Zobrazeno 1 - 10
of 372
pro vyhledávání: '"A D De Silva"'
Autor:
Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Roshan Liyanage, Dhammika Amaratunga, Yetrib Hathout, Harry W. M. Steinbusch, Ashwin Dalal, Eric P. Hoffman, K. Ranil D. de Silva
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract Background The phenotype of Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) patients is determined by the type of DMD gene variation, its location, effect on reading frame, and its size. The primary objective of this in
Externí odkaz:
https://doaj.org/article/c4163d83d1134daf81f028ae6456712e
Autor:
Emily R. Ko, Megan E. Reller, L. Gayani Tillekeratne, Champica K. Bodinayake, Cameron Miller, Thomas W. Burke, Ricardo Henao, Micah T. McClain, Sunil Suchindran, Bradly Nicholson, Adam Blatt, Elizabeth Petzold, Ephraim L. Tsalik, Ajith Nagahawatte, Vasantha Devasiri, Matthew P. Rubach, Venance P. Maro, Bingileki F. Lwezaula, Wasantha Kodikara-Arachichi, Ruvini Kurukulasooriya, Aruna D. De Silva, Danielle V. Clark, Kevin L. Schully, Deng Madut, J. Stephen Dumler, Cecilia Kato, Renee Galloway, John A. Crump, Geoffrey S. Ginsburg, Timothy D. Minogue, Christopher W. Woods
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Diagnostic limitations challenge management of clinically indistinguishable acute infectious illness globally. Gene expression classification models show great promise distinguishing causes of fever. We generated transcriptional data for a 2
Externí odkaz:
https://doaj.org/article/6b810e23001a49d88802db46e9e5c9d3
Autor:
Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Darshana Sirisena, Harsha Gunasekara, Athula Dissanayake, Sunethra Senanayake, Ajantha Keshavaraj, Yetrib Hathout, Harry W.M. Steinbusch, Chandra Mohan, Ashwin Dalal, Eric Hoffman, K.Ranil D de Silva
Publikováno v:
IBRO Neuroscience Reports, Vol 14, Iss , Pp 146-153 (2023)
Background: In this article, the authors discuss how they utilized the genetic mutation data in Sri Lankan Duchenne muscular dystrophy (DMD), Spinal muscular atrophy (SMA), Spinocerebellar ataxia (SCA) and Huntington’s disease (HD) patients and com
Externí odkaz:
https://doaj.org/article/4ac8bd1ca053427ab5295e8573dda7c8
Autor:
Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Pulasthi Dissanayaka, Isuru Gunarathne, Dhammika Amaratunga, Roshan Liyanage, Sunethra Senanayaka, Saraji Wijesekara, Hemal H. Gunasekara, Kamala Vanarsa, Jessica Castillo, Yetrib Hathout, Ashwin Dalal, Harry W.M. Steinbusch, Eric Hoffman, Chandra Mohan, K. Ranil D. de Silva
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18530- (2023)
Introduction: Documented Duchenne Muscular Dystrophy (DMD) biomarkers are confined to Caucasians and are poor indicators of cognitive difficulties and neuropsychological alterations. Materials and methods: This study correlates serum protein signatur
Externí odkaz:
https://doaj.org/article/ea7f989c48ed46f8ad872ba9e802e1d3
Publikováno v:
Sri Lanka Journal of Medicine, Vol 31, Iss 1, Pp 28-35 (2022)
Background: Anemia during pregnancy is a significant public health concern. Sri Lankan maternal healthcare system adopted free provision of iron and folic acid supplementation to all its pregnant women since several decades, to mitigate the high prev
Externí odkaz:
https://doaj.org/article/ac1c6ec8a69f48d2b6c80adec295311a
Autor:
H. Abeygoonawardena, H. Jayasinghearachchi, T. Senaratne, P. Jayasekera, D. Nakkawita, N. Mubarak, U. Kulasekera, P. Kawyangana, D. Govindapala, A. D. De Silva
Publikováno v:
Sri Lankan Journal of Infectious Diseases, Vol 13, Iss 1, Pp E40 1-9 (2023)
We report a family cluster of six members who tested positive for SARS-CoV-2 infection in April 2021 at University Hospital, Kotelawala Defence University, Sri Lanka. Samples from three members were subjected to Next Generation Sequencing (NGS) and a
Externí odkaz:
https://doaj.org/article/56bfe0b5812b44b39bd44e34c36c70d9
Autor:
N. P. Weerasinghe, C. K. Bodinayake, W. M. D. G. B. Wijayaratne, I. V. Devasiri, N. J. Dahanayake, M. R. P. Kurukulasooriya, M. Premamali, T. Sheng, B. P. Nicholson, H. A. Ubeysekera, A. D. de Silva, T. Østbye, C. W. Woods, L. G. Tillekeratne, A De S Nagahawatte
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background The Southern Province of Sri Lanka is endemic with dengue, with frequent outbreaks and occurrence of severe disease. However, the economic burden of dengue is poorly quantified. Therefore, we conducted a cost analysis to assess th
Externí odkaz:
https://doaj.org/article/218f9ace9ad5442f95ac97b97d819063
Autor:
Himali S. Jayasinghearachchi, Thilini A. Muthugama, Jayanthi Masakorala, Upeksha S. Kulasekara, Kumari Jayaratne, D. A. Dasun N. Jayatunga, Aruna D. De Silva, Enoka M. Corea
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2023)
Burkholderia pseudomallei is the causative agent of the potentially fatal infection, melioidosis. This study provides the first evidence for the presence of B. pseudomallei in soil and water in Sri Lanka. Targeted sampling of soil and natural water s
Externí odkaz:
https://doaj.org/article/9fe182e0891141269ccc925519680540
Autor:
Himali S. Jayasinghearachchi, Vaithehi R. Francis, Harindra D. Sathkumara, Shivankari Krishnananthasivam, Jayanthi Masakorala, Thilini Muthugama, Aruna D. De Silva, Enoka M. Corea
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 11, Pp 2955-2957 (2021)
A melioidosis case cluster of 10 blood culture–positive patients occurred in eastern Sri Lanka after an extreme weather event. Four infections were caused by Burkholderia pseudomallei isolates of sequence type 594. Whole-genome analysis showed that
Externí odkaz:
https://doaj.org/article/cd98ed3175af4911bfabf557c4572695
Autor:
Champica K Bodinayake, Ajith DeS Nagahawatte, Vasantha Devasiri, Niroshana J Dahanayake, Gaya B Wijayaratne, Nayani P Weerasinghe, Madureka Premamali, Tianchen Sheng, Bradley P Nicholson, Harshanie A Ubeysekera, Ruvini Mp Kurukulasooriya, Aruna D de Silva, Truls Østbye, Christopher W Woods, L Gayani Tillekeratne
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 5, p e0010498 (2022)
[This corrects the article DOI: 10.1371/journal.pntd.0010091.].
Externí odkaz:
https://doaj.org/article/4ff8b40f28904b33af93e08a20e9ab34