Zobrazeno 1 - 10
of 10
pro vyhledávání: '"A C, Molijn"'
Autor:
Lisanne, Verhoef, Maaike C G, Bleeker, Nicole, Polman, Renske D M, Steenbergen, Chris J L M, Meijer, Willem J G, Melchers, Ruud L, Bekkers, Anco C, Molijn, Wim G, Quint, Folkert J, van Kemenade, Johannes, Berkhof, Daniëlle A M, Heideman
Publikováno v:
International Journal of Cancer. 150(3):440-449
Methylation of host-cell deoxyribonucleic acid (DNA) has been proposed as a promising biomarker for triage of high-risk (hr) human papillomavirus (HPV) positive women at screening. Our study aims to validate recently identified host-cell DNA methylat
Autor:
Lisanne Verhoef, Maaike C. G. Bleeker, Nicole Polman, Renske D. M. Steenbergen, Renée M. F. Ebisch, Willem J. G. Melchers, Ruud L. M. Bekkers, Anco C. Molijn, Wim G. Quint, Folkert van Kemenade, Chris J. L. M. Meijer, Johannes Berkhof, Daniëlle A. M. Heideman
Publikováno v:
British Journal of Cancer. Nature Publishing Group
British Journal of Cancer, 129, 1, pp. 104-111
Verhoef, L, Bleeker, M C G, Polman, N, Steenbergen, R D M, Ebisch, R M F, Melchers, W J G, Bekkers, R L M, Molijn, A C, Quint, W G, van Kemenade, F, Meijer, C J L M, Berkhof, J & Heideman, D A M 2023, ' Evaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening ', British Journal of Cancer, vol. 129, no. 1, pp. 104-111 . https://doi.org/10.1038/s41416-023-02277-z
British Journal of Cancer, 129, 1, pp. 104-111
Verhoef, L, Bleeker, M C G, Polman, N, Steenbergen, R D M, Ebisch, R M F, Melchers, W J G, Bekkers, R L M, Molijn, A C, Quint, W G, van Kemenade, F, Meijer, C J L M, Berkhof, J & Heideman, D A M 2023, ' Evaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening ', British Journal of Cancer, vol. 129, no. 1, pp. 104-111 . https://doi.org/10.1038/s41416-023-02277-z
Background Host-cell DNA methylation analysis can be used to triage women with high-risk human papillomavirus (HPV)-positive self-collected cervicovaginal samples, but current data are restricted to under-/never-screened women and referral population
Autor:
Gerard Grosveld, Magda A. Meester-Smoor, Ellen C. Zwarthoff, Nicole A. Groen, Diny van Dalsum-Verbiest, Yixian Zhao, Cora A.H. Groffen, Anco C. Molijn, Merel W. Boogaard
Publikováno v:
Journal of Molecular Endocrinology. 38(1-2):113-125
The IGF-binding protein (IGFBP) family consists of six proteins that are expressed and secreted in different tissues. The proteins are regulators of physiological processes throughout the body by modulating the activity of IGF-I and IGF-II. In this a
Autor:
Gerard Grosveld, Arjan Buijs, Karel H. M. van Wely, Magda A. Meester-Smoor, Albert Jan Aarnoudse, Anita Hellemons, Ellen C. Zwarthoff, Pim den Besten, Anco C. Molijn
Publikováno v:
Oncogene. 22:699-709
The t(12;22) creates an MN1-TEL fusion gene leading to acute myeloid leukemia. The fusion partner TEL (ETV6) is a member of the ETS family of transcription factors. The nature of the other fusion partner, MN1, has not been investigated in detail unti
Autor:
E.C. Zwarthoff, M A den Bakker, Kees J. Vissers, Johan M. Kros, A C Molijn, T.H. Van Der Kwast
Publikováno v:
Journal of Histochemistry & Cytochemistry. 47:1471-1479
The neurofibromatosis Type 2 tumor suppressor gene is implicated in the hereditary tumor syndrome NF2, hallmarked by bilateral vestibular schwannomas, meningiomas, and ocular non-neoplastic features. The gene product has characteristics of a membrane
Autor:
A.-L. Börresen, W. J. F. De Leeuw, A. G. Uitterlinden, Jan Vijg, A. Verwest, A. C. Molijn, Tone Ikdahl Andersen, Erik Mullaart
Publikováno v:
British Journal of Cancer
We have recently used two-dimensional DNA typing to detect genetic alterations in breast tumours. This method, which is based on size separation in neutral gels and sequence separation in denaturing gradient gels followed by hybridisation analysis wi
Autor:
Ellen C. Zwarthoff, Magda A. Meester-Smoor, Karel H. M. van Wely, A. C. P. Hekman, Marcel Vermeij, Christl Vermey-Keers, Marjolein J. L. van Helmond, Anco C. Molijn, Peter Riegman
Publikováno v:
Molecular and Cellular Biology, 25(10), 4229-4236. American Society for Microbiology
Fusion of the MN1 gene to TEL (ETV6) results in myeloid leukemia. The fusion protein combines the transcription activating domain of MN1 and the DNA binding domain of TEL and is thought to act as a deranged transcription factor. In addition, disrupti
Autor:
Martine F. Roussel, Mark D. Potter, Alfred C.O. Vertegaal, Gerard Grosveld, Anco C. Molijn, J. Nathan Davis, Sjozef van Baal, Constantin Adams, Luc Van Rompaey, Ellen C. Zwarthoff, Arjan Buijs
Publikováno v:
Molecular and Cellular Biology, 20(24), 9281-9293. American Society for Microbiology
The Tel gene (or ETV6) is the target of the translocation (12;22)(p13;q11) in myeloid leukemia. TEL is a member of the ETS family of transcription factors and contains the pointed protein interaction (PNT) domain and an ETS DNA binding domain (DBD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d6ff4f760fc1a291c3925d795a78ac
https://pure.eur.nl/en/publications/19c6c18e-aaf8-408f-aeae-72514b971685
https://pure.eur.nl/en/publications/19c6c18e-aaf8-408f-aeae-72514b971685
Publikováno v:
EMBO Journal, 12(6), 2275-2279. Wiley
Recently, interest in the enzyme nucleoside diphosphate kinase (EC2.7.4.6) has increased as a result of its possible involvement in cell proliferation and development. Since NDP kinase is one of the major sources of GTP in cells, it has been suggeste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e8a032ef60972a80da6c2e02f49322
https://research.rug.nl/en/publications/9aebfb21-8775-4412-8821-ae7f518bd0a4
https://research.rug.nl/en/publications/9aebfb21-8775-4412-8821-ae7f518bd0a4
Publikováno v:
BioTechniques. 14(4)
A method for the efficient rescue of lac operator containing plasmids from transgenic mouse genomic DNA is described. The method is based on the high affinity of the LacI repressor protein for the lac operator sequence. Using the LacI repressor prote