muscle thin filament F-actin, pha