Zobrazeno 1 - 10
of 31
pro vyhledávání: '"A B, Vermelho"'
Autor:
Andreza R. Garcia, Mariana M. B. Amorim, Ana Claudia F. Amaral, Jefferson D. da Cruz, Alane B. Vermelho, Dirlei Nico, Igor A. Rodrigues
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 8, Iss 7, p 375 (2023)
Human tegumentary leishmaniasis (HTL) is a serious tropical disease caused by Leishmania amazonensis. Developing new leishmanicidal agents can help overcome current treatment challenges, such as drug resistance and toxicity. Essential oils are a sour
Externí odkaz:
https://doaj.org/article/c4962e0d20d842239fc72def71fd7f0e
Autor:
Javier M. Anaya-Mancipe, Vanessa M. Queiroz, Rafael F. dos Santos, Rosane N. Castro, Verônica S. Cardoso, Alane B. Vermelho, Marcos L. Dias, Rossana M. S. M. Thiré
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1047 (2023)
Plantago major L. is a plant available worldwide that has been traditionally used for several medical applications due to its wound healing, anti-inflammatory, and antimicrobial properties. This work aimed to develop and evaluate a nanostructured PCL
Externí odkaz:
https://doaj.org/article/a9a0477f2d324e3e9cff4512afc3e6d5
Autor:
Alessio Nocentini, Sameh M. Osman, Igor A. Rodrigues, Veronica S. Cardoso, Fatmah Ali S. Alasmary, Zeid AlOthman, Alane B. Vermelho, Paola Gratteri, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1164-1171 (2019)
Chagas disease and leishmaniasis are neglected tropical disorders caused by the protozoans Trypanosoma cruzi and Leishmania spp. Carbonic anhydrases (CAs, EC 4.2.1.1) from these protozoans (α-TcCA and β-LdcCA) have been validated as promising targe
Externí odkaz:
https://doaj.org/article/1bbb9c4fabf9427fb1d0d648007f3e3d
Autor:
Andreza R. Garcia, Danielle M. P. Oliveira, Ana Claudia F. Amaral, Jéssica B. Jesus, Ana Carolina Rennó Sodero, Alessandra M. T. Souza, Claudiu T. Supuran, Alane B. Vermelho, Igor A. Rodrigues, Anderson S. Pinheiro
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1100-1109 (2019)
Inhibition of Leishmania arginase leads to a decrease in parasite growth and infectivity and thus represents an attractive therapeutic strategy. We evaluated the inhibitory potential of selected naturally occurring phenolic substances on Leishmania i
Externí odkaz:
https://doaj.org/article/bac4db29ff844b0db8ebca4f524359e4
Autor:
Andreza R. Garcia, Danielle M. P. Oliveira, Jessica B. Jesus, Alessandra M. T. Souza, Ana Carolina R. Sodero, Alane B. Vermelho, Ivana C. R. Leal, Rodrigo Octavio M. A. Souza, Leandro S. M. Miranda, Anderson S. Pinheiro, Igor A. Rodrigues
Publikováno v:
Frontiers in Chemistry, Vol 8 (2021)
Arginase catalyzes the hydrolysis of l-arginine into l-ornithine and urea, acting as a key enzyme in the biosynthesis of polyamines. Leishmania growth and survival is dependent on polyamine biosynthesis; therefore, inhibition of Leishmania arginase m
Externí odkaz:
https://doaj.org/article/ff088d1c74a24a95898a1f5b7c0c8a3c
Autor:
Andreza R. Garcia, Yasmin P. G. Silva-Luiz, Celuta S. Alviano, Daniela S. Alviano, Alane B. Vermelho, Igor A. Rodrigues
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 7, Iss 6, p 112 (2022)
Leishmaniasis is a vector-borne disease against which there are no approved vaccines, and the treatment is based on highly toxic drugs. The alkaloids consist of a chemical class of natural nitrogen-containing substances with a long history of antilei
Externí odkaz:
https://doaj.org/article/280099ed32674567835314ab0550a9a2
Autor:
Andreza R. Garcia, Ana Claudia F. Amaral, Mariana M. B. Azevedo, Suzana Corte-Real, Rosana C. Lopes, Celuta S. Alviano, Anderson S. Pinheiro, Alane B. Vermelho, Igor A. Rodrigues
Publikováno v:
Pharmaceutical Biology, Vol 55, Iss 1, Pp 1780-1786 (2017)
Context: Leishmania amazonensis is the main agent of diffuse cutaneous leishmaniasis, a disease characterized by lesional polymorphism and the commitment of skin surface. Previous reports demonstrated that the Citrus genus possess antimicrobial activ
Externí odkaz:
https://doaj.org/article/dc4e4acb69c442f0a53982e39f536520
Autor:
Andreza R. Garcia, Ana Claudia F. Amaral, Ana Clara B. Maria, Mariana M. Paz, Mariana M. B. Amorim, Francisco C. M. Chaves, Alane B. Vermelho, Dirlei Nico, Igor A. Rodrigues
Publikováno v:
Chemistrybiodiversity.
Leishmania amazonensis is the etiological agent of tegumentary leishmaniasis, a disease characterized by the emergence of cutaneous and mucocutaneous ulcerated lesions that can evolve into severe destruction of skin tissue. The disease treatment is o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2df0b64b18ac70bcd27cee1dc46836
https://pubmed.ncbi.nlm.nih.gov/36565272
https://pubmed.ncbi.nlm.nih.gov/36565272
Publikováno v:
3 Biotech
The poultry industry produces millions of tons of feathers waste that can be transformed into valuable products through bioprocess. The study describes the enhanced keratinase and feather hydrolysate production by Bacillus subtilis AMR. The metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b383621d2f5f120a0a4c47ef1db6ed0
https://doi.org/10.1007/s13205-022-03153-y
https://doi.org/10.1007/s13205-022-03153-y
Autor:
Igor A. Rodrigues, Ana Maria Mazotto, Verônica Cardoso, Renan L. Alves, Ana Claudia F. Amaral, Jefferson Rocha de Andrade Silva, Anderson S. Pinheiro, Alane B. Vermelho
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Leishmaniasis is a vector-borne disease that affects several populations worldwide, against which there are no vaccines available and the chemotherapy is highly toxic. Depending on the species causing the infection, the disease is characterized by co
Externí odkaz:
https://doaj.org/article/af3e9ac10fae42aaa2552abeecb876bd