Zobrazeno 1 - 10
of 155
pro vyhledávání: '"A B, Begovich"'
Autor:
Michael A. Panzara, Emanuela Gussoni, Ann B. Begovich, Ronald S. Murray, Ying Q. Zang, Stanley H. Appel, Lawrence Steinman, Jingwu Zhang
Publikováno v:
Neurobiology of Disease, Vol 6, Iss 5, Pp 392-405 (1999)
Amyotrophic lateral sclerosis (ALS) is a fatal disorder whose etiology and pathogenesis remain unknown. Recent studies, however, have demonstrated the presence of inflammatory infiltrates within ALS spinal cord and suggested the possibility of an imm
Externí odkaz:
https://doaj.org/article/707c9e2de62e42aaabf603e87d95209f
Autor:
Bing-Jian Feng, Liang-Dan Sun, Razieh Soltani-Arabshahi, Anne M Bowcock, Rajan P Nair, Philip Stuart, James T Elder, Steven J Schrodi, Ann B Begovich, Gonçalo R Abecasis, Xue-Jun Zhang, Kristina P Callis-Duffin, Gerald G Krueger, David E Goldgar
Publikováno v:
PLoS Genetics, Vol 5, Iss 8, p e1000606 (2009)
Psoriasis is a common inflammatory skin disease characterized by thickened scaly red plaques. Previously we have performed a genome-wide association study (GWAS) on psoriasis with 1,359 cases and 1,400 controls, which were genotyped for 447,249 SNPs.
Externí odkaz:
https://doaj.org/article/95dc36b827f84cbcb5024ea686d7a30f
Autor:
Monica Chang, Charles M Rowland, Veronica E Garcia, Steven J Schrodi, Joseph J Catanese, Annette H M van der Helm-van Mil, Kristin G Ardlie, Christopher I Amos, Lindsey A Criswell, Daniel L Kastner, Peter K Gregersen, Fina A S Kurreeman, Rene E M Toes, Tom W J Huizinga, Michael F Seldin, Ann B Begovich
Publikováno v:
PLoS Genetics, Vol 4, Iss 6, p e1000107 (2008)
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease affecting both joints and extra-articular tissues. Although some genetic risk factors for RA are well-established, most notably HLA-DRB1 and PTPN22, these markers do not fully accoun
Externí odkaz:
https://doaj.org/article/06b63f94b8694508a11164750601eaa3
Autor:
Fina A. S Kurreeman, Leonid Padyukov, Rute B Marques, Steven J Schrodi, Maria Seddighzadeh, Gerrie Stoeken-Rijsbergen, Annette H. M van der Helm-van Mil, Cornelia F Allaart, Willem Verduyn, Jeanine Houwing-Duistermaat, Lars Alfredsson, Ann B Begovich, Lars Klareskog, Tom W. J Huizinga, Rene E. M Toes
Publikováno v:
PLoS Medicine, Vol 4, Iss 12 (2007)
Externí odkaz:
https://doaj.org/article/63d8224143874465a88106bd5390e029
Autor:
Fina A S Kurreeman, Leonid Padyukov, Rute B Marques, Steven J Schrodi, Maria Seddighzadeh, Gerrie Stoeken-Rijsbergen, Annette H M van der Helm-van Mil, Cornelia F Allaart, Willem Verduyn, Jeanine Houwing-Duistermaat, Lars Alfredsson, Ann B Begovich, Lars Klareskog, Tom W J Huizinga, Rene E M Toes
Publikováno v:
PLoS Medicine, Vol 4, Iss 9, p e278 (2007)
BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disorder affecting approximately 1% of the population. The disease results from the interplay between an individual's genetic background and unknown environmental triggers. Although human le
Externí odkaz:
https://doaj.org/article/c24ee77e6681472c9a808f6543ce0fba
Autor:
Wei Li, Robert P. Kimberly, Yu-Lung Lau, Gerald McGwin, Jeffrey C. Edberg, Nan Shen, Quan Zhen Li, Ann B. Begovich, Yun Deng, Xuebing Feng, Jianxin Lu, Monica Chang, Michelle Petri, Kimberly E. Taylor, Betty P. Tsao, Luis M. Vilá, Chack-Yung Yu, Joanne Nititham, Graciela S. Alarcón, Elizabeth E. Brown, Deh Ming Chang, Yonghong Li, Rosalind Ramsey-Goldman, Fei Lan Liu, Lindsey A. Criswell, Lingyun Sun, Joseph J. Catanese, Jian Zhao, John D. Reveille, Rachel Kaiser, Yeong W. Song, Wanling Yang, Edward K. Wakeland
Publikováno v:
Arthritis & Rheumatism. 65:211-215
Objective The increased risk of thrombosis in systemic lupus erythematosus (SLE) may be partially explained by interrelated genetic pathways for thrombosis and SLE. The present study was undertaken to investigate whether 33 established and novel sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357521d6b62f8f3eafc10bd5ad83b5cc
https://doi.org/10.1002/art.37751
https://doi.org/10.1002/art.37751
Autor:
A Hemmings, A T Bansal, Lindsey A. Criswell, Laurent Essioux, A. Kenwright, P Cutler, Ruchi Upmanyu, Soren Germer, Ryma Benayed, Olivier Harari, Ann B. Begovich, Mitchell Martin, Kimberly E. Taylor, J Wang, Adam Platt, Janet S. Lee, Jonathan Marchini
Rheumatoid arthritis (RA) is an immune-mediated inflammatory disease affecting the joints. A heterogeneous response to available therapies demonstrates the need to identify those patients likely to benefit from a particular therapy. Our objective was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8abae4ebe192682e18e6e4930184ed
https://ora.ox.ac.uk/objects/uuid:e69047af-6e04-4bb4-9498-a86405ff7694
https://ora.ox.ac.uk/objects/uuid:e69047af-6e04-4bb4-9498-a86405ff7694
Autor:
Monica Chang, Rosalind Ramsey-Goldman, Rachel Kaiser, Joseph J. Catanese, Michelle Petri, Yonghong Li, Lindsey A. Criswell, Jeffrey C. Edberg, Ann B. Begovich, Elizabeth E. Brown, Robert P. Kimberly, Luis M. Vilá, Graciela S. Alarcón, Kimberly E. Taylor, Gerald McGwin, John D. Reveille
Publikováno v:
The Journal of rheumatology, vol 39, iss 8
Objective.Thrombosis is a serious complication of systemic lupus erythematosus (SLE). We investigated whether genetic variants implicated in thrombosis pathways are associated with thrombosis among 2 ethnically diverse SLE cohorts.Methods.Our discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75fc698c325927b5bb45b774b60974ef
https://doi.org/10.3899/jrheum.111451
https://doi.org/10.3899/jrheum.111451
Autor:
Yue Sun, Elizabeth D. Mellins, Tzielan Lee, Ann B. Begovich, Claudia Macaubas, Jane L. Park, Sheng Yung Chang, Shivani Srivastava, Heather C. Alexander, Chetan Deshpande
Publikováno v:
Clinical Immunology. 136:257-268
We investigated whether circulating monocytes from patients with systemic juvenile idiopathic arthritis (SJIA) are resistant to apoptosis and which apoptotic pathway(s) may mediate this resistance. A microarray analysis of peripheral blood mononuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fadaf43790173ebbe9ee8e18ef38ae1
https://doi.org/10.1016/j.clim.2010.04.003
https://doi.org/10.1016/j.clim.2010.04.003
Autor:
Yonghong Li, Ann B. Begovich
Publikováno v:
Seminars in Immunology. 21:318-327
Talk of numerous genetic risk factors for rheumatoid arthritis (RA) and psoriasis has been percolating for years, but with the exception of the human leukocyte antigen (HLA) region, none have been definitively identified. Recently the results of mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d002ab8f62292de8e2279ae424142d18
https://doi.org/10.1016/j.smim.2009.04.002
https://doi.org/10.1016/j.smim.2009.04.002