Zobrazeno 1 - 10
of 834
pro vyhledávání: '"A D, Johansen"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/1872d5632c924969a441c18964dd823b
Autor:
Tomalika R. Ullah, Matt D. Johansen, Katherine R. Balka, Rebecca L. Ambrose, Linden J. Gearing, James Roest, Julian P. Vivian, Sunil Sapkota, W. Samantha N. Jayasekara, Daniel S. Wenholz, Vina R. Aldilla, Jun Zeng, Stefan Miemczyk, Duc H. Nguyen, Nicole G. Hansbro, Rajan Venkatraman, Jung Hee Kang, Ee Shan Pang, Belinda J. Thomas, Arwaf S. Alharbi, Refaya Rezwan, Meredith O’Keeffe, William A. Donald, Julia I. Ellyard, Wilson Wong, Naresh Kumar, Benjamin T. Kile, Carola G. Vinuesa, Graham E. Kelly, Olivier F. Laczka, Philip M. Hansbro, Dominic De Nardo, Michael P. Gantier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract TANK-binding kinase 1 (TBK1) is a key signalling component in the production of type-I interferons, which have essential antiviral activities, including against SARS-CoV-2. TBK1, and its homologue IκB kinase-ε (IKKε), can also induce pro-
Externí odkaz:
https://doaj.org/article/780fdb67fa074e35823aa88357231e9d
Autor:
Tristram A. J. Ryan, Alexander Hooftman, Aisling M. Rehill, Matt D. Johansen, Eóin C. O’ Brien, Juliana E. Toller-Kawahisa, Mieszko M. Wilk, Emily A. Day, Hauke J. Weiss, Pourya Sarvari, Emilio G. Vozza, Fabian Schramm, Christian G. Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G. Hansbro, Gavin McManus, Laura O’Doherty, Siobhan Gargan, Aideen Long, Jean Dunne, Clíona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G. Fallon, Kingston H. G. Mills, Emma M. Creagh, James S. O’ Donnell, Paul J. Hertzog, Philip M. Hansbro, Rachel M. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Zbigniew Zasłona, Luke A. J. O’Neill
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Excessive inflammation-associated coagulation is a feature of infectious diseases, occurring in such conditions as bacterial sepsis and COVID-19. It can lead to disseminated intravascular coagulation, one of the leading causes of mortality w
Externí odkaz:
https://doaj.org/article/0df3d79819534a4786cd65226889c413
Autor:
Gaetano Scaramuzzo, Francesco Nucera, Alessio Asmundo, Roberto Messina, Matilde Mari, Federica Montanaro, Matt D. Johansen, Francesco Monaco, Guido Fadda, Giovanni Tuccari, Nicole G. Hansbro, Philip M. Hansbro, Trevor T. Hansel, Ian M. Adcock, Antonio David, Paul Kirkham, Gaetano Caramori, Carlo Alberto Volta, Savino Spadaro
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-24 (2023)
Abstract The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can be asymptomatic or cause a disease (COVID-19) characterized by different levels of severity. The main cause of severe COVID-19 and death is represented by acute (
Externí odkaz:
https://doaj.org/article/09db15bec1ab49ba975346d548e55894
Autor:
Romain Rouet, Jake Y. Henry, Matt D. Johansen, Meghna Sobti, Harikrishnan Balachandran, David B. Langley, Gregory J. Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L. Burnett, Simon H. J. Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J. Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C. Goodnow, Stuart G. Turville, William D. Rawlinson, Rowena A. Bull, Alastair G. Stewart, Philip M. Hansbro, Daniel Christ
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Here, Rouet et al. present a strategy for the identification of broadly neutralising antibodies against SARS-CoV-2 receptor binding domain from peripheral blood mononuclear cells of convalescent patients, which enabled the identification of a new cla
Externí odkaz:
https://doaj.org/article/d7c35bcc59bc4a9fb845343c96f9aa30
Autor:
Anneliese S. Ashhurst, Matt D. Johansen, Joshua W. C. Maxwell, Skye Stockdale, Caroline L. Ashley, Anupriya Aggarwal, Rezwan Siddiquee, Stefan Miemczyk, Duc H. Nguyen, Joel P. Mackay, Claudio Counoupas, Scott N. Byrne, Stuart Turville, Megan Steain, James A. Triccas, Philip M. Hansbro, Richard J. Payne, Warwick J. Britton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Current vaccines against SARS-CoV-2 reduce mortality but are less effective in preventing infection. Here the authors show that intranasal vaccination with a subunit vaccine including an TLR2-stimulating adjuvant induces strong neutralising antibody
Externí odkaz:
https://doaj.org/article/f49a73582fab4d0ca1138c1978b8a154
Publikováno v:
Mobile DNA, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Mobile group I introns encode homing endonucleases that confer intron mobility initiated by a double-strand break in the intron-lacking allele at the site of insertion. Nuclear ribosomal DNA of some fungi and protists contain mobi
Externí odkaz:
https://doaj.org/article/87bd7cf93d3c45e2b8ec62bdaa2aa6e5
Autor:
Ilaria Salvato, Luca Ricciardi, Jessica Dal Col, Annunziata Nigro, Giorgio Giurato, Domenico Memoli, Assunta Sellitto, Erwin Pavel Lamparelli, Maria Assunta Crescenzi, Monica Vitale, Alessandro Vatrella, Francesco Nucera, Paola Brun, Federico Caicci, Paola Dama, Thomas Stiff, Leandro Castellano, Sobia Idrees, Matt D. Johansen, Alen Faiz, Peter A. Wark, Philip M. Hansbro, Ian M. Adcock, Gaetano Caramori, Cristiana Stellato
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe RNA-binding protein AU-rich-element factor-1 (AUF-1) participates to posttranscriptional regulation of genes involved in inflammation and cellular senescence, two pathogenic mechanisms of chronic obstructive pulmonary disease (COPD).
Externí odkaz:
https://doaj.org/article/fe7d7b5136784084a80901875472e5fb
Autor:
Julia Y. Kam, Elinor Hortle, Elizabeth Krogman, Sherridan E. Warner, Kathryn Wright, Kaiming Luo, Tina Cheng, Pradeep Manuneedhi Cholan, Kazu Kikuchi, James A. Triccas, Warwick J. Britton, Matt D. Johansen, Laurent Kremer, Stefan H. Oehlers
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The pathogen Mycobacterium abscessus can switch from a smooth colony form (S) into a highly inflammatory, rough colony form (R) during infection. Here, Kam et al. use an adult zebrafish model of M. abscessus chronic infection to illustrate difference
Externí odkaz:
https://doaj.org/article/21538f5988d2474e8bf1b3bb89145259
Autor:
Josephine Grandt, Anne‐Sofie H. Jensen, Mikkel P. Werge, Elias B. Rashu, Andreas Møller, Anders E. Junker, Lise Hobolth, Christian Mortensen, Christian D. Johansen, Mogens Vyberg, Reza Rafiolsadat Serizawa, Søren Møller, Lise Lotte Gluud, Nicolai J. Wewer Albrechtsen
Publikováno v:
Physiological Reports, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract Fatty liver disease has mainly been characterized under fasting conditions. However, as the liver is essential for postprandial homeostasis, identifying postprandial disturbances may be important. Here, we investigated postprandial changes i
Externí odkaz:
https://doaj.org/article/5b92858c4b1641adbc65716474f5fd74