Zobrazeno 1 - 10
of 515
pro vyhledávání: '"A D, Stiles"'
Autor:
Elizabeth A. Pogue, Alexander New, Kyle McElroy, Nam Q. Le, Michael J. Pekala, Ian McCue, Eddie Gienger, Janna Domenico, Elizabeth Hedrick, Tyrel M. McQueen, Brandon Wilfong, Christine D. Piatko, Christopher R. Ratto, Andrew Lennon, Christine Chung, Timothy Montalbano, Gregory Bassen, Christopher D. Stiles
Publikováno v:
npj Computational Materials, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Discovery of novel materials is slow but necessary for societal progress. Here, we demonstrate a closed-loop machine learning (ML) approach to rapidly explore a large materials search space, accelerating the intentional discovery of supercon
Externí odkaz:
https://doaj.org/article/0f288a1057e2432db4f684a6df63cc72
Autor:
Axel Hoffmann, Shriram Ramanathan, Julie Grollier, Andrew D. Kent, Marcelo J. Rozenberg, Ivan K. Schuller, Oleg G. Shpyrko, Robert C. Dynes, Yeshaiahu Fainman, Alex Frano, Eric E. Fullerton, Giulia Galli, Vitaliy Lomakin, Shyue Ping Ong, Amanda K. Petford-Long, Jonathan A. Schuller, Mark D. Stiles, Yayoi Takamura, Yimei Zhu
Publikováno v:
APL Materials, Vol 10, Iss 7, Pp 070904-070904-24 (2022)
Neuromorphic computing approaches become increasingly important as we address future needs for efficiently processing massive amounts of data. The unique attributes of quantum materials can help address these needs by enabling new energy-efficient de
Externí odkaz:
https://doaj.org/article/4ef8d29d955f499fbe0f4e2c16f98a8f
Autor:
Hamed Vakili, Mohammad Nazmus Sakib, Samiran Ganguly, Mircea Stan, Matthew W. Daniels, Advait Madhavan, Mark D. Stiles, Avik W. Ghosh
Publikováno v:
IEEE Journal on Exploratory Solid-State Computational Devices and Circuits, Vol 6, Iss 2, Pp 107-115 (2020)
Race logic is a relative timing code that represents information in a wavefront of digital edges on a set of wires in order to accelerate dynamic programming and machine learning algorithms. Skyrmions, bubbles, and domain walls are mobile magnetic co
Externí odkaz:
https://doaj.org/article/9d21d41a4c7b4fae83f060d4bbf19433
Autor:
Zachary J. Reitman, Brenton R. Paolella, Guillaume Bergthold, Kristine Pelton, Sarah Becker, Robert Jones, Claire E. Sinai, Hayley Malkin, Ying Huang, Leslie Grimmet, Zachary T. Herbert, Yu Sun, Jessica L. Weatherbee, John A. Alberta, John F. Daley, Orit Rozenblatt-Rosen, Alexandra L. Condurat, Kenin Qian, Prasidda Khadka, Rosalind A. Segal, Daphne Haas-Kogan, Mariella G. Filbin, Mario L. Suva, Aviv Regev, Charles D. Stiles, Mark W. Kieran, Liliana Goumnerova, Keith L. Ligon, Alex K. Shalek, Pratiti Bandopadhayay, Rameen Beroukhim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Pilocytic astrocytoma is a low-grade pediatric glioma, characterized by a single BRAF rearrangement. Here, Reitman and colleagues use single-cell RNA sequencing to reveal molecular hallmarks of the disease that might be targeted therapeutically.
Externí odkaz:
https://doaj.org/article/751f4dad2db84b0f893ba0445a18b1bd
Publikováno v:
ACM Journal on Emerging Technologies in Computing Systems. 19:1-24
The movement of large quantities of data during the training of a deep neural network presents immense challenges for machine learning workloads, especially those based on future functional memories deployed to store network models. As the size of ne
Autor:
Eshini Panditharatna, Joana G. Marques, Tingjian Wang, Maria C. Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V. Dharia, Deyao Li, Samantha E. Hoffman, Guillaume Kugener, McKenzie L. Shaw, Hafsa M. Mire, Olivia A. Hack, Joshua M. Dempster, Caleb Lareau, Lingling Dai, Logan H. Sigua, Michael A. Quezada, Ann-Catherine J. Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Federica Piccioni, John G. Doench, David E. Root, Jamie N. Anastas, Kristen L. Jones, Amy Saur Conway, Sylwia Stopka, Michael S. Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P. Jerome, Nathan D. Mathewson, Sirano Dhe-Paganon, Mario L. Suvà, Angel M. Carcaboso, Cinzia Lavarino, Jaume Mora, Quang-De Nguyen, Keith L. Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y.R. Agar, Kimberly Stegmaier, Charles D. Stiles, Michelle Monje, Todd R. Golub, Jun Qi, Mariella G. Filbin
Publikováno v:
Cancer Discovery. :OF1-OF26
Diffuse midline gliomas are uniformly fatal pediatric central nervous system cancers that are refractory to standard-of-care therapeutic modalities. The primary genetic drivers are a set of recurrent amino acid substitutions in genes encoding histone
Autor:
Jing Zhou, An-Chi Tien, John A. Alberta, Scott B. Ficarro, Amelie Griveau, Yu Sun, Janhavee S. Deshpande, Joseph D. Card, Meghan Morgan-Smith, Wojciech Michowski, Rintaro Hashizume, C. David James, Keith L. Ligon, William D. Snider, Peter Sicinski, Jarrod A. Marto, David H. Rowitch, Charles D. Stiles
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3167-3177 (2017)
During development of the vertebrate CNS, the basic helix-loop-helix (bHLH) transcription factor Olig2 sustains replication competence of progenitor cells that give rise to neurons and oligodendrocytes. A pathological counterpart of this developmenta
Externí odkaz:
https://doaj.org/article/7fb9e82920cf40d1898b5c51de91b9b8
Autor:
K. Michael Salerno, Janna Domenico, Nam Q. Le, Christopher D. Stiles, Ilia A. Solov’yov, Carlos F. Martino
Publikováno v:
Journal of Chemical Information and Modeling. 62:4191-4199
Reactive oxygen species (ROS) exert a wide range of biological effects from beneficial regulatory function to deleterious oxidative stress. The electron transfer flavoprotein (ETF) is ubiquitous to life and is associated with aerobic metabolism and R
Autor:
Brian D. Hoskins, Matthew W. Daniels, Siyuan Huang, Advait Madhavan, Gina C. Adam, Nikolai Zhitenev, Jabez J. McClelland, Mark D. Stiles
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Neural networks based on nanodevices, such as metal oxide memristors, phase change memories, and flash memory cells, have generated considerable interest for their increased energy efficiency and density in comparison to graphics processing units (GP
Externí odkaz:
https://doaj.org/article/9fc6cdecc96e485aa27de89a19bed0ae
Autor:
Mariella G. Filbin, Jun Qi, Todd R. Golub, Michelle Monje, Charles D. Stiles, Kimberly Stegmaier, Nathalie Y.R. Agar, Sameer Agnihotri, Yang Shi, Keith L. Ligon, Quang-De Nguyen, Jaume Mora, Cinzia Lavarino, Angel M. Carcaboso, Mario L. Suvà, Sirano Dhe-Paganon, Nathan D. Mathewson, William P. Jerome, Puspalata Bashyal, Kijun Song, Hyuk-Soo Seo, Yu Liang, Michael S. Regan, Sylwia Stopka, Amy Saur Conway, Kristen L. Jones, Jamie N. Anastas, David E. Root, John G. Doench, Federica Piccioni, Francisca Vazquez, Amy Goodale, Zohra Kalani, Meghan Wyatt, Ann-Catherine J. Stanton, Michael A. Quezada, Logan H. Sigua, Lingling Dai, Caleb Lareau, Joshua M. Dempster, Olivia A. Hack, Hafsa M. Mire, McKenzie L. Shaw, Guillaume Kugener, Samantha E. Hoffman, Deyao Li, Neekesh V. Dharia, Andrew Groves, Alexander Beck, Li Jiang, Ilon Liu, Maria C. Trissal, Tingjian Wang, Joana G. Marques, Eshini Panditharatna
Supplementary Figure from BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f64519af0b30cd43dfae7d183877165
https://doi.org/10.1158/2159-8290.22541865
https://doi.org/10.1158/2159-8290.22541865