Zobrazeno 1 - 10
of 298
pro vyhledávání: '"A C, Marriott"'
Polymeric nanoparticle-based mRNA vaccine is protective against influenza virus infection in ferrets
Autor:
Gijs Hardenberg, Chantal Brouwer, Rachelle van Gemerden, Nicola J. Jones, Anthony C. Marriott, Jaap Rip
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102159- (2024)
New therapies and vaccines based on nucleic acids combined with an efficient nanoparticle delivery vehicle have a broad applicability for different disease indications. An alternative delivery technology for the successfully applied lipid nanoparticl
Externí odkaz:
https://doaj.org/article/d1792e088a2e4ea4861b97eb69022cf8
Autor:
Jemma Paterson, Kathryn A. Ryan, Daniel Morley, Nicola J. Jones, Paul Yeates, Yper Hall, Catherine J. Whittaker, Francisco J. Salguero, Anthony C. Marriott
Publikováno v:
Pathogens, Vol 12, Iss 5, p 668 (2023)
Animal models of influenza are important in preclinical research for the study of influenza infection and the assessment of vaccines, drugs and therapeutics. Here, we show that Golden Syrian hamsters (Mesocricetus auratus) inoculated via the intranas
Externí odkaz:
https://doaj.org/article/768b52275713427da4dcd8754bf979cd
Autor:
K. Wilkinson, J. Day, J. Thompson-Coon, V. Goodwin, K. Liabo, G. Coxon, G. Cox, C. Marriott, I. A. Lang
Publikováno v:
Research Involvement and Engagement, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Background Collaborative working between academic institutions and those who provide health and social care has been identified as integral in order to produce acceptable, relevant, and timely research, and for outputs to be useful and pract
Externí odkaz:
https://doaj.org/article/c9339b0722674c2ba03badc35f14adf7
Autor:
Anthony C. Marriott, Karen E. Gooch, Phillip J. Brown, Kathryn A. Ryan, Nicola J. Jones, Natasha Merredew, Nathan Wiblin, Oliver Dibben, Helen Bright, Bassam Hallis, Catherine J. Whittaker, Miles W. Carroll
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-8 (2021)
Abstract Live attenuated influenza vaccine (LAIV) is widely used to protect humans from seasonal influenza infection, particularly in children. In contrast to inactivated vaccines, the LAIV can induce both mucosal and cellular immune responses. Here
Externí odkaz:
https://doaj.org/article/f9f97dcbeef94e3ca43053085c7250dd
Autor:
Kathryn A. Ryan, Kevin R. Bewley, Susan A. Fotheringham, Gillian S. Slack, Phillip Brown, Yper Hall, Nadina I. Wand, Anthony C. Marriott, Breeze E. Cavell, Julia A. Tree, Lauren Allen, Marilyn J. Aram, Thomas J. Bean, Emily Brunt, Karen R. Buttigieg, Daniel P. Carter, Rebecca Cobb, Naomi S. Coombes, Steve J. Findlay-Wilson, Kerry J. Godwin, Karen E. Gooch, Jade Gouriet, Rachel Halkerston, Debbie J. Harris, Thomas H. Hender, Holly E. Humphries, Laura Hunter, Catherine M. K. Ho, Chelsea L. Kennard, Stephanie Leung, Stephanie Longet, Didier Ngabo, Karen L. Osman, Jemma Paterson, Elizabeth J. Penn, Steven T. Pullan, Emma Rayner, Oliver Skinner, Kimberley Steeds, Irene Taylor, Tom Tipton, Stephen Thomas, Carrie Turner, Robert J. Watson, Nathan R. Wiblin, Sue Charlton, Bassam Hallis, Julian A. Hiscox, Simon Funnell, Mike J. Dennis, Catherine J. Whittaker, Michael G. Catton, Julian Druce, Francisco J. Salguero, Miles W. Carroll
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
SARS-CoV-2 induces mild infection in ferret model. Here, Ryan et al. characterise optimal infection dosage inducing upper respiratory tract (UTR) viral shedding, progression time of viral shedding, and pathology in ferrets and finally provide evidenc
Externí odkaz:
https://doaj.org/article/a8afc90cbc2f4422be7dc5bc8923c3cf
Autor:
Bo Meng, Kirsten Bentley, Anthony C. Marriott, Paul D. Scott, Nigel J. Dimmock, Andrew J. Easton
Publikováno v:
Virology Journal, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Defective interfering (DI) viruses are natural antivirals made by nearly all viruses. They have a highly deleted genome (thus being non-infectious) and interfere with the replication of genetically related infectious viruses. We h
Externí odkaz:
https://doaj.org/article/91dd5b94af694986a7a8432413453e6f
Autor:
M. D Heath, N. J. Swan, A. C. Marriott, N. J. Silman, B. Hallis, C. Prevosto, K. E. Gooch, M. A. Skinner
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Vaccination against seasonal influenza strains is recommended for “high risk” patient groups such as infants, elderly and those with respiratory or circulatory diseases. However, efficacy of the trivalent influenza vaccine (TI
Externí odkaz:
https://doaj.org/article/74c6227431644a2f83b8a45b1af52176
Autor:
Kathryn A Ryan, Gillian S Slack, Anthony C Marriott, Jennifer A Kane, Catherine J Whittaker, Nigel J Silman, Miles W Carroll, Karen E Gooch
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202675 (2018)
Seasonal influenza virus infections cause yearly epidemics which are the source of a significant public health burden worldwide. The ferret model for human influenza A virus (IAV) is widely used and has several advantages over other animal models suc
Externí odkaz:
https://doaj.org/article/5e55374e2631474e9aa403c22a5cd93f
Autor:
Kathryn A Ryan, Katarzyna E Schewe, Jonathan Crowe, Susan A Fotheringham, Yper Hall, Richard Humphreys, Anthony C Marriott, Jemma Paterson, Emma Rayner, Francisco J Salguero, Robert J Watson, Catherine J Whittaker, Miles W Carroll, Oliver Dibben
Publikováno v:
The Journal of Infectious Diseases. 225:404-412
Cocirculation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses could pose unpredictable risks to health systems globally, with recent studies suggesting more severe disease outcomes in coinfected patients. The ini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce29ba68b8706c4b49fad8ae732d41b5
https://doi.org/10.1093/infdis/jiab594
https://doi.org/10.1093/infdis/jiab594
Autor:
Morgan C. Marriott, Michael A. Smith
Purpose: Pain is experienced by over half of patients with cancer. Despite effective treatments being available, many patients with cancer related pain remain undertreated. Chronic overlapping pain conditions (COPCs) are recognized as a set of disord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1990753167195f4d69f4ba42ba91fb
https://doi.org/10.21203/rs.3.rs-1678297/v1
https://doi.org/10.21203/rs.3.rs-1678297/v1
