Zobrazeno 1 - 10
of 284
pro vyhledávání: '"A Benedict, Cosimi"'
Autor:
Abbas Dehnadi, A. Benedict Cosimi, Rex Neal Smith, Xiangen Li, José L. Alonso, Terry K. Means, M. Amin Arnaout
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Acute kidney injury can progress to chronic kidney disease. Here Dehnadiet al. develop a post-ischaemic chronic kidney disease model in cynomolgus monkeys and show that prophylactic inhibition of CD11b/CD18 leukocyte receptor via a monoclonal antibod
Externí odkaz:
https://doaj.org/article/d0055b59431d4c87ad00b0f269919925
Autor:
Hajime Sasaki, Takayuki Hirose, Tetsu Oura, Ryo Otsuka, Ivy Rosales, David Ma, Grace Lassiter, Ahmad Karadagi, Toshihide Tomosugi, Abbas Dehnadi, Masatoshi Matsunami, Susan Raju Paul, Patrick M. Reeves, Isabel Hanekamp, Samuel Schwartz, Robert B. Colvin, Hang Lee, Thomas R. Spitzer, A. Benedict Cosimi, Pietro E. Cippà, Thomas Fehr, Tatsuo Kawai
Publikováno v:
Science Translational Medicine. 15
Hematopoietic stem cell transplantation (HSCT) has many potential applications beyond current standard indications, including treatment of autoimmune disease, gene therapy, and transplant tolerance induction. However, severe myelosuppression and othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f55bd7c79739e990779b0451a5dbd7a7
https://doi.org/10.1126/scitranslmed.add5318
https://doi.org/10.1126/scitranslmed.add5318
Autor:
Ivy A. Rosales, Grace K. Mahowald, Kristen Tomaszewski, Kiyohiko Hotta, Naoya Iwahara, Takuya Otsuka, Takahiro Tsuji, Yusuke Takada, Ellen Acheampong, Milagros Araujo-Medina, Amy Bruce, Andrea Rios, Anthony Benedict Cosimi, Nahel Elias, Tatsuo Kawai, Hannah Gilligan, Kassem Safa, Leonardo V. Riella, Nina E. Tolkoff-Rubin, Winfred W. Williams, Rex Neal Smith, Robert B. Colvin
Publikováno v:
Journal of the American Society of Nephrology : JASN. 33(12)
To seek insights into the pathogenesis of chronic active antibody-mediated rejection (CAMR), we performed mRNA analysis and correlated transcripts with pathologic component scores and graft outcomes.We utilized the NanoString nCounter platform and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e808dede5f3ffe4b9e374ae8543c69e7
https://pubmed.ncbi.nlm.nih.gov/36450597
https://pubmed.ncbi.nlm.nih.gov/36450597
Autor:
Hang Lee, Michael Mengel, Masatoshi Matsunami, Robert B. Colvin, Ivy A. Rosales, T. Oura, Benjamin Adam, Tatsuo Kawai, A. Benedict Cosimi, Rex Neal Smith
Publikováno v:
Transplantation
BACKGROUND Renal allograft tolerance (TOL) has been successfully induced in nonhuman primates (NHPs) and humans through the induction of transient mixed chimerism. To elucidate the mechanisms of TOL, we compared local immunologic responses in renal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f21a7e23270c7737f89535ba7798d39
https://doi.org/10.1097/tp.0000000000002911
https://doi.org/10.1097/tp.0000000000002911
Autor:
Eliot Heher, Shuli Li, Bimalangshu R. Dey, David H. Sachs, Nina Tolkoff-Rubin, Nahel Elias, Winfred W. Williams, Jay A. Fishman, Zachariah DeFilipp, Areej El-Jawahri, A. Benedict Cosimi, Tatsuo Kawai, Paul O'Donnell, Candice Del Rio, Kerry Collier, Yi Bin Chen, Thomas R. Spitzer, Steven L. McAfee, Jeannine S. McCune
Publikováno v:
Blood
At Massachusetts General Hospital, we pioneered simultaneous hematopoietic cell (HCT)/kidney transplantation from HLA-identical related donors for the treatment of hematological malignancies with end-stage renal failure. We have now extended this to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881e9cc2fbe84a803fff8a950a8010e7
https://doi.org/10.1182/blood.2019000775
https://doi.org/10.1182/blood.2019000775
Autor:
John D. Scandling, Nancy L. Ascher, Joshua Miller, Samuel Strober, Matthew R. Weir, Minnie M. Sarwal, A. Benedict Cosimi, David H. Sachs, Robert A. Montgomery, Anthony P. Monaco, Joren C. Madsen, Alberto Sanchez-Fueyo, Jean C. Emond, Kenneth A. Newell, Dixon B. Kaufman, Satoru Todo
Publikováno v:
Transplantation. 105(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df939f252e2e8385856426cd9ca3a3b
https://pubmed.ncbi.nlm.nih.gov/33901128
https://pubmed.ncbi.nlm.nih.gov/33901128
Autor:
Robert B. Colvin, Ivy A. Rosales, A. Dehnadi, Rex Neal Smith, A. Benedict Cosimi, Tatsuo Kawai, Svjetlan Boskovic, Kiyohiko Hotta, T. Oura, Masatoshi Matsunami
Publikováno v:
Transplantation. 102:e128-e136
Background We have previously reported successful induction of renal allograft tolerance in nonhuman primates (NHP) after an initial posttransplant period of conventional immunosuppression (delayed tolerance) using a nonmyeloablative conditioning reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54217f2cf0e4e9840ea1bbc176f1d24
https://doi.org/10.1097/tp.0000000000002078
https://doi.org/10.1097/tp.0000000000002078
Autor:
David H. Sachs, Megan Sykes, A. Benedict Cosimi, Francis L. Delmonico, Bimalangshu R. Dey, Tatsuo Kawai, Nina Tolkoff-Rubin, Yi-Bin Chen, Steven L. McAfee, Thomas R. Spitzer
Publikováno v:
Transplantation
Specific immune tolerance of transplanted organs in association with either transient or sustained lymphohematopoietic chimerism has been demonstrated in several preclinical animal models and clinically in patients who are full donor chimeras after h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b4971d78dbb2269c44b37313f0c7f3
https://pubmed.ncbi.nlm.nih.gov/30801529
https://pubmed.ncbi.nlm.nih.gov/30801529
Autor:
Hajime Sasaki, David D.F. Ma, A. Dehnadi, Takayuki Hirose, Benedict Cosimi, Tetsu Oura, Robert B. Colvin, Tatsuo Kawai, Ivy A. Rosales
Publikováno v:
Transplantation. 104:S156-S156
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7bcb402a6dc2ccba3f074fa77505559
https://doi.org/10.1097/01.tp.0000699112.45264.e0
https://doi.org/10.1097/01.tp.0000699112.45264.e0
Autor:
Kent Kawai, T. Oura, A. Benedict Cosimi, Hang Lee, Ivy A. Rosales, Kiyohiko Hotta, A. Dehnadi, Tatsuo Kawai
Publikováno v:
Transplantation. 103(1)
BACKGROUND: We recently reported anti-CD40 monoclonal antibody and rapamycin (aCD40/rapa) to be a reliable, nontoxic, immunosuppressive regimen for combined islet and kidney transplantation (CIKTx) in nonhuman primates (NHPs). In the current study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20dab1ed2e9050e6f00342768b9f3635
https://pubmed.ncbi.nlm.nih.gov/30113995
https://pubmed.ncbi.nlm.nih.gov/30113995