Zobrazeno 1 - 10
of 711
pro vyhledávání: '"A B Clifford"'
Autor:
Patricia K. Riggs, Albert M. Anderson, Bin Tang, Leah H. Rubin, Susan Morgello, Christina M. Marra, Benjamin B. Gelman, David B. Clifford, Donald Franklin, Robert K. Heaton, Ronald J. Ellis, Christine Fennema-Notestine, Scott L. Letendre
Publikováno v:
Viruses, Vol 15, Iss 12, p 2410 (2023)
Structural brain abnormalities, including those in white matter (WM), remain common in people with HIV (PWH). Their pathogenesis is uncertain and may reflect multiple etiologies. Oxidative stress is associated with inflammation, HIV, and its comorbid
Externí odkaz:
https://doaj.org/article/674144d9abd54ab9bbe9c396f0f14767
Autor:
Umesh G Lalloo, Lauren Komarow, Judith A Aberg, David B Clifford, Evelyn Hogg, Ashley McKhann, Aggrey Bukuru, David Lagat, Sandy Pillay, Vidya Mave, Khuanchai Supparatpinyo, Wadzanai Samaneka, Deborah Langat, Eduardo Ticona, Sharlaa Badal-Faesen, Robert A Larsen, ACTG A5225 Team
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281580 (2023)
BackgroundThe WHO recommended 1200mg/day of fluconazole (FCZ) in the induction phase of cryptococcal meningitis (CM) in HIV prior to 2018 in regions where amphotericin-B (AMB) was unavailable. A 2-stage AMB-controlled, dose-escalation study to determ
Externí odkaz:
https://doaj.org/article/d5c2b08341f74d62a664c9a9098c7601
Autor:
Azin Tavasoli, Benjamin B. Gelman, Christina M. Marra, David B. Clifford, Jennifer E. Iudicello, Leah H. Rubin, Scott L. Letendre, Bin Tang, Ronald J. Ellis
Publikováno v:
Viruses, Vol 15, Iss 9, p 1835 (2023)
Background: HIV infection causes neuroinflammation and immune activation (NIIA) and systemic inflammation and immune activation (SIIA), which in turn drive neurodegeneration (ND). Cross-sectionally, higher levels of NIIA biomarkers correlate with inc
Externí odkaz:
https://doaj.org/article/b42708e8f81d4d1a875864ea25efcc6b
Autor:
Andrew J. Aschenbrenner, Jason Hassenstab, Guoqiao Wang, Yan Li, Chengjie Xiong, Eric McDade, David B. Clifford, Stephen Salloway, Martin Farlow, Roy Yaari, Eden Y. J. Cheng, Karen C. Holdridge, Catherine J. Mummery, Colin L. Masters, Ging-Yuek Hsiung, Ghulam Surti, Gregory S. Day, Sandra Weintraub, Lawrence S. Honig, James E. Galvin, John M. Ringman, William S. Brooks, Nick C. Fox, Peter J. Snyder, Kazushi Suzuki, Hiroyuki Shimada, Susanne Gräber, Randall J. Bateman
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Demonstrating a slowing in the rate of cognitive decline is a common outcome measure in clinical trials in Alzheimer’s disease (AD). Selection of cognitive endpoints typically includes modeling candidate outcome measures in the many, richly phenoty
Externí odkaz:
https://doaj.org/article/729c320574be4f4a868a3bad97db96d9
Autor:
Ronald J. Ellis, Robert K. Heaton, Bin Tang, A.C. Collier, Christina M. Marra, Benjamin B. Gelman, S. Morgello, David B. Clifford, N. Sacktor, D. Cookson, Scott Letendre
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 21, Iss , Pp 100437- (2022)
Background: Neurocognitive (NC) impairment in people with HIV (PWH) is associated with important adverse outcomes, but no markers exist to predict long-term NC decline. We evaluated depressed mood and markers of persistent inflammation, oxidative str
Externí odkaz:
https://doaj.org/article/8fab74bc552e4ff1a731841bdaaa2ff7
Autor:
Ronald J. Ellis, Monica Diaz, Ned Sacktor, Christina Marra, Ann C. Collier, David B. Clifford, Nigel Calcutt, Jerel A. Fields, Robert K. Heaton, Scott L. Letendre, for the CNS Antiretroviral Therapy Effects Research (CHARTER) Study Group
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 7, Pp 1166-1173 (2020)
Abstract Objective Distal sensory polyneuropathy (DSP) and neuropathic pain are important clinical concerns in virally suppressed people with HIV. We determined how these conditions evolved, what factors influenced their evolution, and their clinical
Externí odkaz:
https://doaj.org/article/9cb1cb04db55467e948211f52ff738fd
Autor:
Chioma U. Odozor, Kristen Roles, Carrie Burk, Thomas Kannampallil, David B. Clifford, Jay F. Piccirillo, Simon Haroutounian
Publikováno v:
PAIN Reports, Vol 6, Iss 1, p e925 (2021)
Abstract. Introduction and Objectives:. The coronavirus disease 2019 (COVID-19) pandemic has resulted in patients experiencing symptoms that include neurological dysfunction. As many viral infections are associated with neuropathy, the aim of the stu
Externí odkaz:
https://doaj.org/article/d98e67d5a9044baeb35c837944759fd1
Autor:
M. Lang, A. Tabari, D. Polak, J. Ford, B. Clifford, W.-C. Lo, K. Manzoor, D.N. Splitthoff, L.L. Wald, O. Rapalino, P. Schaefer, J. Conklin, S. Cauley, S.Y. Huang
Publikováno v:
American Journal of Neuroradiology. 44:125-133
Autor:
Asha R Kallianpur, Wanqing Wen, Angelika L Erwin, David B Clifford, Todd Hulgan, Gregory K Robbins
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239758 (2020)
ObjectivePeople with HIV (PWH) continue to experience sensory neuropathy and neuropathic pain in the combination antiretroviral therapy (cART) era for unclear reasons. This study evaluated the role of iron in a previously reported association of iron
Externí odkaz:
https://doaj.org/article/2f8df3fb19de4cf7b872797a0f86b2be
Twelve-year neurocognitive decline in HIV is associated with comorbidities, not age: a CHARTER study
Autor:
Robert K Heaton, Ronald J Ellis, Bin Tang, Christina M Marra, Leah H Rubin, David B Clifford, J Allen McCutchan, Benjamin B Gelman, Susan Morgello, Donald R Franklin, Scott L Letendre
Publikováno v:
Brain : a journal of neurology, vol 146, iss 3
Brain
Brain
Modern antiretroviral therapy (ART) has increased longevity of people with HIV and shifted the age distribution of the HIV pandemic upward toward that of the general population. This positive development has also led to concerns about premature and/o