Zobrazeno 1 - 10
of 44
pro vyhledávání: '"A B Madhankumar"'
Autor:
A B Madhankumar, Oliver D Mrowczynski, Becky Slagle-Webb, Vagisha Ravi, Alexandre J Bourcier, Russell Payne, Kimberly S Harbaugh, Elias Rizk, James R Connor
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0181529 (2018)
Peripheral nerve sheath tumors are benign tumors that have the potential to transform into malignant peripheral nerve sheath tumors (MPNSTs). Interleukin-13 receptor alpha 2 (IL13Rα2) is a cancer associated receptor expressed in glioblastoma and oth
Externí odkaz:
https://doaj.org/article/3d581631ae1648e8b5e675d0ea7384cd
Autor:
Vagisha Ravi, Achuthamangalam B Madhankumar, Thomas Abraham, Becky Slagle-Webb, James R Connor
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221952 (2019)
Elevated expression of the iron regulatory protein, ferritin heavy chain 1 (FTH1), is increasingly being associated with high tumor grade and poor survival outcomes in glioblastoma. Glioma initiating cells (GICs), a small population of stem-like cell
Externí odkaz:
https://doaj.org/article/8ed939399d5e488e889c35212c2d1f6e
Publikováno v:
Materials Today: Proceedings. 45:751-756
Now-a-days, more concentration attention has been given for synthesizing of copper (Cu) nanoparticles due to its excellent physical and chemical properties. Different approaches are available to synthesize the Cu nanoparticles. Electrodeposition is a
Autor:
A. B. Madhankumar, James R. Connor, Hali Jiang, Cheng Dong, Xiaojun Lian, Joshua Reynolds, Jian Yang, Lauren N. Randolph, Gloria B. Kim, Virginia Aragon-Sanabria, Becky Webb
Publikováno v:
Bioactive Materials, Vol 5, Iss 3, Pp 624-635 (2020)
Bioactive Materials
Bioactive Materials
Glioblastoma (GBM), the deadliest form of brain cancer, presents long-standing problems due to its localization. Chimeric antigen receptor (CAR) T cell immunotherapy has emerged as a powerful strategy to treat cancer. IL-13-receptor-α2 (IL13Rα2), p
Autor:
James R. Connor, A. B. Madhankumar, Alexandre J. Bourcier, Christine Mau, Darren Wolfe, Elias Rizk, Oliver D. Mrowczynski, Kimberly Harbaugh, Becky Slagle-Webb, Stephan B. Abramson, Russell Payne, Ganesh Shenoy
Publikováno v:
Journal of Neurosurgery. 131:1369-1379
OBJECTIVEMalignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas that harbor a high potential for metastasis and have a devastating prognosis. Combination chemoradiation aids in tumor control and decreases tumor recurren
Autor:
Sheereen Majd, A. B. Madhankumar, James R. Connor, Claire K. Holley, Mohammad Reza Abidian, You Jung Kang
Publikováno v:
Advanced healthcare materials. 10(2)
The limited effectiveness of current therapeutics against malignant brain gliomas has led to an urgent need for development of new formulations against these tumors. Chelator Dp44mT (di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone) presents a pro
Autor:
Oliver D. Mrowczynski, James R. Connor, Elias Rizk, Yuanjun Zhao, Russell Payne, Becky Slagle-Webb, Jeffrey M. Sundstrom, Yuka Imamura Kawasawa, A. B. Madhankumar, Brad E. Zacharia, Christine Mau
Publikováno v:
Oncotarget
Radiation is utilized in the therapy of more than 50% of cancer patients. Unfortunately, many malignancies become resistant to radiation over time. We investigated the hypothesis that one method of a cancer cell's ability to survive radiation occurs
Publikováno v:
Neuro-Oncology. 23:vi18-vi18
Glioblastoma (GBM) is both the most common and deadly malignant primary brain tumor with a 1-year survival of 37.2% and a 5-year survival of just 5.1%. Despite advances in imaging technology, distinguishing between pseudoprogression and pseudorespons
Autor:
James R. Connor, A. B. Madhankumar, Michael Glantz, Li Chong Xu, Cody Weston, Brad E. Zacharia, Christopher A. Siedlecki, Suhag R. Patel, Oliver D. Mrowczynski
Publikováno v:
Acta Biomaterialia. 58:205-213
Cadmium selenide (CdSe) based quantum dots modified with polyethylene glycol and chemically linked to interleukin-13 (IL13) were prepared with the aim of identifying the high affinity receptor (IL13Rα2) which is expressed in glioma stem cells and ex
Autor:
James R. Connor, A. B. Madhankumar, Becky Slagle-Webb, Oliver D. Mrowczynski, Sang Y. Lee, Brad E. Zacharia
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1861:1921-1928
Neuroblastoma is the third most common childhood cancer, and timely diagnosis and sensitive therapeutic monitoring remain major challenges. Tumor progression and recurrence is common with little understanding of mechanisms. A major recent focus in ca