Zobrazeno 1 - 10
of 730
pro vyhledávání: '"A D, Paterson"'
Autor:
Henderikus E. Boersma, Andries J. Smit, Andrew D. Paterson, Bruce H. R. Wolffenbuttel, Melanie M. van der Klauw
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract We aimed to assess the association of SAF with cardiovascular mortality in the general population and the possible association between SAF with other disease-specific mortality rates. We evaluated 77,143 participants without known diabetes o
Externí odkaz:
https://doaj.org/article/9277188a07fe497885577f11697d8288
Autor:
R. D. M. Varkevisser, A. Cecil, C. Prehn, D. Mul, H. J. Aanstoot, A. D. Paterson, B. H. R. Wolffenbuttel, M. M. van der Klauw
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study investigates impaired awareness of hypoglycaemia (IAH), a complication of insulin therapy affecting 20–40% of individuals with type 1 diabetes. The exact pathophysiology is unclear, therefore we sought to identify metabolic sign
Externí odkaz:
https://doaj.org/article/fe07f1cc4d12473ab279f90bdd5b5bf4
Autor:
Alannah McEvoy, Caroul Chawar, Amel Lamri, Jacqueline Hudson, Luciano Minuzzi, David C. Marsh, Lehana Thabane, Andrew D. Paterson, Zainab Samaan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Opioid use disorder continues to be a health concern with a high rate of opioid related deaths occurring worldwide. Medication Assisted Treatments (MAT) have been shown to reduce opioid withdrawal, cravings and opioid use, however variabilit
Externí odkaz:
https://doaj.org/article/67ad56d376fb4475a75f2b513a7e85d6
Publikováno v:
PLoS Genetics, Vol 20, Iss 4, p e1011221 (2024)
Genetic effects can be sex-specific, particularly for traits such as testosterone, a sex hormone. While sex-stratified analysis provides easily interpretable sex-specific effect size estimates, the presence of sex-differences in SNP effect implies a
Externí odkaz:
https://doaj.org/article/6778911562f740649181b33d71f43468
Autor:
Sarah A. Gagliano Taliun, Ian R. Dinsmore, Tooraj Mirshahi, Alexander R. Chang, Andrew D. Paterson, Moumita Barua
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Our GWAS of hematuria in the UK Biobank identified 6 loci, some of which overlap with loci for albuminuria suggesting pleiotropy. Since clinical syndromes are often defined by combinations of traits, generating a combined phenotype can impro
Externí odkaz:
https://doaj.org/article/2961d97a0ea84df2982656a4fb202606
Autor:
Paul D. Paterson, MD, Matthew J. Kirsch, MD, Larry E. Miller, PhD, PStat, Demetrio J. Aguila, III, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 2, p e5647 (2024)
Background:. The duration of postoperative leave varies by the carpal tunnel release (CTR) technique. This study aimed to determine the time to return to work (RTW) after CTR with ultrasound (CTR-US) guidance and identify factors contributing to this
Externí odkaz:
https://doaj.org/article/1bd9ef2c94d342b19e7b969d10bc130b
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionBiological sex influences both overall adiposity and fat distribution. Further, testosterone and sex hormone binding globulin (SHBG) influence adiposity and metabolic function, with differential effects of testosterone in men and women. H
Externí odkaz:
https://doaj.org/article/c563aec5f0894cbb8a653b61251602db
Autor:
Charlotte E. Vollenbrock, Delnaz Roshandel, Melanie M. van der Klauw, Bruce H. R. Wolffenbuttel, Andrew D. Paterson
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Skin autofluorescence (SAF) is a non-invasive measure reflecting accumulation of advanced glycation endproducts (AGEs) in the skin. Higher SAF levels are associated with an increased risk of developing type 2 diabetes and cardiova
Externí odkaz:
https://doaj.org/article/846936a631ad44b391cebd661bde3dc3
Autor:
Sarah A. Gagliano Taliun, Ian R. Dinsmore, Tooraj Mirshahi, Alexander R. Chang, Andrew D. Paterson, Moumita Barua
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/47fbc4e88ff44fc7b1bf3fb2c70a986c
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Functional annotations have the potential to increase power of genome-wide association studies (GWAS) by prioritizing variants according to their biological function, but this potential has not been well studied. We comprehensively evaluated
Externí odkaz:
https://doaj.org/article/c95a8965bed84072a2b5f1642e9edf85