Zobrazeno 1 - 10
of 40
pro vyhledávání: '"A B Jamaluddin"'
Autor:
M. Fairuz B. Jamaluddin, Prathima B. Nagendra, Yi-An Ko, Preety Bajwa, Rodney J. Scott, Pravin Nahar, Pradeep S. Tanwar
Publikováno v:
Frontiers in Reproductive Health, Vol 5 (2023)
Uterine fibroids are exceedingly common benign tumours of the female reproductive system and cause severe symptoms, including acute pain, bleeding, and infertility. Fibroids are frequently associated with genetic alterations affecting mediator comple
Externí odkaz:
https://doaj.org/article/a97e6b190ff245989b9a6109c728a6c7
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Testicular cancer is a common malignancy of young males and is believed to be originated from defective embryonic or adult germ cells. Liver kinase B1 (LKB1) is a serine/threonine kinase and a tumor suppressor gene. LKB1 is a negative regulator of th
Externí odkaz:
https://doaj.org/article/6277bb468e884ed7b3da51c1bb90afcf
Autor:
Yu Chen Feng, Xiao Ying Liu, Liu Teng, Qiang Ji, Yongyan Wu, Jin Ming Li, Wei Gao, Yuan Yuan Zhang, Ting La, Hessam Tabatabaee, Xu Guang Yan, M. Fairuz B. Jamaluddin, Didi Zhang, Su Tang Guo, Rodney J. Scott, Tao Liu, Rick F. Thorne, Xu Dong Zhang, Lei Jin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
c-Myc and p53 operate in a negative feedback manner to maintain cellular homeostasis. Here, the authors report a long noncoding RNA, MILIP as a downstream target of c-Myc and that MILIP represses p53 to support tumorigenicity.
Externí odkaz:
https://doaj.org/article/3225348bd84d4f1584b3eda3c5bdafbd
Autor:
Aysha Ferdoushi, Xiang Li, Nathan Griffin, Sam Faulkner, M. Fairuz B. Jamaluddin, Fangfang Gao, Chen Chen Jiang, Dirk F. van Helden, Pradeep S. Tanwar, Phillip Jobling, Hubert Hondermarck
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Schwann cells (SCs), the glial component of peripheral nerves, have been identified as promoters of pancreatic cancer (PC) progression, but the molecular mechanisms are unclear. In the present study, we aimed to identify proteins released by SCs that
Externí odkaz:
https://doaj.org/article/30132879c8494f26b73f9fe2ec5dc843
Autor:
Ayesha Ali, Shafiq M. Syed, M. Fairuz B. Jamaluddin, Yolanda Colino-Sanguino, David Gallego-Ortega, Pradeep S. Tanwar
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1463-1477.e7 (2020)
Summary: The intact vaginal epithelium is essential for women’s reproductive health and provides protection against HIV and sexually transmitted infections. How this epithelium maintains itself remains poorly understood. Here, we used single-cell R
Externí odkaz:
https://doaj.org/article/4b3a2d42e98449e580d3f9f9883464ae
Autor:
Olivia Ruhen, Xinyu Qu, M. Fairuz B. Jamaluddin, Carlos Salomon, Aesha Gandhi, Michael Millward, Brett Nixon, Matthew D. Dun, Katie Meehan
Publikováno v:
Membranes, Vol 11, Iss 11, p 880 (2021)
Breast cancer is the leading cause of cancer death in women. The majority of these deaths are due to disease metastasis, in which cancer cells disseminate to multiple organs and disrupt vital physiological functions. It is widely accepted that breast
Externí odkaz:
https://doaj.org/article/596bb57a6da146349d6ad70a9bc8c080
Autor:
M. Fairuz B. Jamaluddin, Arnab Ghosh, Aviraj Ingle, Riazuddin Mohammed, Ayesha Ali, Mohammad Bahrami, Gerard Kaiko, Zamira Gibb, Elysse C. Filipe, Thomas R. Cox, Angela Boulton, Rachel O’Sullivan, Yvette Ius, Ajay Karakoti, Ajayan Vinu, Pravin Nahar, Kenneth Jaaback, Vipul Bansal, Pradeep S. Tanwar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(44)
Organoid technology has provided unique insights into human organ development, function, and diseases. Patient-derived organoids are increasingly used for drug screening, modeling rare disorders, designing regenerative therapies, and understanding di
Autor:
Ryan J. Duchatel, Evangeline R. Jackson, Sarah G. Parackal, Claire Sun, Paul Daniel, Abdul Mannan, Izac J. Findlay, Dilana Staudt, Zacary P. Germon, Sandra Laternser, Dylan Kiltschewskij, Padraic S. Kearney, M. Fairuz, B. Jamaluddin, Alicia M. Douglas, Tyrone Beitaki, Mika Persson, Elizabeth E. Manning, Heather C. Murray, Nicole M. Verrills, David A. Skerrett-Byrne, Brett Nixon, Susan Hua, Valdes-Mora Fatima, Maria Tsoli, David S. Ziegler, Murray J. Cairns, Eric Raabe, Nicholas A. Vitanza, Carl Koschmann, Frank Alvaro, Christopher V. Dayas, Christopher L. Tinkle, David D. Eisenstat, Ron Firestein, Sabine Mueller, Javad Nazarian, Jason E. Cain, Matthew D. Dun
Diffuse midline glioma (DMG), including tumors diagnosed in the brainstem (diffuse intrinsic pontine glioma – DIPG), are uniformly fatal brain tumors that lack effective pharmacological treatment. Analysis of pooled CRISPR-Cas9 loss-of-function gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7761ac079918d3d90d3ed9557966419d
https://doi.org/10.1101/2023.04.17.537256
https://doi.org/10.1101/2023.04.17.537256
Autor:
Dilana E. Staudt, Heather C. Murray, David A. Skerrett-Byrne, Nathan D. Smith, M. Fairuz B. Jamaluddin, Richard G. S. Kahl, Ryan J. Duchatel, Zacary P. Germon, Tabitha McLachlan, Evangeline R. Jackson, Izac J. Findlay, Padraic S. Kearney, Abdul Mannan, Holly P. McEwen, Alicia M. Douglas, Brett Nixon, Nicole M. Verrills, Matthew D. Dun
Publikováno v:
Clinical Proteomics. 20
Publikováno v:
Journal of lower genital tract disease.
The histopathologic diagnostic criteria of differentiated vulvar intraepithelial neoplasia (dVIN), the precursor of human papillomavirus-independent squamous cell carcinoma, are basal atypia, a negative or non-block-positive p16, and a supportive p53