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Development of the system for gene therapy of AIDS on the basis of antisense RNAs

Publikováno v: Biopolymers and Cell, Vol 29, Iss 4, Pp 348-353 (2013)

Based on adeno-associated virus derived plasmid construct that are able to synthesize in cells antisense RNAs directed against key genes of HIV. Gematopoietic human cells carrying the created structure, acquired resistance to HIV infection, as eviden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977bbfa83c703e4d32d66b48c1052917
http://biopolymers.org.ua/pdf/en/29/4/348/

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The problem of cord blood banking

Autor: A. D. Shved

Publikováno v: Biopolymers and Cell, Vol 29, Iss 2, Pp 85-98 (2013)

The review considers the literature data on issues of cord blood (CB) banking in different countries and regions. The existing forms of banks are private, mixed and public, the latter is preferred by most clinicians who are experienced in stem cell t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f7397fd459d343a9d8b59bfa9ee27d
http://biopolymers.org.ua/pdf/ru/29/2/085/

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New 1,2,4-triazine bearing compounds: molecular modeling, synthesis and biotesting

Autor: A. D. Shved, L. S. Usenko, M. O. Platonov, O. M. Kostenko, V. V. Negrutska, I. V. Alexeeva, L. G. Palchykovska

Publikováno v: Biopolymers and Cell, Vol 25, Iss 6, Pp 491-499 (2009)
Scopus-Elsevier

Aim. To enlarge a spectrum of biologically active compounds in the series of the 1,2,4-triazino[5,6-b] [1,4]benzothiazine (1,2,4-TBT) derivatives and reveal among them efficient inhibitors of RNA synthesis Methods. The methods of structure optimizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab37b0aa45fe538c6c732c6340ad887d
http://www.biopolymers.org.ua/archive/2009/06/ru/Palchikovskaya.pdf

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New acridone-4-carboxylic acid derivatives as potential inhibitors of Hepatitis C virus infection

Autor: Anna Stankiewicz-Drogoń, Larisa G. Palchykovska, Anna M. Boguszewska-Chachulska, V. G. Kostina, I. V. Alexeeva, A. D. Shved

Publikováno v: Bioorganic & Medicinal Chemistry. 16:8846-8852

A new class of compounds—acridone derivatives—was tested using the direct fluorometric helicase activity assay to determine the inhibitory properties of the derivatives towards the NS3 helicase of Hepatitis C virus (HCV). The compounds were also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fa2bcf2a33fd1cc58c7f7a17afed3b
https://doi.org/10.1016/j.bmc.2008.08.074

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