Zobrazeno 1 - 10
of 929
pro vyhledávání: '"A Bottomly"'
Autor:
Michael J. Caplan, Richard Baldwin, Xiangyun Yin, Alexander Grishin, Stephanie Eisenbarth, Hugh A. Sampson, Kim Bottomly, Robert K. Prud’homme
Publikováno v:
Communications Materials, Vol 5, Iss 1, Pp 1-11 (2024)
Abstract Immune modulation and desensitization is a growing field of research and clinical investigation that requires precise delivery of antigens to immune system cells. Nanoparticles (NPs) have emerged as excellent candidates for antigen delivery,
Externí odkaz:
https://doaj.org/article/70ea25fc008b413291803f7ea6e74b35
Autor:
Lin, Hsin-Yun, Mohammadhosseini, Mona, McClatchy, John, Villamor-Payà, Marina, Jeng, Sophia, Bottomly, Daniel, Tsai, Chia-Feng, Posso, Camilo, Jacobson, Jeremy, Adey, Andrew, Gosline, Sara, Liu, Tao, McWeeney, Shannon, Stracker, Travis H., Agarwal, Anupriya
Publikováno v:
In Blood 27 June 2024 143(26):2749-2762
Autor:
Shannon McWeeney, Daniel Bottomly
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Immuno-oncology involves the study of approaches which harness the patient’s immune system to fight malignancies. Immuno-oncology, as with every other biomedical and clinical research field as well as clinical operations, is in the midst of technol
Externí odkaz:
https://doaj.org/article/56bcb34e6881472b91aa59c9c278be1d
Akademický článek
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Autor:
Myles Vigoda, Chase Mathieson, Nathaniel Evans, Carolyn Hale, Jennifer Jennings, Olivia Lucero, Sophia Jeng, Daniel Bottomly, Daniel Clayburgh, Peter Andersen, Ryan Li, Daniel Petrisor, Jeffrey W. Tyner, Shannon McWeeney, Molly Kulesz-Martin
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 309-317 (2022)
In this study, we report a differential response of mitogen-activated protein kinase–kinase (MEK) inhibitor trametinib in 20 head and neck squamous cell carcinoma (HNSCC) patients’ tumor-derived cell cultures. Relatively sensitive and resistant c
Externí odkaz:
https://doaj.org/article/b341787595d24a049de4dd01f9d67b72
Autor:
Lachowiez, Curtis A. ∗, Long, Nicola, Saultz, Jennifer, Gandhi, Arpita, Newell, Laura F., Hayes-Lattin, Brandon, Maziarz, Richard T., Leonard, Jessica, Bottomly, Daniel, McWeeney, Shannon, Dunlap, Jennifer, Press, Richard, Meyers, Gabrielle, Swords, Ronan, Cook, Rachel J., Tyner, Jeffrey W., Druker, Brian J., Traer, Elie
Publikováno v:
In Blood Advances 9 May 2023 7(9):1899-1909
Akademický článek
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Autor:
Kyle A. Romine, Daniel Bottomly, William Yashar, Nicola Long, Matthew Viehdorfer, Shannon K. McWeeney, Jeffrey W. Tyner
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionThe implementation of small-molecule and immunotherapies in acute myeloid leukemia (AML) has been challenging due to genetic and epigenetic variability amongst patients. There are many potential mechanisms by which immune cells could infl
Externí odkaz:
https://doaj.org/article/9251dcb7a94c4cb194fdc06f503f7fdd
Autor:
Elana Thieme, Tingting Liu, Nur Bruss, Carly Roleder, Vi Lam, Xiaoguang Wang, Tamilla Nechiporuk, Geoffrey Shouse, Olga V. Danilova, Daniel Bottomly, Shannon K. McWeeney, Jeffrey W. Tyner, Stephen E. Kurtz, Alexey V. Danilov
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-11 (2022)
Abstract Aberrant B-cell receptor (BCR) signaling is a key driver in lymphoid malignancies. Bruton tyrosine kinase (BTK) inhibitors that disrupt BCR signaling have received regulatory approvals in therapy of mantle cell lymphoma (MCL). However, respo
Externí odkaz:
https://doaj.org/article/6ba6538ef93547b086ba5fe9d9f53329
Autor:
Kurtz, Stephen E. *, Eide, Christopher A. *, Kaempf, Andy, Long, Nicola, Bottomly, Daniel, Nikolova, Olga, Druker, Brian J., McWeeney, Shannon K., Chang, Bill H., Tyner, Jeffrey W. *, Agarwal, Anupriya *, *
Publikováno v:
In Blood Advances 24 May 2022 6(10):3062-3067