Zobrazeno 1 - 10
of 647
pro vyhledávání: '"A C, Wren"'
Autor:
Bilal Khalil, Deepak Chhangani, Melissa C. Wren, Courtney L. Smith, Jannifer H. Lee, Xingli Li, Christian Puttinger, Chih-Wei Tsai, Gael Fortin, Dmytro Morderer, Junli Gao, Feilin Liu, Chun Kim Lim, Jingjiao Chen, Ching-Chieh Chou, Cara L. Croft, Amanda M. Gleixner, Christopher J. Donnelly, Todd E. Golde, Leonard Petrucelli, Björn Oskarsson, Dennis W. Dickson, Ke Zhang, James Shorter, Shige H. Yoshimura, Sami J. Barmada, Diego E. Rincon-Limas, Wilfried Rossoll
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-27 (2022)
Abstract Background Cytoplasmic mislocalization and aggregation of TAR DNA-binding protein-43 (TDP-43) is a hallmark of the amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) disease spectrum, causing both nuclear loss-of-function an
Externí odkaz:
https://doaj.org/article/bbd064334e3c44abbee70cb5d84f3100
Autor:
Alexis Moscoso, Melissa C. Wren, Tammaryn Lashley, Erik Arstad, Melissa E. Murray, Nick C. Fox, Kerstin Sander, Michael Schöll
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/483bdb8b9982482da2936b48f6819fa4
Autor:
Feilin Liu, Dmytro Morderer, Melissa C. Wren, Sara A. Vettleson-Trutza, Yanzhe Wang, Benjamin E. Rabichow, Michelle R. Salemi, Brett S. Phinney, Björn Oskarsson, Dennis W. Dickson, Wilfried Rossoll
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract The most common inherited cause of two genetically and clinico-pathologically overlapping neurodegenerative diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), is the presence of expanded GGGGCC intronic hexanucl
Externí odkaz:
https://doaj.org/article/cc0660654eb34896bfeeff4293dda262
Autor:
Youn G. Shin, Dan Guo, Nicholas A. Payne, Brianna K. Rector, Kwang G. O’Donnell, Giles Whitaker, Jiju M. Joseph, Jungsook C. Wren
Publikováno v:
Physical Chemistry Chemical Physics. 25:2110-2130
Chemical waves that produce periodic patterns are common occurrences in nature. The underlying processes involved have been studied in many disciplines of science, but rarely reported in the chemistry of corrosion. In this study of carbon steel corro
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-16 (2018)
Abstract Imaging of pathological tau with positron emission tomography (PET) has the potential to allow early diagnosis of the dementias and monitoring of disease progression, including assessment of therapeutic interventions, in vivo. The first gene
Externí odkaz:
https://doaj.org/article/02cc5eb141d942d8934cb338b5252f3e
Autor:
Francesco Tres, Steven R. Coombes, Andrew R. Phillips, Leslie P. Hughes, Stephen A. C. Wren, Jonathan W. Aylott, Jonathan C. Burley
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 16404-16418 (2015)
We have investigated the dissolution performance of amorphous solid dispersions of poorly water-soluble bicalutamide in a Kollidon VA64 polymeric matrix as a function of the drug loading (5% vs. 30% bicalutamide). A combined suite of state-of-the-art
Externí odkaz:
https://doaj.org/article/9ce30c8dca73441c97f758253023d1d4
Autor:
Tammaryn Lashley, Kerstin Sander, Nick C. Fox, Steven Y Yap, Michael Schöll, Barbara Frias, Erik Årstad, Melissa C. Wren
Publikováno v:
Brain
A next generation of tau PET tracers for the imaging of Alzheimer’s disease and other dementias has recently been developed. Whilst the new compounds have now entered clinical studies, there is limited information available to assess their suitabil
Autor:
Yuan Fu, Lin Jia, Dennis W. Dickson, Mariet Allen, Jing Zhao, Akari Yamazaki, Takahisa Kanekiyo, Guojun Bu, Melissa C. Wren, Cynthia Linares, Yu Yamazaki, Lindsey M. Felton, Chia Chen Liu, Michael G. Heckman, Wenhui Qiao, Melissa E. Murray, Hongmei Li, Na Wang, Mary D. Davis, Nilufer Ertekin-Taner, Hiroshi Oue, Tomonori Aikawa, Minerva M. Carrasquillo, Ronald C. Petersen, Nancy N. Diehl, Na Zhao, Yonghe Li, Yuka A. Martens, Michael DeTure, Marie Louise Holm
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association
Introduction Cerebrovascular pathologies including cerebral amyloid angiopathy (CAA) and blood-brain barrier (BBB) dysregulation are prominent features in the majority of Alzheimer's disease (AD) cases. Methods We performed neuropathologic and bioche
Autor:
Hu Wang, Bradley F. Boeve, Michael G. Heckman, Yingxue Ren, Yan W. Asmann, Ana-Caroline Raulin, Yuan Fu, Thomas R. Caulfield, Tadafumi C. Ikezu, Tanis J. Ferman, Cynthia Linares, Lin Jia, Dennis W. Dickson, Carl Frieden, Jing Zhao, Owen A. Ross, Steven G. Younkin, Zbigniew K. Wszolek, Val J. Lowe, Cassandra L. Rosenberg, David S. Knopman, Xia Li, Yonghe Li, John D. Fryer, Xue Wang, Sydney V. Doss, Melissa E. Murray, Wenyan Lu, Clifford R. Jack, Melissa C. Wren, Xianlin Han, Joshua Knight, Zachary A. Trottier, Na Wang, Yuka A. Martens, Joseph E. Parisi, Yixing Chen, Guojun Bu, Aishe Kurti, Neill R. Graff-Radford, Kejal Kantarci, Chia Chen Liu, Glenn E. Smith, Ronald C. Petersen, Prashanthi Vemuri, Na Zhao, Francis Shue
Publikováno v:
BASE-Bielefeld Academic Search Engine
A rare APOE variant APOE3 -Jac reduces self-aggregation and promotes healthy brain aging.
Autor:
Laurence, Ted A., Negres, Raluca A., Feigenbaum, Eyal, Shen, Nan, Ly, Sonny, Alessi, David, Bude, Jeff D., Carr, C. Wren
Publikováno v:
Journal of Applied Physics; 2018, Vol. 124 Issue 8, pN.PAG-N.PAG, 9p, 1 Color Photograph, 9 Graphs