Zobrazeno 1 - 10
of 8 506
pro vyhledávání: '"A D, Cohen"'
Autor:
Xuemei Zeng, Tara K. Lafferty, Anuradha Sehrawat, Yijun Chen, Pamela C. L. Ferreira, Bruna Bellaver, Guilherme Povala, M. Ilyas Kamboh, William E. Klunk, Ann D. Cohen, Oscar L. Lopez, Milos D. Ikonomovic, Tharick A. Pascoal, Mary Ganguli, Victor L. Villemagne, Beth E. Snitz, Thomas K. Karikari
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract Background Blood-based biomarkers are gaining grounds for the detection of Alzheimer’s disease (AD) and related disorders (ADRDs). However, two key obstacles remain: the lack of methods for multi-analyte assessments and the need for biomar
Externí odkaz:
https://doaj.org/article/c51e1a14802e4f3799358b5410df0e5b
Autor:
Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Determining the genetic architecture of Alzheimer’s disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron
Externí odkaz:
https://doaj.org/article/534dba93d5bf4620975ce9a0f564baf7
Autor:
Eric Van Buren, David Azzara, Javier Rangel-Moreno, Maria de la Luz Garcia-Hernandez, Shawn P. Murphy, Ethan D. Cohen, Ethan Lewis, Xihong Lin, Hae-Ryung Park
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The placenta is crucial for fetal development, yet the impact of environmental stressors such as arsenic exposure remains poorly understood. We apply single-cell RNA sequencing to analyze the response of the mouse placenta to arsenic, reveal
Externí odkaz:
https://doaj.org/article/976a33d3c545448d856969930799dfbf
Autor:
Laura Xicota, Lam-Ha T. Dang, Alice Lee, Sharon Krinsky-McHale, Deborah Pang, Lisa Melilli, Sid O'Bryant, Rachel L. Henson, Charles Laymon, Florence Lai, H. Diana Rosas, Beau Ances, Ira Lott, Christy Hom, Bradley Christian, Sigan Hartley, Shahid Zaman, Elizabeth Head, Mark Mapstone, Zhezhen Jin, Wayne Silverman, Nicole Schupf, Benjamin Handen, Joseph H. Lee, Howard J. Aizenstein, Beau M. Ances, Howard F. Andrews, Karen Bell, Rasmus Birn, Adam M. Brickman, Peter Bulova, Amrita Cheema, Kewei Chen, Bradley T. Christian, Isabel Clare, Lorraine Clark, Ann D. Cohen, John N. Constantino, Eric W. Doran, Anne Fagan, Eleanor Feingold, Tatiana M. Foroud, Benjamin L. Handen, Jordan Harp, Sigan L. Hartley, Rachel Henson, Lawrence Honig, Milos D. Ikonomovic, Sterling C. Johnson, Courtney Jordan, M.Ilyas Kamboh, David Keator, William E. Klunk, Julia K. Kofler, William Charles Kreisl, Sharon J. Krinsky-McHale, Patrick Lao, Ira T. Lott, Victoria Lupson, Chester A. Mathis, Davneet Singh Minhas, Neelesh Nadkarni, Sid O’Bryant, Melisa Parisi, Melissa Pettersen, Julie C. Price, Margaret Pulsifer, Michael S. Rafii, Eric Reiman, Batool Rizvi, Laurie Ryan, Frederick Schmitt, Wayne P. Silverman, Dana L. Tudorascu, Rameshwari Tumuluru, Benjamin Tycko, Badri Varadarajan, Desiree A. White, Michael A. Yassa, Fan Zhang
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105433- (2024)
Summary: Background: Individuals with Down syndrome (DS) are at high risk of early-onset Alzheimer's disease (AD); yet, some 20 percent do not develop any signs of dementia until after 65 years or in their lifetime. Mosaicism could contribute to this
Externí odkaz:
https://doaj.org/article/7bcbc45f9a5e40b7ab0502504ef1c084
Autor:
N. Mendes, L. Woestland, V. Drouineaud, F. Poirier, C. Lagrange, O. Rosenblum, J.-P. Wolf, C. Patrat, J. Brunelle, F. Pommier, D. Cohen, A. Condat
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e40501- (2024)
Assisted reproductive technologies have offered new ways and pathways to conceive a child. However, very few is known about insights into the complexities and challenges faced by trans fathers in contemporary parenthood journeys. This qualitative stu
Externí odkaz:
https://doaj.org/article/b19834382e024433b47346124bcb0d8d
Publikováno v:
Crime Science, Vol 13, Iss 1, Pp 1-16 (2024)
Abstract Transshipment is one of the most common activities occurring between carriers and fishing vessels to exchange fish, as well as fuel, crew, and gear at sea or at port. While transshipment reduces the need for the fishing vessels to visit port
Externí odkaz:
https://doaj.org/article/fce37f58c15d426294d0b14ec4f3884a
Autor:
Xuemei Zeng, Yijun Chen, Anuradha Sehrawat, Jihui Lee, Tara K. Lafferty, Julia Kofler, Sarah B. Berman, Robert A. Sweet, Dana L. Tudorascu, William E. Klunk, Milos D. Ikonomovic, Anna Pfister, Henrik Zetterberg, Beth E. Snitz, Anne D. Cohen, Victor L. Villemagne, Tharick A. Pascoal, M. llyas Kamboh, Oscar I. Lopez, Kaj Blennow, Thomas K. Karikari
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-22 (2024)
Abstract Alzheimer’s disease (AD), the most common form of dementia, remains challenging to understand and treat despite decades of research and clinical investigation. This might be partly due to a lack of widely available and cost-effective modal
Externí odkaz:
https://doaj.org/article/64c9dbe829a54f7ea0148397b7f5ae86
Autor:
C. M. Whitfield-Cargile, H. C. Chung, M. C. Coleman, N. D. Cohen, A. M. Chamoun-Emanuelli, I. Ivanov, J. S. Goldsby, L. A. Davidson, I. Gaynanova, Y. Ni, R. S. Chapkin
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-20 (2024)
Abstract Background The equine gastrointestinal (GI) microbiome has been described in the context of various diseases. The observed changes, however, have not been linked to host function and therefore it remains unclear how specific changes in the m
Externí odkaz:
https://doaj.org/article/6f6f60f13fc94f4db39c4ef87a7f2873
Publikováno v:
Horticulture Advances, Vol 2, Iss 1, Pp 1-25 (2024)
Abstract The first reports that auxins promoted root formation in cuttings and that indole-3-butyric acid (IBA) was a particularly effective treatment date from the early 1930s. Since its introduction into horticultural practice, the focus on improve
Externí odkaz:
https://doaj.org/article/8be75543da46444eaab119cb627d89bf
Autor:
Julie Ritter, João de Bragança, Carmen Auste, Alejandra Mendez, Phillip D. Cohen, Andrés Felipe Fajardo, Patrícia Loggetto, Karla Emília de Sá Rodrigues, Beverley M. Essue, Felicia M. Knaul, Sara M. Malone, Troy Quast, Russell S. Kirby, Eva Steliarova-Foucher, I-Chan Huang, Filip Meheus, Nickhill Bhakta
Publikováno v:
JCO Global Oncology, Vol , Iss 10 (2024)
PURPOSEAlthough financial hardship in childhood cancer contributes to poor outcomes, no standardized tool to assess its impact exists. Existing methods are heterogeneous and designed using high-income country (HIC), adult perspectives. This project a
Externí odkaz:
https://doaj.org/article/69d075b33c1b4471a34cd84d3ab77e7a