Zobrazeno 1 - 10
of 37
pro vyhledávání: '"A B, Troutt"'
Autor:
Mary A. Antonysamy, William C. Fanslow, Fumin Fu, Wei Li, Shiguang Qian, Anthony B. Troutt, Angus W. Thomson
Publikováno v:
The Journal of Immunology. 162:577-584
IL-17 is a T cell-derived cytokine that stimulates stromal cells and macrophages to secrete proinflammatory cytokines. We hypothesized that IL-17 might play a role in alloimmune responses, and that interference with its activity might suppress allogr
Publikováno v:
Cellular Immunology. 179:66-73
The daily administration of IL-15 to cyclophosphamide (CY)-injected mice bearing the 76-9 rhabdomyosarcoma was shown to prolong the period of remission induced by CY. In addition, IL-15 was shown to enhance the efficacy of adoptive immunotherapy. Cyt
Publikováno v:
American Journal of Reproductive Immunology. 37:262-266
PROBLEM In several models of abortion in rodents, the success or failure of the implanted embryos is determined by a balance between pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha), interleukin-2, interleukin-1 (IL-1), and
Publikováno v:
European Journal of Immunology. 25:1168-1175
The diversity of cytokine production patterns displayed by T cells activated in vivo was investigated by analyzing short-term antigen-specific CD4+ T cell clones and single CD4+ T cells derived from draining lymph nodes of mice undergoing a T helper
Autor:
Anthony B. Troutt, Mary A. Antonysamy, Vladimir M. Subbotin, Angus W. Thomson, Abdul S. Rao, J L Tang
Publikováno v:
Transplantation. 72:348-350
Background Blocking the action of interleukin (IL) 17 with an IL-17 receptor (R):Fc fusion protein inhibits T-cell proliferative responses to alloantigens and prolongs vascularized heart graft survival. In this study, we examined whether IL-17 antago
Publikováno v:
The Journal of Immunology. 149:2715-2721
Limiting dilution analysis was used to estimate the frequency of clonogenic Ag-specific CD4+ T lymphocytes in draining lymph nodes of mice over the course of infection with Leishmania major, and to measure the production of IL-2, IL-3, IL-4, IFN-gamm
Autor:
Anthony B. Troutt, Anne Kelso
Publikováno v:
Proceedings of the National Academy of Sciences. 89:5276-5280
A method of enumerating lymphokine mRNA-containing cells in vivo was developed by combining limiting dilution analysis with PCR amplification of cDNA. Single-hit kinetics revealed that the PCR-limiting dilution analysis could detect a single positive
Publikováno v:
International Immunology. 4:475-485
Interaction between the cell adhesion molecules lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1) augments T cell activation by increasing the avidity of T cell/antigen-presenting cell (APC) binding. To e
Autor:
Anne Kelso, Eugene Maraskovsky, Anthony B. Troutt, Nicholas M. Gough, Lynn Morris, Jennifer A. Thomson, Michael H. Pech
Publikováno v:
Immunological Reviews. 123:85-114
Analysis of lymphokine mRNA expression and protein secretion by about 100 short-term alloreactive T-cell clones revealed marked heterogeneity in the combinations of lymphokines synthesized. This finding argues against a simple model in which T cells
Publikováno v:
Transplantation. 72(2)
Blocking the action of interleukin (IL) 17 with an IL-17 receptor (R):Fc fusion protein inhibits T-cell proliferative responses to alloantigens and prolongs vascularized heart graft survival. In this study, we examined whether IL-17 antagonism could