Zobrazeno 1 - 10
of 1 472
pro vyhledávání: '"A D, WELCH"'
Autor:
Maria C. Virgilio, Barkha Ramnani, Thomas Chen, W. Miguel Disbennett, Jay Lubow, Joshua D. Welch, Kathleen L. Collins
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract HIV-1 Vpr promotes efficient spread of HIV-1 from macrophages to T cells by transcriptionally downmodulating restriction factors that target HIV-1 Envelope protein (Env). Here we find that Vpr induces broad transcriptomic changes by targetin
Externí odkaz:
https://doaj.org/article/9f0bc0d6e95e41a78274cf91ba1605a0
Publikováno v:
SAGE Open Medicine, Vol 12 (2024)
Background: Many youth saw a rise in body mass index and obesity during the COVID-19 pandemic associated with virtual schooling and a lack of physical exercise options due to lockdown orders. However, the impact of the worldwide COVID-19 pandemic on
Externí odkaz:
https://doaj.org/article/78f26f39976a4747979c7bb8cc22618a
Autor:
Yuki Matsushita, Jialin Liu, Angel Ka Yan Chu, Chiaki Tsutsumi-Arai, Mizuki Nagata, Yuki Arai, Wanida Ono, Kouhei Yamamoto, Thomas L. Saunders, Joshua D. Welch, Noriaki Ono
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract The bone marrow contains various populations of skeletal stem cells (SSCs) in the stromal compartment, which are important regulators of bone formation. It is well-described that leptin receptor (LepR)+ perivascular stromal cells provide a m
Externí odkaz:
https://doaj.org/article/5e0cb48692ce48ddaed400c4096968cd
Autor:
Yuki Matsushita, Angel Ka Yan Chu, Chiaki Tsutsumi-Arai, Shion Orikasa, Mizuki Nagata, Sunny Y. Wong, Joshua D. Welch, Wanida Ono, Noriaki Ono
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
In endochondral bone development, bone-forming osteoblasts and bone marrow stromal cells have dual origins in the fetal cartilage and its surrounding perichondrium. Here they show that perichondrial cells are destined to become adipocyte-biased strom
Externí odkaz:
https://doaj.org/article/161d2898b0a04e75bd7d5ef44721fc27
Publikováno v:
Journal of Medical Education and Curricular Development, Vol 10 (2023)
Objective The effectiveness of lecture-based (LB) formats for residency education has recently been challenged as the gold standard. Studies suggest a flipped classroom (FC) lecture improves resident satisfaction, but evidence that showing improved k
Externí odkaz:
https://doaj.org/article/98a3ea1a6dda46039d394be7601d492a
Publikováno v:
Insects, Vol 15, Iss 1, p 38 (2024)
Grassland ecosystems of the Northern Plains have changed substantially since European settlement began in the latter half of the 19th century. This has led to significant changes to the dung-dwelling arthropod community in the region. As humans conti
Externí odkaz:
https://doaj.org/article/2852f0557506488b8ec3155c67dada1e
Autor:
Robert R. Ehrman, Bryce X. Bredell, Nicholas E. Harrison, Mark J. Favot, Brian D. Haber, Robert D. Welch, Philip D. Levy, Robert L. Sherwin
Publikováno v:
The Ultrasound Journal, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Septic cardiomyopathy was recognized more than 30 years ago, but the early phase remains uncharacterized as no existing studies captured patients at the time of Emergency Department (ED) presentation, prior to resuscitation. Thera
Externí odkaz:
https://doaj.org/article/f272af1bb11c43bbbad54e331403758b
Autor:
Gina M. Borgo, Thomas P. Burke, Cuong J. Tran, Nicholas T. N. Lo, Patrik Engström, Matthew D. Welch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Pathogenic Rickettsia species are arthropod-borne, obligate intracellular bacteria that invade host cells, replicate in the cell cytosol, and spread from cell to cell. Here, Borgo et al. identify a Rickettsia phospholipase enzyme that is important fo
Externí odkaz:
https://doaj.org/article/76fc7169ff2a4a5fa9121ffd75dec244
Autor:
Norbert S. Hill, Matthew D. Welch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Mycobacterium marinum, a close relative of Mycobacterium tuberculosis, polymerizes host actin at the bacterial surface to drive intracellular movement and cell-to-cell spread during infection. Here, Hill & Welch identify an M. marinum surface protein
Externí odkaz:
https://doaj.org/article/15e5e84ee37d4f1d89a37393022c3624
Autor:
April R. Kriebel, Joshua D. Welch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Single-cell genomic technologies present unique data integration challenges. Here the authors introduce an integrative nonnegative matrix factorization algorithm that incorporates features unshared between datasets when performing dataset integration
Externí odkaz:
https://doaj.org/article/a0dbf8d380e14acc8048ffbe00c321c3