Zobrazeno 1 - 10
of 161
pro vyhledávání: '"A C, Scheck"'
Autor:
Richard E. Frye, Nicole Rincon, Patrick J. McCarty, Danielle Brister, Adrienne C. Scheck, Daniel A. Rossignol
Publikováno v:
Neurobiology of Disease, Vol 197, Iss , Pp 106520- (2024)
Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting 1 in 36 children and is associated with physiological abnormalities, most notably mitochondrial dysfunction, at least in a subset of individuals. This systematic review and met
Externí odkaz:
https://doaj.org/article/cf88aa418f524e4aabe503cd9675d6c0
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Background: Studies have linked autism spectrum disorder (ASD) to physiological abnormalities including mitochondrial dysfunction. Mitochondrial dysfunction may be linked to a subset of children with ASD who have neurodevelopmental regression (NDR).
Externí odkaz:
https://doaj.org/article/738c278f762d48b7afe7a2bf739c662b
Autor:
Nabil Hajji, Juan Garcia-Revilla, Manuel Sarmiento Soto, Richard Perryman, Jake Symington, Chad C. Quarles, Deborah R. Healey, Yijie Guo, Manuel Luis Orta-Vázquez, Santiago Mateos-Cordero, Khalid Shah, John Bomalaski, Giulio Anichini, Andreas G. Tzakos, Timothy Crook, Kevin O’Neill, Adrienne C. Scheck, Jose Luis Venero, Nelofer Syed
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)
New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that the efficacy of radiotherapy for GBM is strikingly potentiated by concomitant therapy with the arginine-depleting agent ADI-PEG20
Externí odkaz:
https://doaj.org/article/7a43ba7a6e2c46269a07eda280cc60bf
Autor:
Erica M. Rutter, Tracy L. Stepien, Barrett J. Anderies, Jonathan D. Plasencia, Eric C. Woolf, Adrienne C. Scheck, Gregory H. Turner, Qingwei Liu, David Frakes, Vikram Kodibagkar, Yang Kuang, Mark C. Preul, Eric J. Kostelich
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Five immunocompetent C57BL/6-cBrd/cBrd/Cr (albino C57BL/6) mice were injected with GL261-luc2 cells, a cell line sharing characteristics of human glioblastoma multiforme (GBM). The mice were imaged using magnetic resonance (MR) at five separ
Externí odkaz:
https://doaj.org/article/49c26a5cb0574efa92425851a3c1b035
Autor:
Evgenii Belykh, Eric J. Miller, Alessandro Carotenuto, Arpan A. Patel, Claudio Cavallo, Nikolay L. Martirosyan, Debbie R. Healey, Vadim A. Byvaltsev, Adrienne C. Scheck, Michael T. Lawton, Jennifer M. Eschbacher, Peter Nakaji, Mark C. Preul
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Previous studies showed that confocal laser endomicroscopy (CLE) images of brain tumors acquired by a first-generation (Gen1) CLE system using fluorescein sodium (FNa) contrast yielded a diagnostic accuracy similar to frozen surgical sect
Externí odkaz:
https://doaj.org/article/10af8008e0f840218f32622b14c5c89a
Autor:
Eric C. Woolf, Adrienne C. Scheck
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 1, Pp 5-10 (2015)
Advances in our understanding of glioma biology has led to an increase in targeted therapies in preclinical and clinical trials; however, cellular heterogeneity often precludes the targeted molecules from being found on all glioma cells, thus reducin
Externí odkaz:
https://doaj.org/article/30d0c94f92bc4207909efbd26c5160ff
Autor:
Hao Yan, Jonas Gopez, Steven S. Yocom, Xiaodong Qi, Joseph Georges, Denah M. Appelt, Mark C. Preul, Evgenii Belykh, Jennifer Eschbacher, Yu Zhou, Trent Anderson, Zein Al-Atrache, Eric C. Woolf, Adrienne C. Scheck, Amber Valeri, Xiaowei Liu, Burt G. Feuerstein, Peter Nakaji, Mark Reiser
Publikováno v:
Journal of Neurosurgery. 134:1783-1790
OBJECTIVE Differentiating central nervous system (CNS) lymphoma from other intracranial malignancies remains a clinical challenge in surgical neuro-oncology. Advances in clinical fluorescence imaging contrast agents and devices may mitigate this chal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69fe6a0291c75f792c3c3abeaf988a8
https://doi.org/10.3171/2020.4.jns192476
https://doi.org/10.3171/2020.4.jns192476
Autor:
Irena, Voinsky, Yazeed, Zoabi, Noam, Shomron, Moria, Harel, Hanoch, Cassuto, Joseph, Tam, Shannon, Rose, Adrienne C, Scheck, Mohammad A, Karim, Richard E, Frye, Adi, Aran, David, Gurwitz
Publikováno v:
International journal of molecular sciences. 23(17)
Mutations in over 100 genes are implicated in autism spectrum disorder (ASD). DNA SNPs, CNVs, and epigenomic modifications also contribute to ASD. Transcriptomics analysis of blood samples may offer clues for pathways dysregulated in ASD. To expand a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3d0a36d1221479e39af5c9dbd41505b
https://pubmed.ncbi.nlm.nih.gov/36077244
https://pubmed.ncbi.nlm.nih.gov/36077244
Autor:
Ahmad K. Almekkawi, Marwa W. AlJardali, Hicham M. Daadaa, Alison L. Lane, Ashley R. Worner, Mohammad A. Karim, Adrienne C. Scheck, Richard E. Frye
Publikováno v:
Journal of personalized medicine. 12(10)
Neural tube defects (NTDs) are congenital abnormalities in the central nervous system. The exact etiology of NTDs is still not determined, but several genetic and epigenetic factors have been studied. Folate supplementation during gestation is recomm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9e3fb373d72928d1ea0b22d0308c45
https://pubmed.ncbi.nlm.nih.gov/36294748
https://pubmed.ncbi.nlm.nih.gov/36294748
Autor:
Peter Nakaji, Deborah R. Healey, C. Chad Quarles, Jennifer M. Eschbacher, Mark C. Preul, L. A. Bardonova, Jubran H. Jubran, Shwetal Mehta, Joseph Georges, Laeth George, Evgenii Belykh, Adrienne C. Scheck
Publikováno v:
Molecular Imaging and Biology. 23:586-596
This study evaluated the use of molecular imaging of fluorescent glucose analog 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) as a discriminatory marker for intraoperative tumor border identification in a murine glioma model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3524fd11f056c33d4b95a44054525f1e
https://doi.org/10.1007/s11307-021-01579-z
https://doi.org/10.1007/s11307-021-01579-z