Výsledky vyhledávání - "A Awgulewitsch"

Akademický článek

Transcriptome analysis of cardiac endothelial cells after myocardial infarction reveals temporal changes and long-term deficits

Autor: Chitra Basu, Presley L. Cannon, Cassandra P. Awgulewitsch, Cristi L. Galindo, Eric R. Gamazon, Antonis K. Hatzopoulos

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)

Abstract Endothelial cells (ECs) have essential roles in cardiac tissue repair after myocardial infarction (MI). To establish stage-specific and long-term effects of the ischemic injury on cardiac ECs, we analyzed their transcriptome at landmark time

Externí odkaz: https://doaj.org/article/c3e8379179da4c26b3e3f27a328ac2b4

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Akademický článek

902 Loss-of-function variants in SAT1 cause X-linked Childhood-onset Systemic Lupus Erythematosus

Publikováno v: Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)

Externí odkaz: https://doaj.org/article/29d520723cca4e048732eacb99f2b0c0

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Akademický článek

DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse

Autor: Kelsey S. Moore, Reece Moore, Diana B. Fulmer, Lilong Guo, Cortney Gensemer, Rebecca Stairley, Janiece Glover, Tyler C. Beck, Jordan E. Morningstar, Rachel Biggs, Rupak Muhkerjee, Alexander Awgulewitsch, Russell A. Norris

Publikováno v: Journal of Cardiovascular Development and Disease, Vol 9, Iss 2, p 62 (2022)

Mitral valve prolapse (MVP) is a common cardiac valve disease that often progresses to serious secondary complications requiring surgery. MVP manifests as extracellular matrix disorganization and biomechanically incompetent tissues in the adult setti

Externí odkaz: https://doaj.org/article/fe1c8a4e0fff4124a626f256575fe980

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Loss-of-function variants inSAT1cause X-linked childhood-onset systemic lupus erythematosus

Publikováno v: Annals of the Rheumatic Diseases. 81:1712-1721

ObjectivesFamilies that contain multiple siblings affected with childhood onset of systemic lupus erythematosus (SLE) likely have strong genetic predispositions. We performed whole exome sequencing (WES) to identify familial rare risk variants and to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17eac068c58754f15db6357566ed436d
https://doi.org/10.1136/ard-2022-222795

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Akademický článek

Deletion of Cdkn1b in ACI rats leads to increased proliferation and pregnancy-associated changes in the mammary gland due to perturbed systemic endocrine environment.

Autor: Lina Ding, Lauren B Shunkwiler, Nicholas W Harper, Yang Zhao, Kunihiko Hinohara, Sung Jin Huh, Muhammad B Ekram, Jan Guz, Michael J Kern, Alexander Awgulewitsch, James D Shull, Bart M G Smits, Kornelia Polyak

Publikováno v: PLoS Genetics, Vol 15, Iss 3, p e1008002 (2019)

Mammary epithelial progenitors are the normal cell-of-origin of breast cancer. We previously defined a population of p27+ quiescent hormone-responsive progenitor cells in the normal human breast whose frequency associates with breast cancer risk. Her

Externí odkaz: https://doaj.org/article/d67d87ad06f84ad6b3000b0206d5eefa

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