Zobrazeno 1 - 10 of 232 pro vyhledávání: '"A D, Klion"'
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Akademický článek
Challenging assumptions about the demographics of eosinophilic gastrointestinal diseases: A systematic review
Autor: Mirna Chehade, MD, MPH, Benjamin L. Wright, MD, Samantha Walsh, MLS, MA, Dominique D. Bailey, MD, Amanda B. Muir, MD, Amy D. Klion, MD, Margaret H. Collins, MD, Carla M. Davis, MD, Glenn T. Furuta, MD, Sandeep Gupta, MD, Paneez Khoury, MD, Kathryn A. Peterson, MD, Elizabeth T. Jensen, PhD
Publikováno v: Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 3, Pp 100260- (2024)
Background: The demographic characteristics of patients with eosinophilic gastrointestinal diseases (EGIDs) are poorly understood. Population-based assessments of EGID demographics may indicate health disparities in diagnosis. Objectives: We aimed to
Externí odkaz: https://doaj.org/article/1b5978b1272b4a1e8c778c55c02c4eb6
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2
Akademický článek
Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection
Autor: Andrea C. Bohrer, Ehydel Castro, Claire E. Tocheny, Maike Assmann, Benjamin Schwarz, Eric Bohrnsen, Michelle A. Makiya, Fanny Legrand, Kerry L. Hilligan, Paul J. Baker, Flor Torres-Juarez, Zhidong Hu, Hui Ma, Lin Wang, Liangfei Niu, Zilu Wen, Sang H. Lee, Olena Kamenyeva, Keith D. Kauffman, Michele Donato, Alan Sher, Daniel L. Barber, Laura E. Via, Thomas J. Scriba, Purvesh Khatri, Yanzheng Song, Ka-Wing Wong, Catharine M. Bosio, Amy D. Klion, Katrin D. Mayer-Barber
Publikováno v: Cell Reports, Vol 40, Iss 4, Pp 111144- (2022)
Summary: Influx of eosinophils into the lungs is typically associated with type II responses during allergy and fungal and parasitic infections. However, we previously reported that eosinophils accumulate in lung lesions during type I inflammatory re
Externí odkaz: https://doaj.org/article/4cc9d670630f4c0ab39dbfc2f415fe75
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4
Effect of Dupilumab on Blood Eosinophil Counts in Patients With Asthma, Chronic Rhinosinusitis With Nasal Polyps, Atopic Dermatitis, or Eosinophilic Esophagitis
Autor: Michael E, Wechsler, Amy D, Klion, Pierluigi, Paggiaro, Parameswaran, Nair, Delphine, Staumont-Salle, Amr, Radwan, Robert R, Johnson, Upender, Kapoor, Faisal A, Khokhar, Nadia, Daizadeh, Zhen, Chen, Elizabeth, Laws, Benjamin, Ortiz, Juby A, Jacob-Nara, Leda P, Mannent, Paul J, Rowe, Yamo, Deniz
Publikováno v: The Journal of Allergy and Clinical Immunology: In Practice. 10:2695-2709
Transient increases in blood eosinophil counts have been observed in dupilumab clinical trials.To assess eosinophil counts and eosinophilia-related treatment-emergent adverse events (TEAEs) across 11 dupilumab clinical trials, comparing adult and ado
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d17ae24f7c3ae72d37755ec2db5ff76
https://doi.org/10.1016/j.jaip.2022.05.019
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5
Clinical exome sequencing of 1000 families with complex immune phenotypes: Toward comprehensive genomic evaluations
Autor: Morgan N. Similuk, Jia Yan, Rajarshi Ghosh, Andrew J. Oler, Luis M. Franco, Michael R. Setzer, Michael Kamen, Colleen Jodarski, Thomas DiMaggio, Joie Davis, Rachel Gore, Leila Jamal, Adrienne Borges, Nicole Gentile, Julie Niemela, Chenery Lowe, Kathleen Jevtich, Yunting Yu, Haley Hullfish, Amy P. Hsu, Celine Hong, Patricia Littel, Bryce A. Seifert, Joshua Milner, Jennifer J. Johnston, Xi Cheng, Zhiwen Li, Daniel Veltri, Ke Huang, Krishnaveni Kaladi, Jason Barnett, Lingwen Zhang, Nikita Vlasenko, Yongjie Fan, Eric Karlins, Satishkumar Ranganathan Ganakammal, Robert Gilmore, Emily Tran, Alvin Yun, Joseph Mackey, Svetlana Yazhuk, Justin Lack, Vasudev Kuram, Wenjia Cao, Susan Huse, Karen Frank, Gary Fahle, Sergio Rosenzweig, Yan Su, SuJin Hwang, Weimin Bi, John Bennett, Ian A. Myles, Suk See De Ravin, Ivan Fuss, Warren Strober, Bibiana Bielekova, Adriana Almeida de Jesus, Raphaela Goldbach-Mansky, Peter Williamson, Kelly Kumar, Caeden Dempsy, Pamela Frischmeyer-Guerrerio, Robin Fisch, Hyejeong Bolan, Dean D. Metcalfe, Hirsh Komarow, Melody Carter, Kirk M. Druey, Irini Sereti, Lesia Dropulic, Amy D. Klion, Paneez Khoury, Elise M. O' Connell, Nicole C. Holland-Thomas, Thomas Brown, David H. McDermott, Philip M. Murphy, Vanessa Bundy, Michael D. Keller, Christine Peng, Helen Kim, Stephanie Norman, Ottavia M. Delmonte, Elizabeth Kang, Helen C. Su, Harry Malech, Alexandra Freeman, Christa Zerbe, Gulbu Uzel, Jenna R.E. Bergerson, V. Koneti Rao, Kenneth N. Olivier, Jonathan J. Lyons, Andrea Lisco, Jeffrey I. Cohen, Michail S. Lionakis, Leslie G. Biesecker, Sandhya Xirasagar, Luigi D. Notarangelo, Steven M. Holland, Magdalena A. Walkiewicz
Publikováno v: J Allergy Clin Immunol
BACKGROUND: Prospective genetic evaluation of patients at our referral research hospital presents clinical research challenges. OBJECTIVE: This study sought not only a single-gene explanation for participants’ immune-related presentations, but view
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f8a28d08c3a4960c10b7fc3d195a47
https://doi.org/10.1016/j.jaci.2022.06.009
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7
Comparison of Different Sampling Methods to Catch Lymphatic Filariasis Vectors in a Sudan Savannah Area of Mali
Autor: Yaya Ibrahim Coulibaly, Moussa Sangare, Housseini Dolo, Salif Seriba Doumbia, Siaka Yamoussa Coulibaly, Ilo Dicko, Abdoul Fatao Diabate, Michel Emmanuel Coulibaly, Lamine Soumaoro, Abdallah Amadou Diallo, Massitan Dembele, Sekou Fantamady Traore, Michelle Stanton, Benjamin Guibehi Koudou, Amy D. Klion, Thomas B. Nutman, Louise Kelly-Hope, Moses John Bockarie
Publikováno v: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
Am J Trop Med Hyg
There is a need for better tools to monitor the transmission of lymphatic filariasis and malaria in areas undergoing interventions to interrupt transmission. Therefore, mosquito collection methods other than human landing catch (HLC) are needed. This
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c0c040e8970ed044d8d16c37a3d4c7
https://doi.org/10.4269/ajtmh.21-0667
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9
Approach to the patient with suspected hypereosinophilic syndrome
Autor: Amy D. Klion
Publikováno v: Hematology Am Soc Hematol Educ Program
Hypereosinophilic syndromes (HES) are a heterogenous group of rare disorders with clinical manifestations ranging from fatigue to life-threatening endomyocardial fibrosis and thromboembolic events. Given the broad differential diagnosis of HES, a com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266e5208d1a017f0f0b40bc89ead578b
https://europepmc.org/articles/PMC9821533/
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10
Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial
Autor: Amy D. Klion, Florence Roufosse, Marc E. Rothenberg, Suyong Yun Kirby, Jane H Bentley, Jonathan Steinfeld, Martyn J. Gilson, Eric S. Bradford, Steven W. Yancey, Andrew J. Wardlaw, Jean-Emmanuel Kahn, Gerald J. Gleich
Publikováno v: Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, Elsevier, 2020, 146 (6), pp.1397-1405. ⟨10.1016/j.jaci.2020.08.037⟩
Journal of allergy and clinical immunology
Background: Anti–IL-5 therapy is a potential treatment for patients with hypereosinophilic syndrome (HES), although its clinical efficacy is unclear. Objective: We sought to investigate the clinical efficacy and safety of mepolizumab versus placebo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918d53754a16796502660c4683784f2a
https://doi.org/10.1016/j.jaci.2020.08.037
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