Zobrazeno 1 - 10
of 842
pro vyhledávání: '"A D, Bins"'
Autor:
Hilin Yildirim, Christiaan V Widdershoven, Maureen JB Aarts, Axel Bex, Haiko J Bloemendal, Deirdre M Bochove-Overgaauw, Paul Hamberg, Karin H Herbschleb, Tom van der Hulle, Brunolf W Lagerveld, Martijn GH van Oijen, Sjoukje F Oosting, Johannes V van Thienen, Astrid AM van der Veldt, Hans M Westgeest, Evelijn E Zeijdner, Katja KH Aben, Corina van den Hurk, Patricia J Zondervan, Adriaan D Bins
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Ongoing research in the field of both localized, locally advanced and metastatic renal cell carcinoma has resulted in the availability of multiple treatment options. Hence, many questions are still unanswered and await further res
Externí odkaz:
https://doaj.org/article/7899867013894664a81995245ef9db90
Autor:
Birgit S. Geurts, Thomas W. Battaglia, J. Maxime van Berge Henegouwen, Laurien J. Zeverijn, Gijs F. de Wit, Louisa R. Hoes, Hanneke van der Wijngaart, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Frans L. Opdam, Maja J. A. de Jonge, Geert A. Cirkel, Mariette Labots, Ann Hoeben, Emile D. Kerver, Adriaan D. Bins, Frans G.L. Erdkamp, Johan M. van Rooijen, Danny Houtsma, Mathijs P. Hendriks, Jan-Willem B. de Groot, Henk M. W. Verheul, Hans Gelderblom, Emile E. Voest
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background In this study we aimed to evaluate the efficacy and safety of the PD-L1 inhibitor durvalumab across various mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) tumours in the Drug Rediscovery Protocol (DRUP
Externí odkaz:
https://doaj.org/article/0e6af27c660548eab8d0d86d81fe251d
Autor:
Ben-Max de Ruiter, Maaike W. van de Kamp, Jonah P.Z. van Steenbergen, Martine Franckena, Joost L. Boormans, Jeantine M. de Feijter, Adriaan D. Bins, Maarten C.C.M. Hulshof, Theo M. de Reijke, Eva Schaake, Jorg R. Oddens
Publikováno v:
European Urology Open Science, Vol 39, Iss , Pp 7-13 (2022)
Background: Concurrent chemoradiotherapy (CRT) as a definitive treatment option for patients with nonmetastatic muscle-invasive bladder carcinoma (MIBC) is increasingly being applied in clinical practice. Objective: To assess the oncological and toxi
Externí odkaz:
https://doaj.org/article/e0a549a6bfef4220b4eb6863be5da434
Autor:
Michelle J. Klouwens, Jos J. A. Trentelman, Alex Wagemakers, Jasmin I. Ersoz, Adriaan D. Bins, Joppe W. Hovius
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionBorrelia burgdorferi sensu lato (sl) is the causative agent of Lyme borreliosis. Currently there is no human vaccine against Lyme borreliosis, and most research focuses on recombinant protein vaccines. DNA tattoo vaccination with B. afzel
Externí odkaz:
https://doaj.org/article/9fbcb23f85cf40fbb5847590c4f2e4ac
Autor:
Ide T Spaanderman, Fleur S Peters, Aldo Jongejan, Egbert J W Redeker, Cornelis J A Punt, Adriaan D Bins
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0251630 (2021)
Approximately 15% of Colon Cancers are Microsatellite Instable (MSI). Frameshift Peptides (FPs) formed in MSI Colon Cancer are potential targets for immunotherapeutic strategies. Here we comprehensively characterize the mutational landscape of 71 MSI
Externí odkaz:
https://doaj.org/article/e6c081e7b941478cbccd90efecb713e0
Autor:
M. Opdam, V. van der Noort, M. Kleijn, A. Glas, I. Mandjes, S. Kleiterp, F. S. Hilbers, D. T. Kruger, A. D. Bins, P. C. de Jong, P. P. J. B. M. Schiphorst, T. van Dalen, B. Flameling, R. C. Rietbroek, A. Beeker, S. M. van den Heiligenberg, S. D. Bakker, A. N. M. Wymenga, I. M. Oving, R. M. Bijlsma, P. J. van Diest, J. B. Vermorken, H. van Tinteren, S. C. Linn
Publikováno v:
Breast cancer research and treatment, 194(2), 265-278. Springer New York
Breast cancer research and treatment
Breast Cancer Research and Treatment, 194(2), 265-278. Springer New York
Opdam, M, van der Noort, V, Kleijn, M, Glas, A, Mandjes, I, Kleiterp, S, Hilbers, F S, Kruger, D T, Bins, A D, de Jong, P C, Schiphorst, P P J B M, van Dalen, T, Flameling, B, Rietbroek, R C, Beeker, A, van den Heiligenberg, S M, Bakker, S D, Wymenga, A N M, Oving, I M, Bijlsma, R M, van Diest, P J, Vermorken, J B, van Tinteren, H & Linn, S C 2022, ' Limiting systemic endocrine overtreatment in postmenopausal breast cancer patients with an ultralow classification of the 70-gene signature ', Breast Cancer Research and Treatment, vol. 194, no. 2, pp. 265-278 . https://doi.org/10.1007/s10549-022-06618-z
Breast cancer research and treatment
Breast Cancer Research and Treatment, 194(2), 265-278. Springer New York
Opdam, M, van der Noort, V, Kleijn, M, Glas, A, Mandjes, I, Kleiterp, S, Hilbers, F S, Kruger, D T, Bins, A D, de Jong, P C, Schiphorst, P P J B M, van Dalen, T, Flameling, B, Rietbroek, R C, Beeker, A, van den Heiligenberg, S M, Bakker, S D, Wymenga, A N M, Oving, I M, Bijlsma, R M, van Diest, P J, Vermorken, J B, van Tinteren, H & Linn, S C 2022, ' Limiting systemic endocrine overtreatment in postmenopausal breast cancer patients with an ultralow classification of the 70-gene signature ', Breast Cancer Research and Treatment, vol. 194, no. 2, pp. 265-278 . https://doi.org/10.1007/s10549-022-06618-z
Purpose Guidelines recommend endocrine treatment for estrogen receptor-positive (ER+) breast cancers for up to 10 years. Earlier data suggest that the 70-gene signature (MammaPrint) has potential to select patients that have an excellent survival wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff14e4330cdee35c7a55ca1f5f2e824
https://doi.org/10.1007/s10549-022-06618-z
https://doi.org/10.1007/s10549-022-06618-z
Autor:
Adriaan D. Bins, Jannie Borst, Matthew F. Krummel, Tomasz Ahrends, Victoria Iglesias-Guimarais, Evert de Vries, Astrid Bovens, Nikolina Bąbała
Supplemental Figures and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8441bb37cb3a9d86c9c8d84650ead2c2
https://doi.org/10.1158/2326-6066.22539103.v1
https://doi.org/10.1158/2326-6066.22539103.v1
Autor:
Adriaan D. Bins, Jannie Borst, Matthew F. Krummel, Tomasz Ahrends, Victoria Iglesias-Guimarais, Evert de Vries, Astrid Bovens, Nikolina Bąbała
In a mouse model of therapeutic DNA vaccination, we studied how the subcellular localization of vaccine protein impacts antigen delivery to professional antigen-presenting cells and efficiency of CTL priming. Cytosolic, membrane-bound, nuclear, and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3229bbf1d233535cfbc09a33779be63
https://doi.org/10.1158/2326-6066.c.6548992.v1
https://doi.org/10.1158/2326-6066.c.6548992.v1
Supplementary Figure Legends 1-2 from Skewing the T-Cell Repertoire by Combined DNA Vaccination, Host Conditioning, and Adoptive Transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75cdc61fd057f968d4bf6b3c591c2bc
https://doi.org/10.1158/0008-5472.22375337
https://doi.org/10.1158/0008-5472.22375337
Supplementary Figure 1 from Skewing the T-Cell Repertoire by Combined DNA Vaccination, Host Conditioning, and Adoptive Transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71769d2b4718e8c334651ea70bfeca6a
https://doi.org/10.1158/0008-5472.22375343.v1
https://doi.org/10.1158/0008-5472.22375343.v1