Zobrazeno 1 - 10
of 603
pro vyhledávání: '"A Dean Sherry"'
Autor:
Xiaojing Wang, Keisuke Ishimatsu, Junjie Li, Xiaodong Wen, Weijun Ou, Arnida Anwar, Jaideep Chaudhary, Masaya Takahashi, A Dean Sherry, Ian R Corbin
Publikováno v:
Hepatic Oncology, Vol 11, Iss 1 (2024)
Aim: The aim of this study was to assess the utility of weighted amide proton transfer (APTw) MRI in three different rodent models of hepatocellular carcinoma (HCC).Methods: APTw MRI was evaluated in models of diethylnitrosamine (DEN) induced HCC, N1
Externí odkaz:
https://doaj.org/article/398cbb479cd0478e8a4bf543065b03bd
Autor:
Osamu Togao, Chase W Kessinger, Gang Huang, Todd C Soesbe, Koji Sagiyama, Ivan Dimitrov, A Dean Sherry, Jinming Gao, Masaya Takahashi
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77019 (2013)
Amide proton transfer (APT) imaging is one of the chemical exchange saturation transfer (CEST) imaging methods which images the exchange between protons of free tissue water and the amide groups (-NH) of endogenous mobile proteins and peptides. Previ
Externí odkaz:
https://doaj.org/article/84258062c8a5470cb391381dc8576b46
Autor:
Ana Christina L Opina, Ketan B Ghaghada, Piyu Zhao, Garry Kiefer, Ananth Annapragada, A Dean Sherry
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27370 (2011)
Lanthanide DOTA-tetraglycinate (LnDOTA-(gly)₄⁻) complexes contain four magnetically equivalent amide protons that exchange with protons of bulk water. The rate of this base catalyzed exchange process has been measured using chemical exchange satu
Externí odkaz:
https://doaj.org/article/0beb3bfdcf144c6abbc6ddf9cf8faaa6
Autor:
Eul Hyun Suh, Carlos F. G. C. Geraldes, Sara Chirayil, Brandon Faubert, Raul Ayala, Ralph J. DeBerardinis, A. Dean Sherry
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-10 (2021)
Abstract Background Excessive lactate production, a hallmark of cancer, is largely formed by the reduction of pyruvate via lactate dehydrogenase (LDH) to l-lactate. Although d-lactate can also be produced from glucose via the methylglyoxal pathway in
Externí odkaz:
https://doaj.org/article/aa4e4f7bf1184b3ea910f6a8758f378c
Publikováno v:
Communications Chemistry, Vol 3, Iss 1, Pp 1-9 (2020)
Dynamic nuclear polarization coupled with 15N magnetic resonance imaging can afford quantitative imaging of biologically important metal ions. Here the authors prepare 15N-enriched, d 6-deuterated tris(2-pyridylmethyl)amine as an MRI sensor for freel
Externí odkaz:
https://doaj.org/article/85a455602e0d447bb7b48667db506d76
Autor:
Bibek Thapa, Eul Hyun Suh, Daniel Parrott, Pooyan Khalighinejad, Gaurav Sharma, Sara Chirayil, A. Dean Sherry
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
An imaging method for detecting β-cell function in real-time in the rodent pancreas could provide new insights into the biological mechanisms involving loss of β-cell function during development of type 2 diabetes and for testing of new drugs desig
Externí odkaz:
https://doaj.org/article/9d3efc7e2cc640f99933a0f46e2e6e3e
Autor:
Veronica Clavijo Jordan, Catherine D. G. Hines, Liza T. Gantert, Shubing Wang, Stacey Conarello, Christian Preihs, Sara Chirayil, Michael Klimas, Jeffrey L. Evelhoch, A. Dean Sherry
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Non-invasive beta cell function measurements may provide valuable information for improving diabetes diagnostics and disease management as the integrity and function of pancreatic beta cells have been found to be compromised in Type-1 and Type-2 diab
Externí odkaz:
https://doaj.org/article/fc97c59679444ff39cabae396fbd4b0b
Autor:
Shiuhwei Chen, ZhiJiang Huang, Harrison Kidd, Min Kim, Eul Hyun Suh, Shangkui Xie, Ebrahim H. Ghazvini Zadeh, Yan Xu, A. Dean Sherry, Philipp E. Scherer, Wen-hong Li
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Appropriate insulin secretion is essential for maintaining euglycemia, and impairment or loss of insulin release represents a causal event leading to diabetes. There have been extensive efforts of studying insulin secretion and its regulation using a
Externí odkaz:
https://doaj.org/article/3cc8fee9653e4262885de5dece07ea1e
Publikováno v:
International Journal of Biological Macromolecules. 217:27-41
The global HIV/AIDS epidemic still currently affects approximately 38 million individuals globally. The protease enzyme of the human immunodeficiency virus is a major drug target in antiviral therapy, however, under the influence of reverse transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af87cde2b32b4a2c7284a303f877e870
https://doi.org/10.1016/j.ijbiomac.2022.07.033
https://doi.org/10.1016/j.ijbiomac.2022.07.033
Autor:
Daniel Parrott, Eul Hyun Suh, Pooyan Khalighinejad, Veronica Clavijo Jordan, Ivan Arreola, Su-Tang Lo, A. Dean Sherry
Publikováno v:
Molecular Imaging and Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f97a0bdaf93061a42085de38044c3a34
https://doi.org/10.1007/s11307-023-01821-w
https://doi.org/10.1007/s11307-023-01821-w