Zobrazeno 1 - 10
of 239
pro vyhledávání: '"A C, Hargreaves"'
Publikováno v:
Climate of the Past, Vol 20, Pp 1989-1999 (2024)
We present a reconstruction of the surface climate of the mid-Pliocene Warm Period (mPWP), specifically Marine Isotope Stage (MIS) KM5c or 3.205 Ma. We combine the ensemble of climate model simulations, which contributed to the Pliocene Model Interco
Externí odkaz:
https://doaj.org/article/c6dab42346384f9999eee3d2ec17b595
Autor:
Elizabeth J Burns, Frank de Vocht, Noemia Siqueira, Cathy Ure, Suzanne Audrey, Margaret Coffey, Susan Hare, Suzy C Hargreaves, Mira Hidajat, Steve Parrott, Lauren Scott, Penny A Cook
Publikováno v:
Public Health Research, Vol 12, Iss 09 (2024)
Background Globally alcohol consumption is a leading risk factor for premature death and disability and is associated with crime, social and economic consequences. Local communities may be able to play a role in addressing alcohol-related issues in t
Externí odkaz:
https://doaj.org/article/ae33eef007744295ad171def000a4b0c
Autor:
L. Paige Ferguson, Jovylyn Gatchalian, Matthew L. McDermott, Mari Nakamura, Kendall Chambers, Nirakar Rajbhandari, Nikki K. Lytle, Sara Brin Rosenthal, Michael Hamilton, Sonia Albini, Martin Wartenberg, Inti Zlobec, José A. Galván, Eva Karamitopoulou, Vera Vavinskaya, Alexis Wascher, Andrew M. Lowy, Christian M. Schürch, Pier Lorenzo Puri, Benoit G. Bruneau, Diana C. Hargreaves, Tannishtha Reya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Clinical management of pancreatic cancer remains challenging. Here, the authors suggest SMARCD3 as a potential epigenetic dependency establishing the metabolic landscape in aggressive pancreatic cancer cells and as a potential therapeutic target in p
Externí odkaz:
https://doaj.org/article/eadb3f5725a947ddb9882b3a7d976ccc
Autor:
Elizabeth J. Burns, Suzy C. Hargreaves, Cathy Ure, Susan Hare, Margaret Coffey, Mira Hidajat, Suzanne Audrey, Frank de Vocht, Kate Ardern, Penny A. Cook
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background It is widely recognised that complex public health interventions roll out in distinct phases, within which external contextual factors influence implementation. Less is known about relationships with external contextual factors id
Externí odkaz:
https://doaj.org/article/bd264a52fc6c4940969c2adeadc0e93d
Publikováno v:
Climate of the Past, Vol 18, Pp 1883-1896 (2022)
We present a new reconstruction of surface air temperature and sea surface temperature for the Last Glacial Maximum. The method blends model fields and sparse proxy-based point estimates through a data assimilation approach. Our reconstruction update
Externí odkaz:
https://doaj.org/article/5f512094ca5a4e24995a75efcba024e6
Autor:
C. M. Brierley, A. Zhao, S. P. Harrison, P. Braconnot, C. J. R. Williams, D. J. R. Thornalley, X. Shi, J.-Y. Peterschmitt, R. Ohgaito, D. S. Kaufman, M. Kageyama, J. C. Hargreaves, M. P. Erb, J. Emile-Geay, R. D'Agostino, D. Chandan, M. Carré, P. J. Bartlein, W. Zheng, Z. Zhang, Q. Zhang, H. Yang, E. M. Volodin, R. A. Tomas, C. Routson, W. R. Peltier, B. Otto-Bliesner, P. A. Morozova, N. P. McKay, G. Lohmann, A. N. Legrande, C. Guo, J. Cao, E. Brady, J. D. Annan, A. Abe-Ouchi
Publikováno v:
Climate of the Past, Vol 16, Pp 1847-1872 (2020)
The mid-Holocene (6000 years ago) is a standard time period for the evaluation of the simulated response of global climate models using palaeoclimate reconstructions. The latest mid-Holocene simulations are a palaeoclimate entry card for the Palaeocl
Externí odkaz:
https://doaj.org/article/e4dd0c3bc4bf4b52a7516287f6ef76cc
Autor:
M. Renoult, J. D. Annan, J. C. Hargreaves, N. Sagoo, C. Flynn, M.-L. Kapsch, Q. Li, G. Lohmann, U. Mikolajewicz, R. Ohgaito, X. Shi, Q. Zhang, T. Mauritsen
Publikováno v:
Climate of the Past, Vol 16, Pp 1715-1735 (2020)
In this paper we introduce a Bayesian framework, which is explicit about prior assumptions, for using model ensembles and observations together to constrain future climate change. The emergent constraint approach has seen broad application in recent
Externí odkaz:
https://doaj.org/article/bb763e62ba1443daaf9f3c57b8232b94
Publikováno v:
Earth System Dynamics, Vol 11, Pp 709-719 (2020)
We examine what can be learnt about climate sensitivity from variability in the surface air temperature record over the instrumental period, from around 1880 to the present. While many previous studies have used trends in observational time series to
Externí odkaz:
https://doaj.org/article/4a3cda1f3a3b4537a0bf8928f70238e6
Autor:
J. D. Annan, J. C. Hargreaves
Publikováno v:
Earth System Dynamics, Vol 11, Pp 347-356 (2020)
Observational constraints on the equilibrium climate sensitivity have been generated in a variety of ways, but a number of results have been calculated which appear to be based on somewhat informal heuristics. In this paper we demonstrate that many o
Externí odkaz:
https://doaj.org/article/9816a83fd1a54477ac0e0abfe8f576c3
Autor:
Jovylyn Gatchalian, Shivani Malik, Josephine Ho, Dong-Sung Lee, Timothy W. R. Kelso, Maxim N. Shokhirev, Jesse R. Dixon, Diana C. Hargreaves
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The BAF complex is a multi-subunit chromatin remodeling complex that plays important roles in transcription regulation. Here the authors provide evidence that BRD9 and GLTSCR1/BICRA or its paralog GLTSCR1-like/BICRAL define a non-canonical BAF comple
Externí odkaz:
https://doaj.org/article/68252e2a987241adafd12cb3fa6d9025