Zobrazeno 1 - 10
of 1 857
pro vyhledávání: '"A Dempfle"'
Autor:
Brigitte Dahmen, Ingar Zielinski-Gussen, Manuel Föcker, Freia Hahn, Tanja Legenbauer, Ulf Thiemann, Astrid Dempfle, Beate Herpertz-Dahlmann
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background New treatment approaches are urgently needed to improve the prognosis of children and adolescents with anorexia nervosa (AN). Recently, the feasibility of multidisciplinary home treatment that strongly involves the patients’ par
Externí odkaz:
https://doaj.org/article/83576e20760a480e8a8d9e8debe2d328
Autor:
Christoph Rogmans, Jan Dittrich, Emily Hamm, Jörg Paul Weimer, David Holthaus, Norbert Arnold, Inken Flörkemeier, Nicolai Maass, Peer Jansen, Astrid Dempfle, Dirk O. Bauerschlag, Nina Hedemann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Acquired or de novo resistance to poly (ADP-ribose) polymerase inhibitors (PARPi) is a major challenge to ovarian cancer treatment. Therefore, strategies to overcome PARPi resistance are critical to improve prognosis. The purpose of this stu
Externí odkaz:
https://doaj.org/article/4291c4464e794268896575de7315d9cc
Autor:
Nathalie Rohmann, Theresa Geese, Samantha Nestel, Kristina Schlicht, Corinna Geisler, Kathrin Türk, Fynn Brix, Julia Jensen-Kroll, Tobias Demetrowitsch, Corinna Bang, Andre Franke, Wolfgang Lieb, Dominik M. Schulte, Karin Schwarz, Anne-Kathrin Ruß, Arunabh Sharma, Stefan Schreiber, Astrid Dempfle, Matthias Laudes
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Biomedical and lifestyle factors in Western populations have significantly shifted in recent decades, influencing public health and contributing to the increasing prevalence of non-communicable diseases (NCDs) that share inflammat
Externí odkaz:
https://doaj.org/article/b4bc7d08819b401190511382d1aa1a9c
Autor:
Inken Flörkemeier, Lisa K. Antons, Jörg P. Weimer, Nina Hedemann, Christoph Rogmans, Sandra Krüger, Regina Scherließ, Astrid Dempfle, Norbert Arnold, Nicolai Maass, Dirk O. Bauerschlag
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract In vitro, spheroid models have become well established in cancer research because they can better mimic certain characteristics of in vivo tumours. However, interaction with the tumour microenvironment, such as cancer-associated fibroblasts,
Externí odkaz:
https://doaj.org/article/64babe67f1b14d97a499efdf4b30fa15
Autor:
Christine Eimer, Natalia Urbaniak, Astrid Dempfle, Tobias Becher, Dirk Schädler, Norbert Weiler, Inéz Frerichs
Publikováno v:
Perioperative Medicine, Vol 13, Iss 1, Pp 1-9 (2024)
Abstract Background Postoperative respiratory failure is the most frequent complication in postsurgical patients. The purpose of this study is to assess whether pulmonary function testing in high-risk patients during preoperative assessment detects p
Externí odkaz:
https://doaj.org/article/dfb323a249ee4b76abdc55512d839ed9
Autor:
Nadia Andrea Andreani, Arunabh Sharma, Brigitte Dahmen, Hannah E. Specht, Nina Mannig, Vanessa Ruan, Lara Keller, John F. Baines, Beate Herpertz-Dahlmann, Astrid Dempfle, Jochen Seitz
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTThere is mounting evidence regarding the role of gut microbiota in anorexia nervosa (AN). Previous studies have reported that patients with AN show dysbiosis compared to healthy controls (HCs); however, the underlying mechanisms are unclear,
Externí odkaz:
https://doaj.org/article/31f065d21dd74643b8251c513934e545
Autor:
Milda Aleknonytė-Resch, Joanne Trinh, Hampton Leonard, Sylvie Delcambre, Elsa Leitão, Dongbing Lai, Semra Smajić, Avi Orr-Urtreger, Avner Thaler, Cornelis Blauwendraat, Arunabh Sharma, Mary B. Makarious, Jonggeol Jeff Kim, Julie Lake, Pegah Rahmati, Sandra Freitag-Wolf, Philip Seibler, Tatiana Foroud, Andrew B. Singleton, The International Parkinson Disease Genomics Consortium, Anne Grünewald, Frank Kaiser, Christine Klein, Michael Krawczak, Astrid Dempfle
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract The effects of one genetic factor upon Parkinson’s disease (PD) risk may be modified by other genetic factors. Such gene-gene interaction (G×G) could explain some of the ‘missing heritability’ of PD and the reduced penetrance of known
Externí odkaz:
https://doaj.org/article/eab9e702433b4666b815d44862487080
Autor:
Yiran Zheng, Luisa Sophie Rajcsanyi, Triinu Peters, Astrid Dempfle, Stefan A. Wudy, Johannes Hebebrand, Anke Hinney
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Recent studies reported an impact of the melanocortin 3 receptor (MC3R) on the regulation of body weight, linear growth and puberty timing. Previously, allele p.44Ile of a frequent non-synonymous variant (NSV) p.Val44Ile was reported to be a
Externí odkaz:
https://doaj.org/article/9ceac8f0bab34ca0bdc41e5842e0e6fa
Publikováno v:
European Psychiatry, Vol 67 (2024)
Abstract Background A large increase in the rate of hospitalizations for adolescents and children with anorexia nervosa (AN) was observed during the coronavirus disease (COVID-19) pandemic. It is still not clear whether this was a temporary effect o
Externí odkaz:
https://doaj.org/article/13656c47245843b0b7c5e1a834c0e527
Autor:
Rahul Unni, Nadia Andrea Andreani, Marie Vallier, Silke S. Heinzmann, Jan Taubenheim, Martina A. Guggeis, Florian Tran, Olga Vogler, Sven Künzel, Jan-Bernd Hövener, Philip Rosenstiel, Christoph Kaleta, Astrid Dempfle, Daniel Unterweger, John F. Baines
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTInflammatory bowel disease (IBD) is a persistent inflammatory condition that affects the gastrointestinal tract and presents significant challenges in its management and treatment. Despite the knowledge that within-host bacterial evolution oc
Externí odkaz:
https://doaj.org/article/7e7f9818193443be9d74abb5dd5dbde3