Zobrazeno 1 - 10
of 85
pro vyhledávání: '"A Arockia Jeyaprakash"'
Case report: Identification of a novel variant p.Gly215Arg in the CHN1 gene causing Moebius syndrome
Autor:
Carmen Manso-Bazús, Nino Spataro, Elisabeth Gabau, Viviana P. Beltrán-Salazar, Juan Pablo Trujillo-Quintero, Nuria Capdevila, Anna Brunet-Vega, Neus Baena, A Arockia Jeyaprakash, Victor Martinez-Glez, Anna Ruiz
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background: Moebius Syndrome (MBS) is a rare congenital neurological disorder characterized by paralysis of facial nerves, impairment of ocular abduction and other variable abnormalities. MBS has been attributed to both environmental and genetic fact
Externí odkaz:
https://doaj.org/article/ee8d5c9d7ce1457f9888d02ded0bbba8
Autor:
Desislava P Staneva, Stefan Bresson, Tatsiana Auchynnikava, Christos Spanos, Juri Rappsilber, A Arockia Jeyaprakash, David Tollervey, Keith R Matthews, Robin C Allshire
Publikováno v:
eLife, Vol 11 (2022)
Kinetoplastids are a highly divergent lineage of eukaryotes with unusual mechanisms for regulating gene expression. We previously surveyed 65 putative chromatin factors in the kinetoplastid Trypanosoma brucei. Our analyses revealed that the predicted
Externí odkaz:
https://doaj.org/article/4ac280a143454098a4e658b0fa061093
Autor:
Marco Novais-Cruz, Maria Alba Abad, Wilfred FJ van IJcken, Niels Galjart, A Arockia Jeyaprakash, Helder Maiato, Cristina Ferrás
Publikováno v:
eLife, Vol 7 (2018)
Recent studies have challenged the prevailing dogma that transcription is repressed during mitosis. Transcription was also proposed to sustain a robust spindle assembly checkpoint (SAC) response. Here, we used live-cell imaging of human cells, RNA-se
Externí odkaz:
https://doaj.org/article/c3856abb5ad74415bb65bc3b4e3502e2
Autor:
Oscar Molina, Giulia Vargiu, Maria Alba Abad, Alisa Zhiteneva, A. Arockia Jeyaprakash, Hiroshi Masumoto, Natalay Kouprina, Vladimir Larionov, William C. Earnshaw
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Centromeres are centrochromatin domains with CENP-A and H3 nucleosomes carrying transcription-associated modifications. Here the authors target synthetic modules to the centromeres to show that transcription plus histone modifications are required fo
Externí odkaz:
https://doaj.org/article/7355b73cb5fc45f4a8cb124130f7a9aa
Autor:
Virginie Roure, Bethan Medina-Pritchard, Vasiliki Lazou, Luciano Rago, Eduard Anselm, Daniela Venegas, A. Arockia Jeyaprakash, Patrick Heun
Publikováno v:
Cell Reports, Vol 29, Iss 2, Pp 464-479.e5 (2019)
Summary: The centromere is an essential chromosomal region required for accurate chromosome segregation. Most eukaryotic centromeres are defined epigenetically by the histone H3 variant, centromere protein (CENP)-A, yet how its self-propagation is ac
Externí odkaz:
https://doaj.org/article/ebbc10f9431342a7a99291e7ca91baec
Autor:
Koly Aktar, Thomas Davies, Ioanna Leontiou, Ivan Clark, Christos Spanos, Edward Wallace, Laura Tuck, A. Arockia Jeyaprakash, Kevin G. Hardwick
Cryptococcus neoformansis an opportunistic, human fungal pathogen which undergoes fascinating switches in cell cycle control and ploidy when it encounters stressful environments such as the human lung. Here we carry out a mechanistic analysis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6c720665a14ca92d6084ffe90f6a02d
https://doi.org/10.1101/2023.04.09.536157
https://doi.org/10.1101/2023.04.09.536157
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Protein kinases are major regulators of mitosis, with over 30% of the mitotic proteome phosphorylated on serines, threonines and tyrosines. The human genome encodes for 518 kinases that have a structurally conserved catalytic domain and includes abou
Externí odkaz:
https://doaj.org/article/9d2336d823114ff0aed99f419f88cbb6
Autor:
Desislava P Staneva, Stefan Bresson, Tatsiana Auchynnikava, Christos Spanos, Juri Rappsilber, A Arockia Jeyaprakash, David Tollervey, Keith R Matthews, Robin C Allshire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::210b39689db284d59e7e87321862d0f3
https://doi.org/10.7554/elife.83135.sa2
https://doi.org/10.7554/elife.83135.sa2
Autor:
Ioanna Leontiou, Thomas Davies, Ivan Clark, Koly Aktar, Ardra Pamburayath Suresh, Maria Alba Abad, Christos Spanos, Kyung-Tae Lee, Yong-Sun Bahn, A. Arockia Jeyaprakash, Kevin G. Hardwick
Cryptococcus neoformans (Cn) is an important human pathogen and a model system for basidiomycetes. Here we carry out a dissection of its spindle assembly checkpoint (SAC), focusing on Bub1 and Bub3. In many eukaryotes, including humans, Saccharomyces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b5d7b683df72544d740674c5894ab51
https://doi.org/10.1101/2022.09.21.508923
https://doi.org/10.1101/2022.09.21.508923
Autor:
Desislava P. Staneva, Stefan Bresson, Tatsiana Auchynnikava, Christos Spanos, Juri Rappsilber, A. Arockia Jeyaprakash, David Tollervey, Keith R Matthews, Robin C. Allshire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62ce64633d6b1f61a75e9bff71b8647a
https://doi.org/10.15252/rc.2022596580
https://doi.org/10.15252/rc.2022596580