Zobrazeno 1 - 10
of 412
pro vyhledávání: '"A D, Rowan"'
Autor:
Diane T. Brewster, Bruce L. Bycroft, Janine M. Cooney, Sarah B. Cordiner, Martin B. Hunt, Dwayne J. A. Jensen, Tony K. McGhie, Catherine E. Sansom, John W. van Klink, Daryl D. Rowan
Publikováno v:
ACS Chemical Health & Safety. 30:63-71
Publikováno v:
iScience, Vol 23, Iss 3, Pp - (2020)
Summary: Long-term care facilities are significant reservoirs of antimicrobial-resistant organisms, and patients with advanced dementia are particularly vulnerable to multidrug-resistant organism (MDRO) acquisition and antimicrobial overuse. In this
Externí odkaz:
https://doaj.org/article/74b966c1328141df8065183455d041cd
Publikováno v:
New Zealand Journal of Forestry Science, Vol 48, Iss 1, Pp 1-19 (2018)
Abstract Background Restoring erosion-prone land with indigenous species, whether by managed reforestation (planting) or by passive natural reversion, is reliant on knowing which species mix is likely to provide the quickest and most effective mitiga
Externí odkaz:
https://doaj.org/article/2ce57d6220494c3ab16d2916fad9a1bd
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The microbiome of freshwater fish has important implications for both commercial and recreational fishing because it can have significant impacts on host heath, spoilage rates, and susceptibility to disease. The aqueous environment serves as a possib
Externí odkaz:
https://doaj.org/article/d2d8699a25fd40f4944221d18374e83d
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 1, p e1006685 (2019)
Osteoarthritis (OA) is a degenerative condition caused by dysregulation of multiple molecular signalling pathways. Such dysregulation results in damage to cartilage, a smooth and protective tissue that enables low friction articulation of synovial jo
Externí odkaz:
https://doaj.org/article/1e922eac8794470196aaaa3edf65799a
Autor:
H. Boldingh, T. Pereira, S. Shepherd, K. Hewitt, J. Cooney, D. Rowan, D. Hedderley, D. Jensen, T. Trower, A. Richardson
Publikováno v:
Acta Horticulturae. :155-162
Autor:
Jonathan Baker, Adrian M D Falconer, David J Wilkinson, G Nicholas Europe-Finner, Gary J Litherland, Andrew D Rowan
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195864 (2018)
Many catabolic stimuli, including interleukin-1 (IL-1) in combination with oncostatin M (OSM), promote cartilage breakdown via the induction of collagen-degrading collagenases such as matrix metalloproteinase 1 (MMP1) and MMP13 in human articular cho
Externí odkaz:
https://doaj.org/article/dd7b44edb653406f81df8918086f1e74
Autor:
Christopher D Macdonald, Adrian M D Falconer, Chun Ming Chan, David J Wilkinson, Andrew Skelton, Louise Reynard, Gary J Litherland, G Nicholas Europe-Finner, Andrew D Rowan
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207240 (2018)
Irreversible cartilage collagen breakdown by the collagenolytic matrix metalloproteinases (MMPs)-1 and MMP-13 represents a key event in pathologies associated with tissue destruction such as arthritis. Inflammation is closely associated with such pat
Externí odkaz:
https://doaj.org/article/6794cdb9cbfc432f992af1601bd2260d
Autor:
David J. Wilkinson, Kathleen Cheung, Hua Lin, David Young, Ramsay Refaie, Maria del Carmen Arques, Sabina Janciauskiene, Andrew D. Rowan, Adrian M. D. Falconer, Helen L. Wright, Kazuhiro Yamamoto, Kenneth S. Rankin, Sarah Charlton
Publikováno v:
FEBS JOURNAL
Matrix metalloproteinase-13 (MMP-13) is a uniquely important collagenase that promotes the irreversible destruction of cartilage collagen in osteoarthritis (OA). Collagenase activation is a key control point for cartilage breakdown to occur, yet our
Publikováno v:
Microbial Cell, Vol 3, Iss 4, Pp 178-180 (2016)
The misuse of antibiotics has led to the development and spread of antibiotic resistance in clinically important pathogens. These resistant infections are having a significant impact on treatment outcomes and contribute to approximately 25,000 deaths
Externí odkaz:
https://doaj.org/article/04676a696e514af1beda3e6adeb959cd