Zobrazeno 1 - 10
of 1 115
pro vyhledávání: '"A D, Schreiber"'
Autor:
Xiuli Zhang, S. Peter Goedegebuure, Michael Y. Chen, Rashmi Mishra, Felicia Zhang, Yik Yeung Yu, Kartik Singhal, Lijin Li, Feng Gao, Nancy B. Myers, Tammi Vickery, Jasreet Hundal, Michael D. McLellan, Mark A. Sturmoski, Samuel W. Kim, Ina Chen, Jesse T. Davidson, Narendra V. Sankpal, Stephanie Myles, Rama Suresh, Cynthia X. Ma, Ademuyiwa Foluso, Andrea Wang-Gillam, Sherri Davies, Ian S. Hagemann, Elaine R. Mardis, Obi Griffith, Malachi Griffith, Christopher A. Miller, Ted H. Hansen, Timothy P. Fleming, Robert D. Schreiber, William E. Gillanders
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Neoantigen vaccines can induce or enhance highly specific antitumor immune responses with minimal risk of autoimmunity. We have developed a neoantigen DNA vaccine platform capable of efficiently presenting both HLA class I and II
Externí odkaz:
https://doaj.org/article/361f87535f3347da8e2cfda87d75ab59
Autor:
William L. Harrigan, Barbra D. Ferrell, K. Eric Wommack, Shawn W. Polson, Zachary D. Schreiber, Mahdi Belcaid
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background The annotation of protein sequences in public databases has long posed a challenge in molecular biology. This issue is particularly acute for viral proteins, which demonstrate limited homology to known proteins when using alignmen
Externí odkaz:
https://doaj.org/article/11da29dbb5db42a19a182a6b11c4be02
Autor:
Thomas Thisted, F. Donelson Smith, Arnab Mukherjee, Yuliya Kleschenko, Feng Feng, Zhi-Gang Jiang, Timothy Eitas, Kanam Malhotra, Zuzana Biesova, Adejumoke Onumajuru, Faith Finley, Anokhi Cifuentes, Guolin Zhang, Gaëlle H. Martin, Yoshiko Takeuchi, Kader Thiam, Robert D. Schreiber, Edward H. van der Horst
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract VISTA, an inhibitory myeloid-T-cell checkpoint, holds promise as a target for cancer immunotherapy. However, its effective targeting has been impeded by issues such as rapid clearance and cytokine release syndrome observed with previous VIST
Externí odkaz:
https://doaj.org/article/5baa81963d6e484cb872b3eac39edd59
Autor:
T. Forkmann, J. Eimen, L. Plein, I. Höller, L. Böhler, A. Schönfelder, N. Hallensleben, D. Schreiber, L. Paashaus, G. Juckel, T. Teismann, H. Glaesmer, L. Spangenberg
Publikováno v:
Journal of Affective Disorders Reports, Vol 17, Iss , Pp 100822- (2024)
Background: Hopelessness is a transdiagnostically relevant clinical construct, related to depression, post-traumatic stress disorder and suicidality. Economic, valid, and reliable assessment of hopelessness is thus crucial for both research and clini
Externí odkaz:
https://doaj.org/article/f85a136e82c9465d92778da327a9a4ae
Autor:
Roxane Tussiwand, Michael S. Behnke, Nicole M. Kretzer, Gary E. Grajales-Reyes, Theresa L. Murphy, Robert D. Schreiber, Kenneth M. Murphy, L. David Sibley
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Immunity to Toxoplasma gondii at early stages of infection in C57BL/6 mice depends on gamma interferon (IFN-γ) production by NK cells, while at later stages it is primarily mediated by CD8 T cells. We decided to explore the requirement for
Externí odkaz:
https://doaj.org/article/dd378a1387414af696a0707ee5fde62a
Autor:
Kenneth C. Anderson, Lewis C. Cantley, Riccardo Dalla-Favera, Chi Van Dang, Luis A. Diaz, Raymond N. DuBois, Keith T. Flaherty, Philip D. Greenberg, Massimo Loda, Elaine R. Mardis, Elizabeth A. Platz, Michael N. Pollak, Robert D. Schreiber, Lillian L. Siu, Beverly A. Teicher
Publikováno v:
Blood Cancer Discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244050b4a6e289616651da5de7e4e31b
https://doi.org/10.1158/1541-7786.mcr-22-0804
https://doi.org/10.1158/1541-7786.mcr-22-0804
Autor:
M. Fehlings, Y. Simoni, H. L. Penny, E. Becht, C. Y. Loh, M. M. Gubin, J. P. Ward, S. C. Wong, R. D. Schreiber, E. W. Newell
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Immune checkpoint blockade (ICB) therapies can unleash anti-tumour T-cell responses. Here the authors show, by integrating MHC tetramer multiplexing, mass cytometry and high-dimensional analyses, that neoantigen-specific, tumour-infiltrating T cells
Externí odkaz:
https://doaj.org/article/7858136795e54c05b2eaf80fa3fc40f9
Autor:
Tanner M. Johanns, Christopher A. Miller, Connor J. Liu, Richard J. Perrin, Diane Bender, Dale K. Kobayashi, Jian L. Campian, Michael R. Chicoine, Ralph G. Dacey, Jiayi Huang, Edward F. Fritsch, William E. Gillanders, Maxim N. Artyomov, Elaine R. Mardis, Robert D. Schreiber, Gavin P. Dunn
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Neoantigens represent promising targets for personalized cancer vaccine strategies. However, the feasibility of this approach in lower mutational burden tumors like glioblastoma (GBM) remains unknown. We have previously reported the use of an immunog
Externí odkaz:
https://doaj.org/article/8dde9e453942466c919f33fd089ee9d6
Autor:
Kenneth M. Murphy, Theresa L. Murphy, Robert D. Schreiber, Tian-Tian Liu, Jing Chen, Sunkyung Kim, Xiao Huang, Renee Wu, Feiya Ou, Ray A. Ohara, Stephen T. Ferris
As a cell-based cancer vaccine, dendritic cells (DC), derived from peripheral blood monocytes or bone marrow (BM) treated with GM-CSF (GMDC), were initially thought to induce antitumor immunity by presenting tumor antigens directly to host T cells. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5a2af4ebdac0e4bffa3c57265d0a2e
https://doi.org/10.1158/2326-6066.c.6550934.v1
https://doi.org/10.1158/2326-6066.c.6550934.v1
Autor:
Kenneth M. Murphy, Theresa L. Murphy, Robert D. Schreiber, Tian-Tian Liu, Jing Chen, Sunkyung Kim, Xiao Huang, Renee Wu, Feiya Ou, Ray A. Ohara, Stephen T. Ferris
Supplementary Figure from cDC1 Vaccines Drive Tumor Rejection by Direct Presentation Independently of Host cDC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c7fd5f7a32c9a02b70c0c2fe00c605
https://doi.org/10.1158/2326-6066.22545404
https://doi.org/10.1158/2326-6066.22545404