Zobrazeno 1 - 10
of 27
pro vyhledávání: '"A Denise R, Garcia"'
Autor:
Kathryn M. Markey, Jillian C. Saunders, Jana Smuts, Catherine R. von Reyn, A. Denise R. Garcia
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The past 15–20 years has seen a remarkable shift in our understanding of astrocyte contributions to central nervous system (CNS) function. Astrocytes have emerged from the shadows of neuroscience and are now recognized as key elements in a broad ar
Externí odkaz:
https://doaj.org/article/a55d6dc9a62a4cd7a45af8421fd205ae
Publikováno v:
Neural Development, Vol 17, Iss 1, Pp 1-13 (2022)
Abstract Background The molecular signaling pathway, Sonic hedgehog (Shh), is critical for the proper development of the central nervous system. The requirement for Shh signaling in neuronal and oligodendrocyte development in the developing embryo ar
Externí odkaz:
https://doaj.org/article/26943b443ba645a1be4d93983d76ae49
Autor:
Rachana Deven Somaiya, Katelyn Stebbins, Ellen C Gingrich, Hehuang Xie, John N Campbell, A Denise R Garcia, Michael A Fox
Publikováno v:
eLife, Vol 11 (2022)
Axons of retinal ganglion cells (RGCs) play critical roles in the development of inhibitory circuits in visual thalamus. We previously reported that RGC axons signal astrocytes to induce the expression of fibroblast growth factor 15 (FGF15), a motoge
Externí odkaz:
https://doaj.org/article/1d2f6e71b5cc4324a02c742702e24f05
Autor:
Steven A Hill, Andrew S Blaeser, Austin A Coley, Yajun Xie, Katherine A Shepard, Corey C Harwell, Wen-Jun Gao, A Denise R Garcia
Publikováno v:
eLife, Vol 8 (2019)
Astrocytes have emerged as integral partners with neurons in regulating synapse formation and function, but the mechanisms that mediate these interactions are not well understood. Here, we show that Sonic hedgehog (Shh) signaling in mature astrocytes
Externí odkaz:
https://doaj.org/article/11e26469fdde4824846a42dedc8da8f8
Autor:
A. Denise R. Garcia
Publikováno v:
Cells, Vol 10, Iss 6, p 1353 (2021)
The Sonic hedgehog (Shh) molecular signaling pathway is well established as a key regulator of neurodevelopment. It regulates diverse cellular behaviors, and its functions vary with respect to cell type, region, and developmental stage, reflecting th
Externí odkaz:
https://doaj.org/article/18f82c14869a4364b6cb9b55feae5118
Publikováno v:
Cellular and Molecular Life Sciences
Astrocytes are complex cells that perform a broad array of essential functions in the healthy and injured nervous system. The recognition that these cells are integral components of various processes, including synapse formation, modulation of synapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8f1d2712802db78c7ccc6b64f205ba
https://doi.org/10.1007/s00018-020-03668-8
https://doi.org/10.1007/s00018-020-03668-8
Autor:
A. Denise R. Garcia, Rebecca A. Ihrie, W. Todd Farmer, Corey C. Harwell, Young-Goo Han, Jason W. Triplett
Publikováno v:
The Journal of Neuroscience. 38:9338-9345
Sonic Hedgehog (SHH) signaling has been most widely known for its role in specifying region and cell-type identity during embryonic morphogenesis. This mini-review accompanies a 2018 SFN mini-symposium that addresses an emerging body of research focu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35bb96ff6e41f0e22ddf4a849f955fa
https://doi.org/10.1523/jneurosci.1662-18.2018
https://doi.org/10.1523/jneurosci.1662-18.2018
Publikováno v:
Journal of Cell Biology. 217:3141-3159
Neurons are large and long lived, creating high needs for regulating protein turnover. Disturbances in proteostasis lead to aggregates and cellular stress. We characterized the behavior of the short-lived dendritic membrane proteins Nsg1 and Nsg2 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52fbbc7315d6da3d812c13fc0d547b2d
https://doi.org/10.1083/jcb.201711039
https://doi.org/10.1083/jcb.201711039