Zobrazeno 1 - 10
of 159
pro vyhledávání: '"A B DeLeo"'
Autor:
Yufeng Wang, David L. Drum, Ruochuan Sun, Yida Zhang, Feng Chen, Fengfei Sun, Emre Dal, Ling Yu, Jingyu Jia, Shahrzad Arya, Lin Jia, Song Fan, Steven J. Isakoff, Allison M. Kehlmann, Gianpietro Dotti, Fubao Liu, Hui Zheng, Cristina R. Ferrone, Alphonse G. Taghian, Albert B. DeLeo, Marco Ventin, Giulia Cattaneo, Yongxiang Li, Youssef Jounaidi, Peigen Huang, Cristina Maccalli, Hanyu Zhang, Cheng Wang, Jibing Yang, Genevieve M. Boland, Ruslan I. Sadreyev, LaiPing Wong, Soldano Ferrone, Xinhui Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The poor efficacy of chimeric antigen receptor T-cell therapy (CAR T) for solid tumors is due to insufficient CAR T cell tumor infiltration, in vivo expansion, persistence, and effector function, as well as exhaustion, intrinsic target antig
Externí odkaz:
https://doaj.org/article/cdd6a0e581e24892b09297cc99e43a32
Autor:
Gong Zhang, Yufeng Wang, Bryan C. Fuchs, Wei Guo, David L. Drum, Derek J. Erstad, Baomin Shi, Albert B. DeLeo, Hui Zheng, Lei Cai, Liyuan Zhang, Kenneth K. Tanabe, Xinhui Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundSorafenib, a kinase inhibitor, is a standard treatment for advanced hepatocellular carcinoma (HCC) but provides only a limited survival benefit. Disulfiram (DSF), a drug for treating alcoholism and a chelator of copper (Cu), forms a complex
Externí odkaz:
https://doaj.org/article/edfdbb08ad7d4e848639da985e479712
Autor:
Ting Sun, Wei Yang, Sneh M. Toprani, Wei Guo, Lile He, Albert B. DeLeo, Soldano Ferrone, Gong Zhang, Enwen Wang, Zunwen Lin, Pan Hu, Xinhui Wang
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background The current successful clinical use of agents promoting robust anti-tumor immunity in cancer patients warrants noting that radiation therapy (RT) induces immunogenic cell death (ICD) of tumor cells, which can generate anti-tumor i
Externí odkaz:
https://doaj.org/article/aa6db65e6fa94485b6ba2a5b8b7affce
Autor:
Andreas E. Albers, Xu Qian, Andreas M. Kaufmann, Daphne Mytilineos, Robert L. Ferris, Thomas K. Hoffmann, Albert B. DeLeo
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract CD8+ cytotoxic T-cell (CTL) specific for non-mutated, wild type (wt) sequence p53 peptides derived from wt or mutant p53 molecules expressed in head and neck squamous cell carcinomas (HNSCC) have been detected in the circulation of patients
Externí odkaz:
https://doaj.org/article/8af6746c901d4c1baf196728163aa429
Autor:
Nikola L. Vujanovic, Yan Lin, Robert L. Ferris, Fernando Concha-Benavente, Albert B. DeLeo, Lazar Vujanovic, Andrea Sobo-Vujanovic
Gating strategy for STAT3 single-color flow cytometry analysis of splenic monocytes and granulocytes. Splenocytes were fixed, permeabilized, stained with IgG control or anti-pSTAT3 antibodies, and gated similarly as shown in Suppl. Fig. 1, Gate 2: Ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5a32abd08f5a905a661ca38947f8b3
https://doi.org/10.1158/2326-6066.22537244.v1
https://doi.org/10.1158/2326-6066.22537244.v1
Autor:
Nikola L. Vujanovic, Yan Lin, Robert L. Ferris, Fernando Concha-Benavente, Albert B. DeLeo, Lazar Vujanovic, Andrea Sobo-Vujanovic
MCA and TNF-exclusion don't affect Tregs. Splenocytes were simultaneously stained with anti-CD4-FITC and anti-CD25-PE mAb, fixed, permeabilized, stained with anti-FoxP3-APC mAb, and examined by flow cytometry. (A) Gating strategies: Gate 1, single ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586282ea183999a66ffaa00125a213d2
https://doi.org/10.1158/2326-6066.22537247.v1
https://doi.org/10.1158/2326-6066.22537247.v1
Autor:
Nikola L. Vujanovic, Yan Lin, Robert L. Ferris, Fernando Concha-Benavente, Albert B. DeLeo, Lazar Vujanovic, Andrea Sobo-Vujanovic
MCA doesn't affect while sTNF exclusion decreases frequency of macrophages. Experimental groups were set up as described in Fig. 3 legend. Splenocytes were simultaneously stained with anti-CD45R-FITC and anti-F4/80-PE antibodies, and examined by two-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c456f0308435eb2dd35d8418c3839dd
https://doi.org/10.1158/2326-6066.22537250.v1
https://doi.org/10.1158/2326-6066.22537250.v1
Autor:
Nikola L. Vujanovic, Yan Lin, Robert L. Ferris, Fernando Concha-Benavente, Albert B. DeLeo, Lazar Vujanovic, Andrea Sobo-Vujanovic
TNF is a potent promoter of carcinogenesis and potentially important target for cancer prevention. TNF is produced as functionally distinct transmembrane and soluble molecules (tmTNF and sTNF, respectively), but their individual roles in carcinogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9afc8e180e12bf2d35cbb6369ce8ecf0
https://doi.org/10.1158/2326-6066.c.6548363.v1
https://doi.org/10.1158/2326-6066.c.6548363.v1
Autor:
Nikola L. Vujanovic, Yan Lin, Robert L. Ferris, Fernando Concha-Benavente, Albert B. DeLeo, Lazar Vujanovic, Andrea Sobo-Vujanovic
Gating strategy for three-color flow cytometry analysis of splenic MDSCs. Splenocytes were simultaneously stained with anti-CD11b-FITC, anti-Gr1-PE and anti-Ly6C-APC antibodies or the corresponding isotype control antibodies and analyzed by flow cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936c0c80993b9c1a755a5d8b51dcbf55
https://doi.org/10.1158/2326-6066.22537253
https://doi.org/10.1158/2326-6066.22537253
Autor:
Wenhao Yao, Xu Qian, Sebastian Ochsenreither, Ferrone Soldano, Albert B. DeLeo, Holger Sudhoff, Felix Oppel, Andreas Kuppig, Konrad Klinghammer, Andreas M. Kaufmann, Andreas E. Albers
Publikováno v:
Cells, Vol 10, Iss 3, p 517 (2021)
The poor prognosis of locally advanced and metastatic head and neck squamous cell carcinoma (HNSCC) is primarily mediated by the functional properties of cancer stem cells (CSCs) and resistance to chemoradiotherapy. We investigated whether the aldehy
Externí odkaz:
https://doaj.org/article/0aa55da189de445cb228acb189e174b9