The Angelina Jolie effect: Contralateral risk-reducing mastectomy trends in patients at increased risk of breast cancer

Autor: James Harvey, Shaunak Chatterjee, Julie Wisely, Andrew D. Baildam, Richard J Johnson, L Barr, John Murphy, Sacha Howell, Nicola Barnes, D. Gareth Evans, Anthony Howell, James Hodson, Lyndsey Highton, Cliona C. Kirwan, Narendra Nath Basu, Ashu Gandhi

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports

Contralateral risk-reducing mastectomy (CRRM) rates have tripled over the last 2 decades. Reasons for this are multi-factorial, with those harbouring a pathogenic variant in the BRCA1/2 gene having the greatest survival benefit. On May 14th, 2013, An

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3124c1604da62f9fcf66340bd814c1a
https://doi.org/10.1038/s41598-021-82654-x

Reply: Novel Approach for Risk-Reducing Mastectomy: First-Stage Implant Placement and Subsequent Second-Stage Mastectomy

Autor: Geok Hoon, Lim, Andrew D, Baildam

Publikováno v: Plastic and reconstructive surgery. 144(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::866890f22a83ca14027b2c01586189b2
https://pubmed.ncbi.nlm.nih.gov/31246845

Long-Term Evaluation of Women Referred to a Breast Cancer Family History Clinic (Manchester UK 1987–2020)

Autor: Rosemary Greenhalgh, Sally Cole, Fiona Lalloo, Penelope Hopwood, Andrew D Baildam, Mary Pegington, Jenny Affen, Andrew Maurice, D. Gareth Evans, Anthony J. Maxwell, Anthony Howell, Julie Wisely, Lester Barr, Julia Wiseman, Sacha J Howell, Elaine F. Harkness, Ashu Gandhi, Andrea Wilding, Mary Wilson, David P. French, Michelle Harvie, Susan M. Astley

Publikováno v: Cancers, Vol 12, Iss 3697, p 3697 (2020)
Cancers
Volume 12
Issue 12
Howell, A, Gandhi, A, Howell, S, Wilson, M, Maxwell, A, Astley, S, Harvie, M, Pegington, M, Barr, L, Baildam, A, Harkness, E, Hopwood, P, Wisely, J, Wilding, A, Greenhalgh, R, Affen, J, Maurice, A, Cole, S, Wiseman, J, Lalloo, F, French, D P & Evans, D G 2020, ' Long-term evaluation of women referred to a breast cancer family history clinic (Manchester UK 1987–2020) ', Cancers, vol. 12, no. 12, 3697, pp. 1-19 . https://doi.org/10.3390/cancers12123697

Clinics for women concerned about their family history of breast cancer are widely established. A Family History Clinic was set-up in Manchester, UK, in 1987 in a Breast Unit serving a population of 1.8 million. In this review, we report the outcome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d9c80028e80f160fbae08ca67ae341
https://doi.org/10.3390/cancers12123697

Contralateral mastectomy improves survival in women with BRCA1/2-associated breast cancer

Autor: Anthony Howell, Gary L Ross, Iain Buchan, Andrew D Baildam, Sarah L Ingham, Fiona Lalloo, D. Gareth Evans

Publikováno v: Breast Cancer Research and Treatment. 140:135-142

BRCA1/2 mutation carriers with breast cancer are at high risk of contralateral disease. Such women often elect to have contralateral risk-reducing mastectomy (CRRM) to reduce the likelihood of recurrence. This study considers whether CRRM improves ov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0309e9f139d574ec64b0d8fe8eb11d99
https://doi.org/10.1007/s10549-013-2583-1

Cyclooxygenase-2 Inhibition Does Not Improve the Reduction in Ductal Carcinoma In situ Proliferation with Aromatase Inhibitor Therapy: Results of the ERISAC Randomized Placebo-Controlled Trial

Autor: Andrew D Baildam, Pamela J. Flint, Kwok-Leung Cheung, Sue Grassby, Julie Morris, Göran Landberg, O. Young, Nigel J Bundred, Lorraine Turner, Lorna Renshaw, R. Johnson, A. Cramer, J Michael Dixon, Lester Barr

Publikováno v: Clinical Cancer Research. 16:1605-1612

Purpose: Tamoxifen reduces risk of recurrence after breast conservation surgery for ductal carcinoma in situ (DCIS), but no data exists on the effectiveness of aromatase inhibitors for DCIS. Cyclooxygenase-2 (COX-2) is overexpressed in DCIS, represen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979e61252af4239e7e3162c621d45270
https://doi.org/10.1158/1078-0432.ccr-09-1623