Zobrazeno 1 - 10
of 611
pro vyhledávání: '"A David Burden"'
Autor:
A. David Burden
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 4, Pp 1067-1069 (2024)
Externí odkaz:
https://doaj.org/article/ecc480b35a944c198880f4b2cadd6687
Autor:
A. David Burden, Robert Bissonnette, Alexander A. Navarini, Masamoto Murakami, Akimichi Morita, Thomas Haeufel, Binqi Ye, Frank Baehner, Tadashi Terui
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 10, Pp 2279-2297 (2023)
Abstract Introduction We evaluated the anti-interleukin-36 receptor antibody spesolimab in patients with moderate-to-severe palmoplantar pustulosis (PPP). Methods This phase IIb trial comprised a loading dose period to week (W) 4, then maintenance do
Externí odkaz:
https://doaj.org/article/6d6cb5a5aa4948e883bc5a0968cd7992
Autor:
Teresa Tsakok, Jake Saklatvala, Theo Rispens, Floris C. Loeff, Annick de Vries, Michael H. Allen, Ines A. Barbosa, David Baudry, Tejus Dasandi, Michael Duckworth, Freya Meynell, Alice Russell, Anna Chapman, Sandy McBride, Kevin McKenna, Gayathri Perera, Helen Ramsay, Raakhee Ramesh, Kathleen Sands, Alexa Shipman, the Biomarkers of Systemic Treatment Outcomes in Psoriasis (BSTOP) Study Group, A. David Burden, Christopher E.M. Griffiths, Nick J. Reynolds, Richard B. Warren, Satveer Mahil, Jonathan Barker, Nick Dand, Catherine Smith, Michael A. Simpson
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Targeted biologic therapies can elicit an undesirable host immune response characterized by the development of antidrug antibodies (ADA), an important cause of treatment failure. The most widely used biologic across immune-mediated diseases is adalim
Externí odkaz:
https://doaj.org/article/b7bce9e049e346049f02cc279904382b
Autor:
Gareth T. Jones, Gary J. Macfarlane, Karen Forrest Keenan, Paul McNamee, Aileen R. Neilson, Stefan Siebert, A. David Burden, Lesley Kay, Philip S. Helliwell
Publikováno v:
BMC Rheumatology, Vol 5, Iss 1, Pp 1-9 (2021)
Abstract Background Psoriatic arthritis (PsA) presents a unique clinical challenge. Affecting joints, skin, nails, and other organs, it is associated with various comorbidities and has a significant impact on quality of life, social participation and
Externí odkaz:
https://doaj.org/article/01ff878112a24d0fae046487510eae0a
Autor:
Liz Falconer, David Burden, Rosamund Cleal, Ralph Hoyte, Phillip Phelps, Neil Slawson, Nicola Snashall, Kate Welham
Publikováno v:
Virtual Archaeology Review, Vol 11, Iss 23, Pp 50-62 (2020)
This paper describes and discusses creating and evaluating a virtual reality simulation of Avebury Stone Circle and Henge complex as it might have appeared and sounded circa 2300 BCE. Avebury is a Neolithic heritage site in the UK which is part of th
Externí odkaz:
https://doaj.org/article/d70a931ea8c941698a332a9756a4e83e
Autor:
Shan Pan, Teresa Tsakok, Nick Dand, Dagan O. Lonsdale, Floris C. Loeff, Karien Bloem, Annick deVries, David Baudry, Michael Duckworth, Satveer Mahil, Angela Pushpa‐Rajah, Alice Russell, Ali Alsharqi, Gabrielle Becher, Ruth Murphy, Shyamal Wahie, Andrew Wright, Christopher E.M. Griffiths, Nick J. Reynolds, Jonathan Barker, Richard B. Warren, A. David Burden, Theo Rispens, Joseph F. Standing, Catherine H. Smith, on behalf of the BADBIR Study Group, the BSTOP Study Group, the PSORT Consortium
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 2, Pp 400-409 (2020)
Variation in response to biologic therapy for inflammatory diseases, such as psoriasis, is partly driven by variation in drug exposure. Real‐world psoriasis data were used to develop a pharmacokinetic/pharmacodynamic (PK/PD) model for the first‐l
Externí odkaz:
https://doaj.org/article/619cb5f9e3a54af0aff4b70a0b891c13
Autor:
Suzie Cro, Victoria Cornelius, Francesca Capon, Jonathan Barker, David Burden, Christopher Griffiths, Helen Jane Lachmann, Helen McAteer, Prakash Patel, Andrew Pink, Nick Reynolds, Richard Warren, Catherine Smith
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 9, Iss 2 (2022)
Background: Palmoplantar pustulosis is a rare, debilitating, chronic skin disease involving the hands and feet, and there are limited treatment options. Mechanistic findings suggest that interleukin 1 may be a pathogenic driver. Objective: To determi
Externí odkaz:
https://doaj.org/article/edf7d69042de4f0d9cf28e6a9dc050ca
Autor:
Hamida Turki, Akimichi Morita, Min Zheng, Tsen-Fang Tsai, Siew Eng Choon, Mark G Lebwohl, Slaheddine Marrakchi, A David Burden, Alexander A Navarini, Jinhua Xu, Sushmita Rajeswari, Hongjie Deng, Kay Tetzlaff, Christian Thoma, Hervé Bachelez
Publikováno v:
BMJ Open, Vol 11, Iss 3 (2021)
Introduction Generalized pustular psoriasis (GPP) is a rare, potentially life-threatening disease characterised by recurrent flares of widespread neutrophilic aseptic skin pustular eruption. Despite the availability of approved biologics for GPP in J
Externí odkaz:
https://doaj.org/article/0e3c0e8c9db14d56a3bd5916c2666e43
Autor:
A David Burden
Publikováno v:
Expert Review of Clinical Immunology. 19:473-481
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbb0c1915d62a1a12e0bd0c8f2b180e
https://doi.org/10.1080/1744666x.2023.2195165
https://doi.org/10.1080/1744666x.2023.2195165
Autor:
Christos Petridis, Alexander A. Navarini, Nick Dand, Jake Saklatvala, David Baudry, Michael Duckworth, Michael H. Allen, Charles J. Curtis, Sang Hyuck Lee, A. David Burden, Alison Layton, Veronique Bataille, Andrew E. Pink, The Acne Genetic Study Group, Isabelle Carlavan, Johannes J. Voegel, Timothy D. Spector, Richard C. Trembath, John A. McGrath, Catherine H. Smith, Jonathan N. Barker, Michael A. Simpson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Acne vulgaris is a chronic inflammation of the skin, the genetic basis of which is incompletely understood. Here, Petridis et al. perform GWAS and meta-analysis for acne in 26,722 individuals and identify 12 novel risk loci that implicate structure a
Externí odkaz:
https://doaj.org/article/452ea8192e3a4a489db21942afed2d37