Zobrazeno 1 - 10
of 219
pro vyhledávání: '"A D, Redd"'
Autor:
Adam Epstein-Shuman, Joanne H. Hunt, Patrizio Caturegli, Patrick Winguth, Reinaldo E. Fernandez, Gracie M. Rozek, Xianming Zhu, Nicholas A. DiRico, Armaan Jamal, Yu-Hsiang Hsieh, Yukari C. Manabe, Andrew D. Redd, Steven J. Reynolds, Annukka A.R. Antar, Oliver Laeyendecker
Publikováno v:
International Journal of Infectious Diseases, Vol 150, Iss , Pp 107289- (2025)
Introduction: Autoantibodies (AAbs) directed against interferon alpha (aIFNα), nuclear antigens (ANAs), anti-cardiolipin (aCL), and anti-beta 2 glycoprotein 1 (aβ2GP1), have been demonstrated to significantly correlate with the severity of acute Co
Externí odkaz:
https://doaj.org/article/594bfb9bc36e4a728a9fff60d9eadec5
Autor:
Minh Ha Ngo, Joshua Pankrac, Ryan C. Y. Ho, Emmanuel Ndashimye, Rahul Pawa, Renata Ceccacci, Tsigereda Biru, Abayomi S. Olabode, Katja Klein, Yue Li, Colin Kovacs, Robert Assad, Jeffrey M. Jacobson, David H. Canaday, Stephen Tomusange, Samiri Jamiru, Aggrey Anok, Taddeo Kityamuweesi, Paul Buule, Ronald M. Galiwango, Steven J. Reynolds, Thomas C. Quinn, Andrew D. Redd, Jessica L. Prodger, Jamie F. S. Mann, Eric J. Arts
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
To date, an affordable, effective treatment for an HIV-1 cure remains only a concept with most “latency reversal” agents (LRAs) lacking specificity for the latent HIV-1 reservoir and failing in early clinical trials. We assessed HIV-1 latency rev
Externí odkaz:
https://doaj.org/article/c4e48e2d64a24cd4aecbe0e0f13130b6
HIV-1 subtype A1, D, and recombinant proviral genome landscapes during long-term suppressive therapy
Autor:
Guinevere Q. Lee, Pragya Khadka, Sarah N. Gowanlock, Dennis C. Copertino, Maggie C. Duncan, F. Harrison Omondi, Natalie N. Kinloch, Jingo Kasule, Taddeo Kityamuweesi, Paul Buule, Samiri Jamiru, Stephen Tomusange, Aggrey Anok, Zhengming Chen, R. Brad Jones, Ronald M. Galiwango, Steven J. Reynolds, Thomas C. Quinn, Zabrina L. Brumme, Andrew D. Redd, Jessica L. Prodger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The primary obstacle to curing HIV-1 is a reservoir of CD4+ cells that contain stably integrated provirus. Previous studies characterizing the proviral landscape, which have been predominantly conducted in males in the United States and Euro
Externí odkaz:
https://doaj.org/article/8753461e8307400b835f50ad980f61a1
Autor:
Fatima Zaman, Melissa L. Smith, Ashwin Balagopal, Christine M. Durand, Andrew D. Redd, Aaron A. R. Tobian
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT The presence of the HIV-1 reservoir, a group of immune cells that contain intact, integrated, and replication-competent proviruses, is a major challenge to cure HIV-1. HIV-1 reservoir cells are largely unaffected by the cytopathic effects of
Externí odkaz:
https://doaj.org/article/77c80657813d46bbac0a1ffbd7ae670c
Autor:
Xianming Zhu, Eshan U. Patel, Stephen A. Berry, Mary K. Grabowski, Alison G. Abraham, Thibaut Davy-Mendez, Brenna Hogan, Keri N. Althoff, Andrew D. Redd, Oliver Laeyendecker, Thomas C. Quinn, Kelly A. Gebo, Aaron A.R. Tobian
Publikováno v:
EClinicalMedicine, Vol 73, Iss , Pp 102690- (2024)
Summary: Background: Thirty-day hospital readmission measures quality of care, but there are limited data among people with HIV (PWH) and people without HIV (PWoH) in the era of universal recommendation for antiretroviral therapy. We descriptively co
Externí odkaz:
https://doaj.org/article/49d5a0c4e4ee4028b48d057c6a0e5106
Autor:
Walker D. Redd, Chelsea Anderson, Anne F. Peery, Temitope O. Keku, John T. Woosley, Robert S. Sandler
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 3, Pp 336-343 (2024)
Background and Aims: Microscopic colitis (MC) is a common cause of chronic diarrhea; however, the clinical course of this disease is poorly understood. We aimed to investigate how patients diagnosed with MC were treated in routine clinical practice a
Externí odkaz:
https://doaj.org/article/e0dcc02792dc4b4fbcbdfb9cd537c41f
Autor:
Andrew P. Hederman, Harini Natarajan, Leo Heyndrickx, Kevin K. Ariën, Joshua A. Wiener, Peter F. Wright, Evan M. Bloch, Aaron A. R. Tobian, Andrew D. Redd, Joel N. Blankson, Amihai Rottenstreich, Gila Zarbiv, Dana Wolf, Tessa Goetghebuer, Arnaud Marchant, Margaret E. Ackerman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract SARS-CoV-2 variants have continuously emerged in the face of effective vaccines. Reduced neutralization against variants raises questions as to whether other antibody functions are similarly compromised, or if they might compensate for lost
Externí odkaz:
https://doaj.org/article/cee7a78f47b5458c87ac726e1a6998d6
Autor:
Roux-Cil Ferreira, Steven J. Reynolds, Adam A. Capoferri, Owen R. Baker, Erin E. Brown, Ethan Klock, Jernelle Miller, Jun Lai, Sharada Saraf, Charles Kirby, Briana Lynch, Jada Hackman, Sarah N. Gowanlock, Stephen Tomusange, Samiri Jamiru, Aggrey Anok, Taddeo Kityamuweesi, Paul Buule, Daniel Bruno, Craig Martens, Rebecca Rose, Susanna L. Lamers, Ronald M. Galiwango, Art F.Y. Poon, Thomas C. Quinn, Jessica L. Prodger, Andrew D. Redd
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105040- (2024)
Summary: Background: The principal barrier to an HIV cure is the presence of the latent viral reservoir (LVR), which has been understudied in African populations. From 2018 to 2019, Uganda instituted a nationwide rollout of ART consisting of Dolutegr
Externí odkaz:
https://doaj.org/article/7fa7f6eb718b411a877cdd47fd239934
Autor:
Brenderia A. Cameron, Angela Z. Xue, Akshatha Kiran, Sean LaFata, Adolfo A. Ocampo, Justin McCallen, Christopher J. Lee, Stephanie A. Borinsky, Walker D. Redd, Cary C. Cotton, Swathi Eluri, Craig C. Reed, Evan S. Dellon
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 5, Pp 612-614 (2024)
Externí odkaz:
https://doaj.org/article/67cc7cf4a27549f58245b330f6b53dd7
Autor:
Hannah Hussey, Helena Vreede, Mary-Ann Davies, Alexa Heekes, Emma Kalk, Diana Hardie, Gert van Zyl, Michelle Naidoo, Erna Morden, Jamy-Lee Bam, Nesbert Zinyakatira, Chad M Centner, Jean Maritz, Jessica Opie, Zivanai Chapanduka, Hassan Mahomed, Mariette Smith, Annibale Cois, David Pienaar, Andrew D Redd, Wolfgang Preiser, Robert Wilkinson, Andrew Boulle, Nei-Yuan Hsiao
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 8, p e0003554 (2024)
In low- and middle-income countries where SARS-CoV-2 testing is limited, seroprevalence studies can help describe and characterise the extent of the pandemic, as well as elucidate protection conferred by prior exposure. We conducted repeated cross-se
Externí odkaz:
https://doaj.org/article/873937e3de1e4f86b173ed46ab671d06