Zobrazeno 1 - 10
of 42
pro vyhledávání: '"A B, Verkhovsky"'
Autor:
Antonina Y Alexandrova, Katya Arnold, Sébastien Schaub, Jury M Vasiliev, Jean-Jacques Meister, Alexander D Bershadsky, Alexander B Verkhovsky
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3234 (2008)
Dynamic actin network at the leading edge of the cell is linked to the extracellular matrix through focal adhesions (FAs), and at the same time it undergoes retrograde flow with different dynamics in two distinct zones: the lamellipodium (peripheral
Externí odkaz:
https://doaj.org/article/e49fc3e84bc24eb19cb071b92308b1c7
Traction Forces Control Cell-Edge Dynamics and Mediate Distance-Sensitivity During Cell Polarization
Publikováno v:
SSRN Electronic Journal.
SUMMARYTraction forces are generated by cellular actin-myosin system and transmitted to the environment through adhesions. They are believed to drive cell motion, shape changes, and extracellular matrix remodeling [1–3]. However, most of the tracti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46f38c127595fa26b8bfa43bfb69083
https://doi.org/10.2139/ssrn.3441418
https://doi.org/10.2139/ssrn.3441418
Traction Forces Control Cell-Edge Dynamics and Mediate Distance Sensitivity during Cell Polarization
Publikováno v:
Current Biology. 30:1762-1769.e5
Traction forces are generated by cellular actin-myosin system and transmitted to the environment through adhesions. They are believed to drive cell motion, shape changes, and extracellular matrix remodeling [1 -3] . However, most of the traction forc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a450d14adc34c21928d9caef390d7f0e
https://doi.org/10.1016/j.cub.2020.02.078
https://doi.org/10.1016/j.cub.2020.02.078
Autor:
Franck Raynaud, Mark E. Ambühl, Alicia Bornert, Chiara Gabella, Jean-Jacques Meister, Ivo F. Sbalzarini, Alexander B. Verkhovsky
Publikováno v:
Nature Physics
How the cells break symmetry and organize their edge activity to move directionally is a fun- damental question in cell biology. Physical models of cell motility commonly rely on gradients of regulatory factors and/or feedback from the motion itself
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f054b41297efcc298904fe22db8bcc61
http://arxiv.org/abs/1609.09006
http://arxiv.org/abs/1609.09006
Autor:
Benoît Vianay, Alexander B. Verkhovsky, Céline Labouesse, Chiara Gabella, Jean-Jacques Meister
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, ⟨10.1038/srep23722⟩
Scientific Reports (6), . (2016)
Scientific Reports, Nature Publishing Group, 2016, 6, ⟨10.1038/srep23722⟩
Scientific Reports (6), . (2016)
Actin-myosin filament bundles (stress fibers) are critical for tension generation and cell shape, but their mechanical properties are difficult to access. Here we propose a novel approach to probe individual peripheral stress fibers in living cells t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3828c1dc6fbf81da17ee79c5d95d91
Autor:
Jean-Jacques Meister, Alexander B. Verkhovsky, C. Brepsant, Mark E. Ambühl, Ivo F. Sbalzarini
Publikováno v:
Journal of Microscopy. 245:161-170
Accurate extraction of cell outlines from microscopy images is essential for analysing the dynamics of migrating cells. Phase-contrast microscopy is one of the most common and convenient imaging modalities for observing cell motility because it does
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db3911aa20712d6ca54fcc9f14db5d60
https://doi.org/10.1111/j.1365-2818.2011.03558.x
https://doi.org/10.1111/j.1365-2818.2011.03558.x
Autor:
Maxime F. Fournier, Alexander B. Verkhovsky, Davide Carlo Ambrosi, Jean-Jacques Meister, Roger Sauser
Publikováno v:
The Journal of Cell Biology
Analysis of the relationship between actin network velocity and traction forces at the substrate shows that force transmission mechanisms vary with distinct regions of the cell.
During cell migration, forces generated by the actin cytoskeleton a
During cell migration, forces generated by the actin cytoskeleton a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3779d35a3a416c3e3008b4419214cbef
https://doi.org/10.1083/jcb.200906139
https://doi.org/10.1083/jcb.200906139
Autor:
Saadi Khochbin, Christoph Ballestrem, Michael M. Kozlov, Tom Shemesh, Benoit Gilquin, Letizia Carramusa, Antonina Y. Alexandrova, Yuliya Zilberman, Alexander D. Bershadsky, Alexander B. Verkhovsky
Publikováno v:
European Journal of Cell Biology. 85:165-173
Initial integrin-mediated cell-matrix adhesions (focal complexes) appear underneath the lamellipodia, in the regions of the "fast" centripetal flow driven by actin polymerization. Once formed, these adhesions convert the flow behind them into a "slow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241538c48046158164a08a873c672877
https://doi.org/10.1016/j.ejcb.2005.11.001
https://doi.org/10.1016/j.ejcb.2005.11.001
Autor:
Jean-Jacques Meister, Gary G. Borisy, Sébastien Schaub, Oleg Y. Chaga, Alexander B. Verkhovsky, Tatyana Svitkina
Publikováno v:
Molecular Biology of the Cell. 14:4667-4675
Lamellipodia of crawling cells represent both the motor for cell advance and the primary building site for the actin cytoskeleton. The organization of actin in the lamellipodium reflects actin dynamics and is of critical importance for the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75f54077aef3f19289d094094745241
https://doi.org/10.1091/mbc.e02-10-0630
https://doi.org/10.1091/mbc.e02-10-0630
Autor:
Chiara Gabella, Jean-Jacques Meister, Alexander B. Verkhovsky, Benoît Vianay, Niccolò Piacentini
Publikováno v:
Lab on a chip. 14(14)
Actin-myosin microfilament bundles or stress-fibers are the principal tension-generating structures in the cell. Their mechanical properties are critical for cell shape, motion, and interaction with other cells and extracellular matrix, but were so f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6312fa70920775c1f52298cd7a101373
https://pubmed.ncbi.nlm.nih.gov/24867825
https://pubmed.ncbi.nlm.nih.gov/24867825