Zobrazeno 1 - 10
of 312
pro vyhledávání: '"A C, Montezano"'
Autor:
Augusto C. Montezano, Livia L. Camargo, Sheon Mary, Karla B Neves, Francisco J Rios, Ross Stein, Rheure A. Lopes, Wendy Beattie, Jacqueline Thomson, Vanessa Herder, Agnieszka M. Szemiel, Steven McFarlane, Massimo Palmarini, Rhian M. Touyz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract COVID-19, caused by SARS-CoV-2, is a respiratory disease associated with inflammation and endotheliitis. Mechanisms underling inflammatory processes are unclear, but angiotensin converting enzyme 2 (ACE2), the receptor which binds the spike
Externí odkaz:
https://doaj.org/article/e05cdc1398a34aa49f53b13c0a5c14a8
Autor:
Francisco J. Rios, Zhi-Guo Zou, Adam P. Harvey, Katie Y. Harvey, Livia L. Camargo, Karla B. Neves, Sarah E. F. Nichol, Rheure Alves-Lopes, Alexius Cheah, Maram Zahraa, Alexey G. Ryazanov, Lillia Ryazanova, Thomas Gudermann, Vladimir Chubanov, Augusto C. Montezano, Rhian M. Touyz
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Deficiency of the Mg2+-permeable channel/α-kinase TRPM7 in mice increases susceptibility to cardiovascular and renal fibrosis induced by aldosterone and salt.
Externí odkaz:
https://doaj.org/article/cb2321b1b4554eefad7adf3bec82bdc7
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 4 (2023)
Background Hypertension and vascular toxicity are major unwanted side effects of antiangiogenic drugs, such as vascular endothelial growth factor inhibitors (VEGFis), which are effective anticancer drugs but have unwanted side effects, including vasc
Externí odkaz:
https://doaj.org/article/6089b32e18e5405fb80461c46b9b1abd
Autor:
Rhian M. Touyz, MBBCh, PhD, Marcus O.E. Boyd, Tomasz Guzik, MD, PhD, Sandosh Padmanabhan, MD, PhD, Linsay McCallum, MBChB, Christian Delles, MD, Patrick B. Mark, MBChB, PhD, John R. Petrie, MBChB, PhD, Francisco Rios, PhD, Augusto C. Montezano, PhD, Robert Sykes, MBChB, BMedSci, Colin Berry, MBChB, PhD
Publikováno v:
CJC Open, Vol 3, Iss 10, Pp 1257-1272 (2021)
The current COVID-19 pandemic, caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) virus, represents the largest medical challenge in decades. It has exposed unexpected cardiovascular vulnerabilities at all stages of the diseas
Externí odkaz:
https://doaj.org/article/205e4aaccaf14a2e9d150cee55473849
Autor:
Alan C. Cameron, MBChB, PhD, Kelly McMahon, BSc, Mark Hall, MBChB, Karla B. Neves, PhD, Francisco J. Rios, PhD, Augusto C. Montezano, PhD, Paul Welsh, PhD, Ashita Waterston, MBChB, PhD, Jeff White, MBChB, DM, Patrick B. Mark, MBChB, PhD, Rhian M. Touyz, MBBCh, PhD, Ninian N. Lang, MBChB, PhD
Publikováno v:
JACC. CardioOncology, Vol 2, Iss 3, Pp 443-455 (2020)
Background: Cisplatin-based chemotherapy increases the risk of cardiovascular and renal disease. Objectives: We aimed to define the time course, pathophysiology, and approaches to prevent cardiovascular disease associated with cisplatin-based chemoth
Externí odkaz:
https://doaj.org/article/0d964defbf61439cbf51ef4f12911b48
Autor:
Giacomo Rossitto, Sheon Mary, Jun Yu Chen, Philipp Boder, Khai Syuen Chew, Karla B. Neves, Rheure L. Alves, Augusto C. Montezano, Paul Welsh, Mark C. Petrie, Delyth Graham, Rhian M. Touyz, Christian Delles
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Na+ has been suggested to accumulate in tissues, particularly skin, in a hypertonic manner and to exert local pathogenic effects. Here, we reappraise this phenomenon which is systemic in nature and reflects isotonic changes in the relative extracellu
Externí odkaz:
https://doaj.org/article/00f4143ef72e4165a258bfd5a79eca0e
Autor:
Amit Mahindra, Gonzalo Tejeda, Mario Rossi, Omar Janha, Imogen Herbert, Caroline Morris, Danielle C. Morgan, Wendy Beattie, Augusto C. Montezano, Brian Hudson, Andrew B. Tobin, David Bhella, Rhian M. Touyz, Andrew G. Jamieson, George S. Baillie, Connor M. Blair
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
SARS-CoV-2 viral attachment and entry into host cells is mediated by a direct interaction between viral spike glycoproteins and membrane bound angiotensin-converting enzyme 2 (ACE2). The receptor binding motif (RBM), located within the S1 subunit of
Externí odkaz:
https://doaj.org/article/f0f07f9a6ed44895934fa969a58c9b5e
Autor:
Aurelie Nguyen Dinh Cat, Glaucia E. Callera, Malou Friederich-Persson, Ana Sanchez, Maria Gabriela Dulak-Lis, Sofia Tsiropoulou, Augusto C. Montezano, Ying He, Ana M. Briones, Frederic Jaisser, Rhian M. Touyz
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Activation of aldosterone/mineralocorticoid receptors (MR) has been implicated in vascular dysfunction of diabetes. Underlying mechanisms are elusive. Therefore, we investigated the role of Rho kinase (ROCK) in aldosterone/MR signaling and v
Externí odkaz:
https://doaj.org/article/1cbc4ec98c8b49dfb0ee07f4993edd82
Autor:
Robert A Sykes, Karla B Neves, Rhéure Alves-Lopes, Ilaria Caputo, Kirsty Fallon, Nigel B Jamieson, Anna Kamdar, Assya Legrini, Holly Leslie, Alasdair McIntosh, Alex McConnachie, Andrew Morrow, Richard W McFarlane, Kenneth Mangion, John McAbney, Augusto C Montezano, Rhian M Touyz, Colin Wood, Colin Berry
Publikováno v:
European Heart Journal - Cardiovascular Pharmacotherapy.
Background In post-coronavirus disease-19 (post-COVID-19) conditions (long COVID), systemic vascular dysfunction is implicated, but the mechanisms are uncertain, and the treatment is imprecise. Methods and results Patients convalescing after hospital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e72648f1befba38972702959d190538
https://doi.org/10.1093/ehjcvp/pvad025
https://doi.org/10.1093/ehjcvp/pvad025
Autor:
Katrina M. Mirabito Colafella, Daan C.H. van Dorst, Rugina I. Neuman, Leni van Doorn, Karla Bianca Neves, Augusto C. Montezano, Ingrid M. Garrelds, Richard van Veghel, René de Vries, Estrellita Uijl, Marian C. Clahsen-van Groningen, Hans J. Baelde, Anton H. van den Meiracker, Rhian M. Touyz, Willy Visser, A.H. Jan Danser, Jorie Versmissen
Publikováno v:
Clinical Science, 136(9), 675-694. Portland Press, Ltd.
Vascular endothelial growth factor antagonism with angiogenesis inhibitors in cancer patients induces a ‘preeclampsia-like’ syndrome including hypertension, proteinuria and elevated endothelin (ET)-1. Cyclo-oxygenase (COX) inhibition with aspirin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7df56cbeb197a64f26da4435f5916e
http://www.scopus.com/inward/record.url?scp=85131225793&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85131225793&partnerID=8YFLogxK