Zobrazeno 1 - 10
of 517
pro vyhledávání: '"A D, Schimmer"'
Autor:
May Chiu, Aaron D. Schimmer, Andre C. Schuh, Aniket Bankar, Guillaume Richard-Carpentier, Hassan Sibai, Karen Yee, Marta Davidson, Steven M. Chan, Vikas Gupta, Dawn Maze
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/c7a90e66b1a74df39d5b68d84be53494
Autor:
Maria Agustina Perusini, Claire Andrews, Eshetu G. Atenafu, Vikas Gupta, Dawn Maze, Andre C. Schuh, Karen WL. Yee, Aniket Bankar, Marta B. Davidson, Guillaume Richard-Carpentier, Steven M. Chan, Jad Sibai, Aaron D. Schimmer, Mark D. Minden, Hassan Sibai
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
ABSTRACTThis retrospective report presents the outcomes and adverse events (AEs) observed in 73 patients aged 60 years or older diagnosed with Philadelphia Chromosome-negative Acute Lymphoblastic Leukemia (Ph-negative ALL) treated with a pediatric-in
Externí odkaz:
https://doaj.org/article/860fe86b5d6c425b93b7c8cf45f165fa
Autor:
Danny V. Jeyaraju, Maryam Alapa, Ann Polonskaia, Alberto Risueño, Prakash Subramanyam, Amit Anand, Kaushik Ghosh, Charalampos Kyriakopoulos, Daiane Hemerich, Rose Hurren, Xiaoming Wang, Marcela Gronda, Aarif Ahsan, Hsiling Chiu, Geethu Thomas, Evan F. Lind, Daniel L Menezes, Aaron D. Schimmer, Patrick R. Hagner, Anita Gandhi, Anjan G. Thakurta
Publikováno v:
Haematologica, Vol 109, Iss 4 (2023)
Oral azacitidine (oral-Aza) treatment results in longer median overall survival (OS) (24.7 vs. 14.8 months in placebo) in patients with acute myeloid leukemia (AML) in remission after intensive chemotherapy. The dosing schedule of oral-Aza (14 days/2
Externí odkaz:
https://doaj.org/article/1da3b8771381489588b67244fd735638
Autor:
Ibrahim Al Nabhani, Claire Andrews, Jad Sibai, Eshetu Atenafu, Taylor Young, Steven M. Chan, Vikas Gupta, Dawn Maze, Aaron D. Schimmer, Andre C. Schuh, Karen Yee, Hassan Sibai
Publikováno v:
eJHaem, Vol 4, Iss 1, Pp 232-235 (2023)
Abstract PEG‐asparaginase is used as a treatment for Philadelphia‐negative acute lymphoblastic leukemia. In pediatric studies, triglycerides (TGs) were affected more by PEG‐asparaginase than by native L‐asparaginase (10.0% vs. 5.5%). We condu
Externí odkaz:
https://doaj.org/article/e50e7e9e08b74513abd28ce4a7d9068c
Autor:
Idit Dotan, Jiaqi Yang, Jiro Ikeda, Ziv Roth, Evan Pollock-Tahiri, Harsh Desai, Tharini Sivasubramaniyam, Sonia Rehal, Josh Rapps, Yu Zhe Li, Helen Le, Gedaliah Farber, Edouard Alchami, Changting Xiao, Saraf Karim, Marcela Gronda, Michael F. Saikali, Amit Tirosh, Kay-Uwe Wagner, Jacques Genest, Aaron D. Schimmer, Vikas Gupta, Mark D. Minden, Carolyn L. Cummins, Gary F. Lewis, Clinton Robbins, Jenny Jongstra-Bilen, Myron Cybulsky, Minna Woo
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Loss of myeloid JAK2 promotes atherosclerosis in an ApoE knockout mouse model. This is associated with decreased cholesterol efflux from bone-marrow-derived macrophages.
Externí odkaz:
https://doaj.org/article/8f5bbf65f53546318be8781e62cd0a46
Autor:
Aaron D. Schimmer
Publikováno v:
Haematologica, Vol 107, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/bfe161181b6d44399c27739122cba9ec
Autor:
Camilla Zimmermann, Rinat Nissim, Sarah Hales, Carmine Malfitano, Anne Rydall, Gary Rodin, Sumit Gupta, Sarah Alexander, Kenneth Mah, Stephanie M Nanos, Katharina Schultebraucks, Lindsay A Jibb, Aaron D Schimmer, Charles Marmar
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction The diagnosis, progression or recurrence of cancer is often highly traumatic for family caregivers (FCs), but systematic assessments of distress and approaches for its prevention and treatment are lacking. Acute leukaemia (AL) is a life-
Externí odkaz:
https://doaj.org/article/371fe31d38804e4c9c4dbc28a70f9b9d
Autor:
Arvind Singh Mer, Emily M. Heath, Seyed Ali Madani Tonekaboni, Nergiz Dogan-Artun, Sisira Kadambat Nair, Alex Murison, Laura Garcia-Prat, Liran Shlush, Rose Hurren, Veronique Voisin, Gary D. Bader, Corey Nislow, Mattias Rantalainen, Soren Lehmann, Mark Gower, Cynthia J. Guidos, Mathieu Lupien, John E. Dick, Mark D. Minden, Aaron D. Schimmer, Benjamin Haibe-Kains
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Molecular heterogeneity of acute myeloid leukaemia (AML) across patients is a major challenge for prognosis and therapy. Here, the authors show that NPM1 mutated AML is a heterogeneous class, consisting of two subtypes which exhibit distinct molecula
Externí odkaz:
https://doaj.org/article/a1a1fb4ad66d4a54b1ec1c09785a2551
Autor:
Ruiqi Chen, Xing Liu, Arjun D. Law, Solaf Kanfar, Dawn Maze, Steven M. Chan, Vikas Gupta, Karen W. Yee, Mark D. Minden, Aaron D. Schimmer, Andre C. Schuh, Caroline J. McNamara, Tracy Murphy, Anna Xu, Umberto Falcone, Jack Seki, Hassan Sibai
Publikováno v:
Current Oncology, Vol 28, Iss 1, Pp 128-137 (2020)
Background: venous thromboembolism (VTE) is a well-known complication in adults with acute lymphoblastic leukemia (ALL), especially in patients treated with asparaginase (ASNase)-including regiments. However, VTE risk in adult Philadelphia-positive A
Externí odkaz:
https://doaj.org/article/52f8617b934048549a4137619b3d7db4
Autor:
Hannah N Kozlowski, Michael E Farkouh, Meredith S Irwin, Laszlo G Radvanyi, Aaron D Schimmer, Uri Tabori, Norman D Rosenblum
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp 1-4 (2020)
Abstract COVID‐19 has halted research around the globe and forced researchers out of their laboratories. Non‐emergency medical appointments were canceled. Ongoing clinical trials were challenged to create new modes of operation while public press
Externí odkaz:
https://doaj.org/article/562f1d8665274226afee97ac54c94821