Zobrazeno 1 - 10
of 250
pro vyhledávání: '"A B, Lentsch"'
Autor:
S. Whitney Zingg, Rebecca Schuster, Bernadin Joseph, Charles C. Caldwell, Alex B. Lentsch, Michael D. Goodman, Timothy A. Pritts
Publikováno v:
Surgery. 172:1829-1836
Current management of hemorrhagic shock relies on control of surgical bleeding along with resuscitation with packed red blood cells and plasma in a 1-to-1 ratio. Transfusion, however, is not without consequence as red blood cells develop a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd2ba9703314e397916305b68c6ae05
https://doi.org/10.1016/j.surg.2022.07.016
https://doi.org/10.1016/j.surg.2022.07.016
Autor:
Kasiemobi E. Pulliam, Bernadin Joseph, Amy T. Makley, Charles C. Caldwell, Alex B. Lentsch, Michael D. Goodman, Timothy A. Pritts
Publikováno v:
Surgery
Massive transfusion with older packed red blood cells is associated with increased morbidity and mortality. As packed red blood cells age, they undergo biochemical and structural changes known as the storage lesion. We developed a novel solution to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c2b3898f1ce79c4403cc4825d4b0b7
https://doi.org/10.1016/j.surg.2021.11.020
https://doi.org/10.1016/j.surg.2021.11.020
Autor:
Yael Pewzner‐Jung, Shaghayegh Tavakoli Tabazavareh, Heike Grassmé, Katrin Anne Becker, Lukasz Japtok, Jörg Steinmann, Tammar Joseph, Stephan Lang, Burkhard Tuemmler, Edward H Schuchman, Alex B Lentsch, Burkhard Kleuser, Michael J Edwards, Anthony H Futerman, Erich Gulbins
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 9, Pp 1205-1214 (2014)
Abstract Cystic fibrosis patients and patients with chronic obstructive pulmonary disease, trauma, burn wound, or patients requiring ventilation are susceptible to severe pulmonary infection by Pseudomonas aeruginosa. Physiological innate defense mec
Externí odkaz:
https://doaj.org/article/55d4097c03cf407d8211159fa40ab68e
Autor:
Hiroyuki Nojima, Takanori Konishi, Christopher M Freeman, Rebecca M Schuster, Lukasz Japtok, Burkhard Kleuser, Michael J Edwards, Erich Gulbins, Alex B Lentsch
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161443 (2016)
Exosomes are small membrane vesicles released by different cell types, including hepatocytes, that play important roles in intercellular communication. We have previously demonstrated that hepatocyte-derived exosomes contain the synthetic machinery t
Externí odkaz:
https://doaj.org/article/b60125bd7e694f3b907dcd8da3561393
Autor:
Alex B. Lentsch, Timothy A. Pritts, Rebecca Schuster, Brian Gavitt, Charles C. Caldwell, Andrew D. Jung, Lou Ann Friend, Sabre Stevens-Topie
Publikováno v:
Military Medicine. 185:e1528-e1535
Introduction Combined burn injury and hemorrhagic shock are a common cause of injury in wounded warfighters. Current protocols for resuscitation for isolated burn injury and isolated hemorrhagic shock are well defined, but the optimal strategy for co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3baf77884b726083c2294c0ae17b5dad
https://doi.org/10.1093/milmed/usz430
https://doi.org/10.1093/milmed/usz430
Autor:
Kasiemobi E Pulliam, Charles C. Caldwell, Rosalie A Veile, Amy T. Makley, Bernadin Joseph, Alex B. Lentsch, Michael D. Goodman, Lou Ann Friend, Timothy A. Pritts
Publikováno v:
J Trauma Acute Care Surg
BACKGROUND: Recent military and civilian experience suggests that fresh whole blood may be the preferred for treatment of hemorrhagic shock, but its use is limited by its 21-day shelf life. The red blood cell storage lesion and coagulation status of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2c3ba97210aabac13f608726104192
https://doi.org/10.1097/ta.0000000000002839
https://doi.org/10.1097/ta.0000000000002839
Autor:
Taylor A Johanningman, Alex B. Lentsch, Lou Ann Friend, Jeffrey M. Sutton, Richard S. Hoehn, Peter L. Jernigan, Charles C. Caldwell, Timothy A. Pritts, Nadine Beckmann, Rebecca Schuster
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Acute lung injury is a major complication of hemorrhagic shock and the required resuscitation with large volumes of crystalloid fluids and blood products. We previously identified a role of macrophage-derived chemokine (CCL22/MDC) pulmonary inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ceed5348fa2a6387b8f3769d26271e
https://doi.org/10.1152/ajplung.00455.2019
https://doi.org/10.1152/ajplung.00455.2019
Autor:
Timothy A. Pritts, Andrew D. Jung, Young Kim, William Abplanalp, Charles C. Caldwell, Alex B. Lentsch, Michael D. Goodman, Rebecca Schuster
Publikováno v:
Thromb Res
Introduction During storage, packed red blood cells undergo a series of physical, metabolic, and chemical changes collectively known as the red blood cell storage lesion. One key component of the red blood cell storage lesion is the accumulation of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef7e41701941b6fe08cb7553a36e37e
https://doi.org/10.1016/j.thromres.2019.11.028
https://doi.org/10.1016/j.thromres.2019.11.028
Autor:
Gregory C Wilson, Satoshi Kuboki, Christopher M Freeman, Hiroyuki Nojima, Rebecca M Schuster, Michael J Edwards, Alex B Lentsch
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120092 (2015)
Our previous in vitro studies have demonstrated dose-dependent effects of CXCR2 ligands on hepatocyte cell death and proliferation. In the current study, we sought to determine if CXCR2 ligand concentration is responsible for the divergent effects of
Externí odkaz:
https://doaj.org/article/2b03daf7698e4042a3657125aefd6b71
Autor:
Shunying Jin, Michael L Merchant, Jeffrey D Ritzenthaler, Kenneth R McLeish, Eleanor D Lederer, Edilson Torres-Gonzalez, Mostafa Fraig, Michelle T Barati, Alex B Lentsch, Jesse Roman, Jon B Klein, Madhavi J Rane
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121637 (2015)
Immune-complexes play an important role in the inflammatory diseases of the lung. Neutrophil activation mediates immune-complex (IC) deposition-induced acute lung injury (ALI). Components of gamma amino butyric acid (GABA) signaling, including GABA B
Externí odkaz:
https://doaj.org/article/241d62c110c54c75a52fcfa8b728e13c