Zobrazeno 1 - 10
of 14
pro vyhledávání: '"A C, van der Graaf"'
Autor:
Daniël H. Swart, Martin de Haan, Jasper Stevens, Rob H. Henning, Sovan Adel, Adrianus C. van der Graaf, Nadir Ulu, Daan J. Touw, Guido Krenning
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 345-355 (2024)
Noncommunicable Chronic Diseases (NCD) are a socioeconomic burden and considered one of the major health challenges for coming decades. Mitochondrial dysfunction has been implicated mechanistically in their pathophysiology. Therefore, targeting mitoc
Externí odkaz:
https://doaj.org/article/b8f0e0d668de4738b59950a932a68715
Publikováno v:
Geoscientific Model Development, Vol 13, Pp 2451-2474 (2020)
The nitrogen cycle has been continuously disrupted by human activity over the past century, resulting in almost a tripling of the total reactive nitrogen fixation in Europe. Consequently, excessive amounts of reactive nitrogen (Nr) have manifested in
Externí odkaz:
https://doaj.org/article/e911831da0814695894899c416506167
Publikováno v:
Atmospheric Chemistry and Physics, Vol 18, Pp 13173-13196 (2018)
Atmospheric levels of reactive nitrogen have increased substantially during the last century resulting in increased nitrogen deposition to ecosystems, causing harmful effects such as soil acidification, reduction in plant biodiversity and eutrophi
Externí odkaz:
https://doaj.org/article/44dc5fbecdcb41f1a68ef47096601fdb
Autor:
S Tkáčiková, Guido Krenning, P. Vogelaar, Daniël Henri Swart, Robert H. Henning, Ľ Tkáčiková, D Nakladal, A C van der Graaf
Publikováno v:
European Journal of Pharmaceutical Sciences, 168:106033. ELSEVIER SCIENCE BV
Acute kidney injury (AKI) is a global healthcare burden attributable to high mortality and staggering costs of dialysis. The underlying causes of AKI include hypothermia and rewarming (H/R), ischemia/reperfusion (I/R), mitochondrial dysfunction and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce56ab2743fba0bf8abf3e834819803
https://doi.org/10.1016/j.ejps.2021.106033
https://doi.org/10.1016/j.ejps.2021.106033
Autor:
Fatemeh Talaei, Hjalmar R Bouma, Adrianus C Van der Graaf, Arjen M Strijkstra, Martina Schmidt, Robert H Henning
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22568 (2011)
Biogenic amines have been demonstrated to protect cells from apoptotic cell death. Herein we show for the first time that serotonin and dopamine increase H(2)S production by the endogenous enzyme cystathionine-β-synthase (CBS) and protect cells agai
Externí odkaz:
https://doaj.org/article/cbbbd15bb6a74579bfe9c147d7bbb5e7
Autor:
D, Nakladal, H, Buikema, A Reyes, Romero, S P H, Lambooy, J, Bouma, G, Krenning, P, Vogelaar, A C, van der Graaf, M R, Groves, J, Kyselovic, R H, Henning, L E, Deelman
Publikováno v:
Scientific Reports
SUL-compounds are protectants from cold-induced ischemia and mitochondrial dysfunction. We discovered that adding SUL-121 to renal grafts during warm machine reperfusion elicits a rapid improvement in perfusion parameters. Therefore, we investigate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4ad91331e1a675f4dee81d697e8f39c
https://pubmed.ncbi.nlm.nih.gov/30626882
https://pubmed.ncbi.nlm.nih.gov/30626882
Autor:
Marcel H. J. Ruiters, S. Korn, A. C. van der Graaf, C. M. Habraken, Arjen H. Petersen, N. van Ieperen, Laura Hesse, B. Goedewaagen, Martijn C. Nawijn, T. Smilda
Publikováno v:
Allergy, 73(4), 862-874. Wiley-Blackwell
Allergy
Allergy
BackgroundAllergen-specific immunotherapy can induce long-term suppression of allergic symptoms, reduce medication use, and prevent exacerbations of allergic rhinitis and asthma. Current treatment is based on crude allergen extracts, which contain im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd7b20f6766b25dd016f65931ffe4a2
https://research.rug.nl/en/publications/bb814cd4-dcd4-4e1d-8fdc-dc78867a84b5
https://research.rug.nl/en/publications/bb814cd4-dcd4-4e1d-8fdc-dc78867a84b5
