Zobrazeno 1 - 10
of 184
pro vyhledávání: '"A Belén Elgoyhen"'
Autor:
Julian Taranda, Stéphane F Maison, Jimena A Ballestero, Eleonora Katz, Jessica Savino, Douglas E Vetter, Jim Boulter, M Charles Liberman, Paul A Fuchs, A Belén Elgoyhen
Publikováno v:
PLoS Biology, Vol 7, Iss 1, p e18 (2009)
The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells. One fundamental question in auditory neuroscience is wha
Externí odkaz:
https://doaj.org/article/fe6e8caadb304db3972a5af73403bdc9
Autor:
Ana Belén Elgoyhen
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106735- (2023)
Within the superfamily of pentameric ligand-gated ion channels, cholinergic nicotinic receptors (nAChRs) were classically identified to mediate synaptic transmission in the nervous system and the neuromuscular junction. The α9 and α10 nAChR subunit
Externí odkaz:
https://doaj.org/article/d65033d59f744890b6554ab775e5cb6f
Autor:
Paula I Buonfiglio, Sebastián Menazzi, Liliana Francipane, Vanesa Lotersztein, Verónica Ferreiro, Ana Belén Elgoyhen, Viviana Dalamón
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0275703 (2023)
The present study investigates the spectrum and analysis of mitochondrial DNA (mtDNA) variants associated with Leber hereditary optic neuropathy (LHON) in an Argentinean cohort, analyzing 3 LHON-associated mitochondrial genes. In 32% of the cases, mo
Externí odkaz:
https://doaj.org/article/04b1d51d71b943c4994e8b5d73d874df
Autor:
Marcela Lipovsek, Ana Belén Elgoyhen
Publikováno v:
Trends in Neurosciences. 46:110-123
After the transition to life on land, tympanic middle ears emerged separately in different groups of tetrapods, facilitating the efficient detection of airborne sounds and paving the way for high frequency sensitivity. The processes that brought abou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba7aa7d99c03dcd61b98a0b82dab404
https://doi.org/10.1016/j.tins.2022.12.002
https://doi.org/10.1016/j.tins.2022.12.002
Autor:
Ana Belén Elgoyhen
Publikováno v:
Expert Opin Ther Targets
INTRODUCTION: Hearing loss is a major health problem, impacting education, communication, interpersonal relationships, and mental health. Drugs that prevent or restore hearing are lacking and hence novel drug targets are sought. There is the possibil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e6ac91414fa576a82a4a9e097fede1
https://pubmed.ncbi.nlm.nih.gov/35225139
https://pubmed.ncbi.nlm.nih.gov/35225139
Autor:
Daniela Chequer Charan, Yunfeng Hua, Haoyu Wang, Wenqing Huang, Fangfang Wang, Ana Belén Elgoyhen, Kevin M. Boergens, Mariano N. Di Guilmi
Publikováno v:
Frontiers in cellular neuroscience. 16
The medial nucleus of the trapezoid body (MNTB) is an integral component of the auditory brainstem circuitry involved in sound localization. The giant presynaptic nerve terminal with multiple active zones, the calyx of Held (CH), is a hallmark of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066f46d2efd660fa9231cc8fb7638dc9
https://pubmed.ncbi.nlm.nih.gov/36589288
https://pubmed.ncbi.nlm.nih.gov/36589288
Publikováno v:
The Journal of Neuroscience. 41:6812-6821
For normal cochlear function, outer hair cells (OHCs) require a precise control of intracellular Ca2+ levels. In the absence of regulatory elements such as proteinaceous buffers or extrusion pumps, OHCs degenerate, leading to profound hearing impairm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41f6148439303d462d9a165fab33806d
https://doi.org/10.1523/jneurosci.3008-20.2021
https://doi.org/10.1523/jneurosci.3008-20.2021
Autor:
Bruno Hernandez-Cravero, Sofia Gallino, Jeremy Florman, Cecilia Vranych, Philippe Diaz, Ana Belén Elgoyhen, Mark J. Alkema, Diego de Mendoza
The nematode Caenorhabditis elegans requires exogenous cholesterol to survive and its depletion leads to early development arrest. Thus, tight regulation of cholesterol storage and distribution within the organism is critical. Previously, we demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c305426606b7bfd893cb3253dbec917e
https://doi.org/10.1101/2022.07.20.500754
https://doi.org/10.1101/2022.07.20.500754
Autor:
Ana Belén Elgoyhen
Publikováno v:
Current Opinion in Physiology. 18:42-48
The auditory system is comprised of ascending and descending neuronal pathways. Corticofugal efferent projections are present at different relays of the auditory system. Of particular interest for this review are the olivocochlear fibers that project
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a6568c29d426128a01463ede20c57c
https://doi.org/10.1016/j.cophys.2020.07.020
https://doi.org/10.1016/j.cophys.2020.07.020
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