Zobrazeno 1 - 10
of 3 521
pro vyhledávání: '"A C, Davies"'
Autor:
Abhinav Thakral, John JW. Lee, Tianzhichao Hou, Katrina Hueniken, Tom Dudding, Mark Gormley, Shama Virani, Andrew Olshan, Brenda Diergaarde, Andrew R. Ness, Tim Waterboer, Karl Smith-Byrne, Paul Brennan, D. Neil Hayes, Eleanor Sanderson, M. Catherine Brown, Sophie Huang, Scott V. Bratman, Anna Spreafico, John De Almeida, Joel C. Davies, Laura Bierut, Gary J. Macfarlane, Pagona Lagiou, Areti Lagiou, Jerry Polesel, Antonio Agudo, Laia Alemany, Wolfgang Ahrens, Claire M. Healy, David I. Conway, Mari Nygard, Cristina Canova, Ivana Holcatova, Lorenzo Richiardi, Ariana Znaor, David P. Goldstein, Rayjean J. Hung, Wei Xu, Geoffrey Liu, Osvaldo Espin-Garcia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are recognized as distinct entities. There remains uncertainty surrounding the causal effects of smoking and alcohol on the development of these two cancer types. He
Externí odkaz:
https://doaj.org/article/d3d477a5f0674925ba9467f628ee8ad5
Autor:
Marcus A. Mall, Jane C. Davies, Scott H. Donaldson, Raksha Jain, James D. Chalmers, Michal Shteinberg
Publikováno v:
European Respiratory Review, Vol 33, Iss 173 (2024)
Chronic airway inflammation is a central feature in the pathogenesis of bronchiectasis (BE), which can be caused by cystic fibrosis (CFBE; hereafter referred to as CF lung disease) and non-CF-related conditions (NCFBE). Inflammation in both CF lung d
Externí odkaz:
https://doaj.org/article/dfe8670288044c5e84abe9bacbdda189
Autor:
Huw C. Davies, Michael Sprenger
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 13, Pp n/a-n/a (2024)
Abstract Distinctive synoptic‐scale (∼1,500 km) flow features are identified within the core of the stratospheric polar‐night vortex at stratopause altitudes (∼50 km). Typically they comprise a train or a complex pattern of transient vortices
Externí odkaz:
https://doaj.org/article/bab43847717141539a249d25a4440c84
Autor:
Jessie Matthews, Rebecca Dobra, Gemma Wilson, Lucy Allen, Cara Bossley, Rebecca Brendell, Rossa Brugha, Danielle Brown, Sarah Brown, Shenna Cadiente, Loren Cameron, Gwyneth Davies, Charlotte Dawson, Stuart Elborn, Dominic Hughes, Jess Longmate, Patricia Macedo, Leonidas Pappas, Caroline Pao, Chris Round, Gary Ruiz, Clare Saunders, Nadia Shafi, Nicholas Simmonds, Michael Waller, Danie Watson, Jane C. Davies
Publikováno v:
Contemporary Clinical Trials Communications, Vol 39, Iss , Pp 101301- (2024)
Cystic fibrosis (CF) is a multisystem, genetic disease with a significantly reduced life expectancy. Despite substantial progress in therapies in the last 10–15 years, there is still no cure. There are dozens of drugs in the development pipeline an
Externí odkaz:
https://doaj.org/article/d52c7039d18d43d3b37c2fcbc553d08b
Autor:
Emily Chesshyre, Fiona C. Warren, Angela C. Shore, Jane C. Davies, Darius Armstrong-James, Adilia Warris
Publikováno v:
Journal of Fungi, Vol 10, Iss 9, p 599 (2024)
Observational studies indicate that Aspergillus colonization and allergic bronchopulmonary aspergillosis (ABPA) in people with cystic fibrosis (CF) are associated with poorer lung health and increased disease severity. We performed a longitudinal obs
Externí odkaz:
https://doaj.org/article/7a3851802f7d45e689e90d09fda8e59d
Autor:
Paul McNally, Barry Linnane, Michael Williamson, Basil Elnazir, Christopher Short, Clare Saunders, Laura Kirwan, Rea David, Mariette P. C. Kemner-Van de Corput, Harm A.W.M. Tiddens, Jane C Davies, Des W Cox
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background Data from clinical trials of lumacaftor-ivacaftor (LUM-IVA) demonstrate improvements in lung clearance index (LCI) but not in FEV1 in children with Cystic Fibrosis (CF) aged 6–11 years and homozygous for the Phe508del mutation.
Externí odkaz:
https://doaj.org/article/d411190115bd499ebad07591cb91a617
Autor:
Venkata K. Yellepeddi, Marco Battaglia, Simon J. C. Davies, Jeremiah Alt, Shaelene Ashby, Paige Shipman, David J. Anderson, Joseph E. Rower, Christopher Reilly, Michael Voight, Sabiha Rahman Mim
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 6, Pp 1075-1084 (2023)
Abstract Anxiety and panic disorders are the most common mental illnesses in the United States and lack effective treatment options. Acid‐sending ion channels (ASICs) in the brain were shown to be associated with fear conditioning and anxiety respo
Externí odkaz:
https://doaj.org/article/ecb939b59a264699b045dde98bd00890
Autor:
Shruthi Kalgudde Gopal, Ruoxuan Dai, Ania Maria Stefanska, Meshal Ansari, Jiakuan Zhao, Pushkar Ramesh, Johannes W. Bagnoli, Donovan Correa-Gallegos, Yue Lin, Simon Christ, Ilias Angelidis, Valerio Lupperger, Carsten Marr, Lindsay C. Davies, Wolfgang Enard, Hans-Günther Machens, Herbert B. Schiller, Dongsheng Jiang, Yuval Rinkevich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The origins of wound myofibroblasts and scar tissue remains unclear, but it is assumed to involve conversion of adipocytes into myofibroblasts. Here, we directly explore the potential plasticity of adipocytes and fibroblasts after skin injur
Externí odkaz:
https://doaj.org/article/555bd59cdc42402d93754aed435aa3b6
Autor:
Kerry Newbrook, Nakibul Khan, Aimee Fisher, Karen Chong, Simon Gubbins, William C. Davies, Christopher Sanders, Marc Guimerà Busquets, Lyndsay Cooke, Amanda Corla, Martin Ashby, John Flannery, Carrie Batten, Jessica E. Stokes, Beatriz Sanz-Bernardo, Simon Carpenter, Katy Moffat, Karin E. Darpel
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionBluetongue virus (BTV) is an arthropod-borne Orbivirus that is almost solely transmitted by Culicoides biting midges and causes a globally important haemorrhagic disease, bluetongue (BT), in susceptible ruminants. Infection with BTV is ch
Externí odkaz:
https://doaj.org/article/a04ad604f145446ba0ff87a600ab207f
Autor:
S. Stetkiewicz, J. Menary, A. Nair, M. Rufino, A. R. H. Fischer, M. Cornelissen, A. Guichaoua, P. Jorasch, S. Lemarié, A. K. Nanda, R. Wilhelm, J. A. C. Davies
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Crop improvement is a key innovation area in the pursuit of sustainable food systems. However, realising its potential requires integration of the needs and priorities of all agri-food chain stakeholders. In this study, we provide a multi-st
Externí odkaz:
https://doaj.org/article/465ac9cf99d54a26b8ae7b418a1bf0b9